Patents by Inventor Makoto Kitoh

Makoto Kitoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7220773
    Abstract: A novel pyrrole derivative represented by the following formula (1) and a salt thereof: wherein R1 means substituted alkenyl, etc.; R2 means substituted benzoyl, etc.; and R3 to R5 each means hydrogen, alkyl, halogeno, etc. The derivative and salt have antidiabetic activity.
    Type: Grant
    Filed: April 17, 2002
    Date of Patent: May 22, 2007
    Assignee: Dainippon Sumitomo Pharma Co., Ltd.
    Inventors: Ryu Nagata, Katsunori Maruta, Kiyotaka Iwai, Makoto Kitoh, Kantaro Ushiroda, Kozo Yoshida
  • Publication number: 20050227978
    Abstract: Medicament being useful as a fibrosis inhibitor for organs or tissues, which comprises a compound of the formula (I): wherein Ring Z is optionally substituted pyrrole ring, etc.; W2 is —CO—, —SO2—, optionally substituted C1-C4 alkylene, etc.; Ar2 is optionally substituted aryl, etc.; W1 and Ar1 mean the following (1) and (2): (1) W1 is optionally substituted C1-C4 alkylene, etc.; Ar1 is optionally substituted bicyclic heteroaryl having 1 to 4 nitrogen atoms as ring-forming atoms: (2) W1 is optionally substituted C2-C5 alkylene, optionally substituted C2-C5 alkenylene, etc.; and Ar1 is aryl or monocyclic heteroaryl, which is substituted by carboxyl, alkoxycarbonyl, etc. at the ortho- or meta-position thereof with respect to the binding position of W1, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: January 28, 2003
    Publication date: October 13, 2005
    Applicant: Sumitomo Pharmaceuticals Co., Ltd.
    Inventors: Teruhisa Tokunaga, Willian Hume, Makoto Kitoh, Ryu Nagata, Michiko Kishino, Tsutomu Nakagawa, Jun Nagamine, Mutsuo Taiji
  • Publication number: 20040209939
    Abstract: Pyrrole derivatives represented by the following formula: 1
    Type: Application
    Filed: May 7, 2004
    Publication date: October 21, 2004
    Applicant: Sumitomo Pharmaceuticals Co., Ltd.
    Inventors: Teruhisa Tokunaga, William Ewan Hume, Makoto Kitoh, Ryu Nagata
  • Publication number: 20040162331
    Abstract: A novel pyrrole derivative represented by the following formula (1) and a salt thereof: 1
    Type: Application
    Filed: October 16, 2003
    Publication date: August 19, 2004
    Inventors: Ryu Nagata, Katsunori Maruta, Kiyotaka Iwai, Makoto Kitoh, Kantaro Ushiroda, Kozo Yoshida
  • Patent number: 6759429
    Abstract: Pyrrole derivatives represented by the following formula: wherein Ring Z is an optionally substituted pyrrole ring, etc.; W2 is —CO—, —SO2—, an optionally substituted C1-C4 alkylene, etc.; Ar2 is an optionally substituted aryl, etc.; W1 and Ar1 mean the following (1) and (2): (1) W1 is an optionally substituted C1-C4 alkylene, etc.; Ar1 is an optionally substituted bicyclic heteroaryl having 1 to 4 nitrogen atoms as ring-forming atoms: (2) W1 is an optionally substituted C2-C5 alkylene, an optionally substituted C2-C5 alkenylene, etc.; and Ar1 is an aryl or monocyclic heteroaryl, which are substituted by carboxyl, an alkoxycarbonyl, etc. at the ortho- or meta-position thereof with respect to the binding position of W1, or a pharmaceutically acceptable salt thereof. These compounds are useful as medicaments such as a fibrosis inhibitor for organs or tissues.
    Type: Grant
    Filed: January 28, 2003
    Date of Patent: July 6, 2004
    Assignee: Sumitomo Pharmaceuticals Co., Ltd.
    Inventors: Teruhisa Tokunaga, William Ewan Hume, Makoto Kitoh, Ryu Nagata
  • Publication number: 20030181496
    Abstract: Pyrrole derivatives represented by the following formula: 1
    Type: Application
    Filed: January 28, 2003
    Publication date: September 25, 2003
    Inventors: Teruhisa Tokunaga, William Ewan Hume, Makoto Kitoh, Ryu Nagata
  • Patent number: 5651867
    Abstract: A plasma processing apparatus comprising: a vacuum container; an evacuation means for keeping the interior of the vacuum container at a pressure not higher than atmospheric pressure; a substrate support device for supporting a substrate to be subjected to plasma processing; an electrode for generating plasma in cooperation with the substrate support; a voltage supply for applying a voltage to the electrode; a gas introducing system for introducing a gaseous material into a space where the plasma is produced; a surrounding member for enclosing the space above the substrate support, and a drive for relatively moving the surrounding member to space an end of the surrounding member proximate from the substrate from at least one of the substrate support and the substrate supported thereon by a distance which is short enough to suppress plasma leakage during the plasma processing and to position the end of the surrounding member away from said at least one of the substrate support and the substrate thereon for char
    Type: Grant
    Filed: October 2, 1990
    Date of Patent: July 29, 1997
    Assignee: Hitachi, Ltd.
