Patents by Inventor Makoto Hirayama
Makoto Hirayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11952344Abstract: Provided is a heterocyclic compound that can have an antagonistic action on an NMD A receptor containing the NR2B subunit and that is expected to be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like. A compound represented by the formula (I), wherein each symbol is as defined in the DESCRIPTION, or a salt thereof.Type: GrantFiled: September 25, 2020Date of Patent: April 9, 2024Assignee: Takeda Pharmaceutical Company LimitedInventors: Yuya Oguro, Makoto Kamata, Shuhei Ikeda, Takeshi Wakabayashi, Norihito Tokunaga, Taku Kamei, Mitsuhiro Ito, Shigemitsu Matsumoto, Hirotaka Kamitani, Takaharu Hirayama, Toshio Tanaka, Hiroshi Banno, Nobuyuki Takakura, Jinichi Yonemori, Takuya Fujimoto
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Publication number: 20200116714Abstract: To provide a device capable of cancer diagnosis with high sensitivity and specificity, a cancer diagnosis device (1) includes: an extracellular vesicle capturing section (16 to 18) including immobilization supports on which lectins are immobilized respectively, the lectins being each capable of binding specifically to a surface sugar chain included in an extracellular vesicle derived from a cancer cell, the immobilization supports corresponding respectively to one or more kinds of the surface sugar chain; and a detecting section configured to detect a microRNA included in the extracellular vesicle.Type: ApplicationFiled: November 11, 2019Publication date: April 16, 2020Inventors: Kanji HORI, Makoto HIRAYAMA, Ikuro MARUYAMA, Yoshihiro TAGUCHI, Hiroshi KUROKAWA, Kenya KOBAYASHI, Hiroyoshi MINAKUCHI
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Publication number: 20140087395Abstract: The object was to provide a method for distinguishing between species within the genus Staphylococcus; binding affinities between many types of lectins and bacteria belonging to the genus Staphylococcus were examined; and lectins of Tachylectin-2, LEL, KAA1, BCL11, CBA, HAA, HPA, STL, proBCA1, proBCA2, ULL, DSA, PWM, UDA, WFL, hypninA3, BCL11d, CFA1, CFA2, CLA, MPA1, MPA2, AC-avranin, algCSA, BML11b, BML11c, etc. were selected. Further, it was found that these lectins could be used to distinguish between species within the genus Staphylococcus.Type: ApplicationFiled: March 22, 2012Publication date: March 27, 2014Applicants: HIROSHIMA UNIVERSITY, GLYENCE CO., LTD.Inventors: Hideaki Takeuchi, Koji Imamura, Uichiro Yabe, Kanji Hori, Makoto Hirayama
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Publication number: 20110187321Abstract: A control signal is superimposed on an AC power at the time of charging the battery of an electric car in a non-contact manner by electric power outputted from a feeding apparatus. A feeding apparatus 11 includes a carrier oscillator 21 for outputting an AC power, an ASK modulator 22 for superimposing a control signal on the AC power outputted from the carrier oscillator 21 according to the ASK modulation method, a power amplifier 23 for amplifying the AC power modulated by the ASK modulator 22, and a first resonance coil 24 for outputting the AC power amplified by the power amplifier 23. A charging apparatus 12 to be provided on an electric car includes a second resonance coil 31 for receiving the AC power transmitted from the first resonance coil 24, an ASK demodulator 34 for demodulating the received AC power to thereby extract the control signal, and a rectifier 33 which rectifiers the received AC power to obtain a DC power and supplies the DC power to a battery 35.Type: ApplicationFiled: September 11, 2009Publication date: August 4, 2011Applicant: YAZAKI CORPORATIONInventor: Makoto Hirayama
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Patent number: 7154883Abstract: In executing a setup procedure of a call from a VoIP gateway on the originating side to a media gateway on the destination side via a gate keeper, an authentication key is transmitted from the gate keeper to the VoIP gateway and the media gateway. The VoIP gateway on the originating side transmits to the media gateway on the destination side an admissions confirm (ACF) after attaching the authentication key. Then, the media gateway collates the authentication key obtained from the originator VoIP gateway with the authentication key obtained from the gate keeper and continues the call setup procedure only when the two authentication keys coincide with each other. On the other hand, in case of non-coincidence, the gate keeper carries out a call release. Through this, an illegal connection call not routing through the gate keeper is excluded without fail.Type: GrantFiled: May 3, 2002Date of Patent: December 26, 2006Assignee: Hitachi, Ltd.Inventors: Makoto Hirayama, Kazuhiro Kita, Tomohide Sugimoto
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Publication number: 20050272271Abstract: A method for processing a target substrate (10) in a semiconductor processing apparatus (1) controls temperature of a first substrate (10) at a process temperature inside a process container (2), while supplying a process gas into the process container, thereby subjecting the first substrate to a semiconductor process, during which a by-product film is formed inside the process container. After the semiconductor process and unload of the first substrate (10) out of the process container (2), a reforming gas is supplied into the process container, thereby subjecting the by-product film to a reformation process, which is set to reduce thermal reflectivity of the by-product film. After the reformation process, temperature of a second substrate (10) is controlled at the process temperature inside the process container (2), while supplying the process gas into the process container, thereby subjecting the second substrate to the semiconductor process.Type: ApplicationFiled: February 4, 2004Publication date: December 8, 2005Applicant: TOKYO ELECTRON LIMITEDInventors: Haruhiko Furuya, Yuihiro Morozumi, Hiroaki Ikegawa, Makoto Hirayama, Yuichi Ito
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Publication number: 20030123434Abstract: In executing a setup procedure of a call from a VoIP gateway on the originating side to a media gateway on the destination side via a gate keeper, an authentication key is transmitted from the gate keeper to the VoIP gateway and the media gateway. The VoIP gateway on the originating side transmits to the media gateway on the destination side an admissions confirm (ACF) after attaching the authentication key. Then, the media gateway collates the authentication key obtained from the originator VoIP gateway with the authentication key obtained from the gate keeper and continues the call setup procedure only when the two authentication keys coincide with each other. On the other hand, in case of non-coincidence, the gate keeper carries out a call release. Through this, an illegal connection call not routing through the gate keeper is excluded without fail.Type: ApplicationFiled: May 3, 2002Publication date: July 3, 2003Inventors: Makoto Hirayama, Kazuhiro Kita, Tomohide Sugimoto
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Patent number: 6249764Abstract: In the method, speech files each representing speech information are provided. At least one of the speech files is a hyperspeech file that represents speech information and includes a hot spot specification specifying a hot spot in the speech information. The hot spot identifies additional speech information. The hot spot specification comprises a hot spot definition defining the hot spot and an identifier identifying another of the speech files that represents the additional speech information. A speech information presentation operation is iteratively performed until the desired speech information is presented. In this operation, a speech file retrieval operation that retrieves one of the speech files is performed, any hot spot specification in the speech file is extracted, a speech signal is generated from the speech file, and the speech information is presented in response to the speech signal.Type: GrantFiled: February 25, 1999Date of Patent: June 19, 2001Assignee: Hewlett-Packard CompanyInventors: Takahiko Kamae, Makoto Hirayama
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Patent number: 5327624Abstract: A method for forming a thin film on a semiconductor substrate wherein the substrate is transferred between an auxiliary chamber having an inert atmosphere to a reaction chamber having a reactive atmosphere, and wherein the inert and the reactive atmospheres exist concurrently during transfer.Type: GrantFiled: December 18, 1990Date of Patent: July 12, 1994Assignee: Mitsubishi Denki Kabushiki KaishaInventor: Makoto Hirayama
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Patent number: 5023750Abstract: A capacitor includes a lower electrode formed from a layer of silicon or polycrystalline silicon, a single or multi-layer dielectric film such as a nitride film, and an upper electrode formed on the dielectric film. The dielectric film is formed, after a surface layer of the lower electrode has been removed by etching, on a new surface of the lower electrode continuously in a non-oxidizing atmosphere. By this process, formation of an incidental oxide film between the dielectric film and the lower electrode can be prevented.In a direct contact region of the conductive layer, the surface of the contact region is also etched by dry chemical etching, and thereafter the conductive layer is formed in an oxygen-free atmosphere. By doing so, generation of an incidental oxide film having high resistance can be prevented, whereby the contact characteristic can be improved.Type: GrantFiled: February 21, 1990Date of Patent: June 11, 1991Assignee: Mitsubishi Denki Kabushiki KaishaInventor: Makoto Hirayama
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Patent number: 4905068Abstract: A cell plate (6) is formed on a main surface of a semiconductor substrate (7) with an insulating film (8) interposed therebetween and an interconnection (1) having T-shape cross section is formed on the cell plate (6) with an interlayer insulating film (11) interposed therebetween. An upper insulating film (12) is formed to cover the interconnection (1).Type: GrantFiled: January 13, 1988Date of Patent: February 27, 1990Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Shinichi Satoh, Makoto Hirayama, Masao Nagatomo, Ikuo Ogoh, Yoshikazu Ohno, Masato Fujinaga
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Patent number: 4845228Abstract: The present invention relates to cyclohexanone derivatives represented by general formula: ##STR1## wherein R represents a hydrogen atom or an acetyl group. The cyclohexanone derivatives are important intermediates for producing isoquinoline derivatives which are useful as drugs, especially for heart drugs.Type: GrantFiled: January 26, 1988Date of Patent: July 4, 1989Assignee: Mitsui Toatsu Chemicals, Inc.Inventors: Tsuneji Suzuki, Sannohe, Kunio, Toshihiko Ito, Masahiko Maruyama, Joji Kamiya, Makoto Hirayama, Takafumi Kitano, Akira Awaya
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Patent number: 4824952Abstract: An isoquinoline derivative of the following formula: ##STR1## wherein R.sub.1 is a methyl or a methoxymethyl group and R.sub.2 and R.sub.3 are each a hydrogen atom or a methyl, ethyl, methoxy, a cyclohexyl, a phenyl, a 3,4-dimethoxyphenyl, a pyridyl or an oxo (.dbd.O) group;and therapeutically acceptable salts thereof which exhibit a low toxicity and a wide range of safety and are highly useful as a cardiotonic medication.Type: GrantFiled: July 12, 1985Date of Patent: April 25, 1989Assignee: Mitsui Toatsu Chemicals, Inc.Inventors: Tsuneji Suzuki, Kunio Sannohe, Toshihiko Ito, Masahiko Maruyama, Joji Kamiya, Makoto Hirayama, Takafumi Kitano, Akira Awaya
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Patent number: 4822756Abstract: The present invention comprises a reaction furnace including a fixed capsule having an air atmosphere to be replaced with a predetermined atmosphere, with a semiconductor member to be treated placed therein. A movable capsule initially receives the member and has an atmosphere replaced with a predetermined one before the member to be treated is transferred to the fixed capsule. The movable capsule receives the member at a receiving location and is moved to a delivery location where it is connected to a loading chamber. A method of operating the reaction furnace is also disclosed.Type: GrantFiled: November 18, 1987Date of Patent: April 18, 1989Assignee: Mitsubishi Denki Kabushiki KaishaInventor: Makoto Hirayama
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Patent number: 4802842Abstract: In a heating furnace for forming films on semiconductor substrates (1), holding means (2, 4) for holding semiconductor substrates (1) are provided with projections (3, 5) for holding at least part of bottom faces of the semiconductor substrates (1) horizontally with predetermined spacing between the projections.Type: GrantFiled: August 4, 1987Date of Patent: February 7, 1989Assignee: Mitsubishi Denki Kabushiki KaishaInventor: Makoto Hirayama
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Patent number: 4782154Abstract: The isoquinoline derivatives represented by the following general formula (I) are useful as cardiotonics having high cardiotonic activity and low toxicity: ##STR1## where R.sub.1 represents a lower C.sub.1 -C.sub.4 alkyl group or cyclopropyl group,R.sub.2 represents formyl group, lower C.sub.1 -C.sub.4 alkanoyl group and benzoyl group, lower C.sub.1 -C.sub.4 alkyl group, lower C.sub.1 -C.sub.4 alkenyl group, lower C.sub.1 -C.sub.4 hydroxy substituted alkyl group, C.sub.1 -C.sub.4 perfluoroalkyl group andR.sub.3 represents 4-pyridyl group or 2-pyridyl group respectively,and the therapeutically acceptable salts thereof are also useful as cardiotonics.Type: GrantFiled: July 17, 1987Date of Patent: November 1, 1988Assignee: Mitsui Toatsu Chemicals, Inc.Inventors: Tatsuo Kaiho, Seitaro Kajiya, Kengo Otsuka, Masahiko Maruyama, Makoto Hirayama
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Patent number: 4639521Abstract: Isoquinoline derivatives represented by the general formula (I): ##STR1## wherein R.sub.1 denotes a hydrogen or halogen atom, or a nitro or acetyl group, and R.sub.2 denotes a hydrogen atom, or a methyl, methoxy, phenyl, 4-pyridyl or 2-pyridyl group, and therapeutically acceptable salts thereof have high cardiotonic activity and low toxicity.Type: GrantFiled: June 20, 1986Date of Patent: January 27, 1987Assignee: Mitsui Toatsu Chemicals, Inc.Inventors: Kunio Sannohe, Kengo Otsuka, Toshohiko Ito, Masahiko Maruyama, Takafumi Kitano, Makoto Hirayama