    Inventors: Yuichi Kokaku, Hiroyuki Kataoka, Makoto Kitoh, Shigehiko Fujimaki, Satoshi Matsunuma, Kenji Furusawa, Nobuo Nakagawa, Katsuo Abe, Masaaki Hayashi
  • Patent number: 5409738
    Abstract: Disclosed are a recording medium comprising a substrate, a thin film for recording formed on at least one side of the substrate, a protective layer formed on the thin film, and a lubricative film formed on the protective layer, the lubricative film comprising an oxidative polymerization product having main molecular chains chemically bonded to the protective film; and a process for producing the recording medium. This recording medium is excellent in lubricity and durability, and the layers formed thereon can be very thin.
    Type: Grant
    Filed: March 23, 1994
    Date of Patent: April 25, 1995
    Assignee: Hitachi, Ltd.
    Inventors: Satoshi Matsunuma, Yuichi Kokaku, Makoto Kitoh, Shigehiko Fujimaki
  • Patent number: 5300189
    Abstract: A surface treatment method and apparatus permitting the treatment of a film with plasma with a high treatment speed and a high efficiency without uselessly complicating the construction of a device for realizing it are disclosed. The area where the counter electrode is in contact with the plasma is sufficiently larger than the area where the rotating electrode is in contact therewith. The ratio of the areas is preferably not smaller than 1.5 and the etching speed may be increased to a value more than ten times as great as that obtained by a prior art method.
    Type: Grant
    Filed: May 20, 1987
    Date of Patent: April 5, 1994
    Assignee: Hitachi, Ltd.
    Inventors: Yuichi Kokaku, Makoto Kitoh, Yoshinori Honda
  • Patent number: 5275850
    Abstract: A magnetic disk comprising a nonmagnetic substrate, a metallic thin film magnetic layer provided on the substrate and a hard carbon protective layer provided on the magnetic layer, the hard carbon protective layer containing at least one metal element of silicon, germanium, tin and lead, or further containing fluorine, formed by bias plasma CVD treatment, has a high attrition resistance, a high peeling resistance and a high crack resistance or further a higher corrosion resistance.
    Type: Grant
    Filed: September 4, 1991
    Date of Patent: January 4, 1994
    Assignee: Hitachi, Ltd.
    Inventors: Makoto Kitoh, Yuichi Kokaku, Makiko Itoh
  • Patent number: 5104709
    Abstract: The magnetic recording medium of the present invention comprises(a) a non-magnetic substrate,(b) a magnetic recording layer containing at least one ferromagnetic substance on at least one side of the substrate,(c) a protective layer the magnetic recording layer, and(d) a lubricant layer on the protective layer, wherein an adhesion-strengthening substance which is at least one member selected from the group consisting of metals and metal compounds is distributed substantially uniformly on the layer (c) at the interface between the layer (c) and the layer (d) so as not to cover the whole surface of the layer (c) and so as to contact also with the layer (d).
    Type: Grant
    Filed: June 19, 1990
    Date of Patent: April 14, 1992
    Assignee: Hitachi, Ltd.
    Inventors: Yuichi Kokaku, Satoshi Matsunuma, Shigehiko Fujimaki, Makoto Kitoh, Kenji Furusawa
  • Patent number: 5073243
    Abstract: An optical recording medium is made by sputtering a polymeric material in an evacuated chamber to form an under layer on a substrate having a preformed grooved pattern of prepits and pregrooves, and then forming a recording layer on the underlayer in the chamber continuously after forming the underlayer. Said under layer is made of a high polymeric material which can be melted, sublimated, or decomposed at a lower temperature than the melting point, the sublimating point, or the decomposing temperature of said recording layer. Accordingly, said under layer can relax the thermal shock transferred from said substrate into said recording layer, and the deformation of said substrate can be prevented, even though a laser beam for playback is repeatedly radiated onto said recording layer, and said optical recording medium has a larger recording sensitivity than the recording sensitivity of an optical recording disc of a prior art.
    Type: Grant
    Filed: December 29, 1989
    Date of Patent: December 17, 1991
    Assignees: Hitachi Maxwell, Ltd, Hitachi, Ltd
    Inventors: Akira Gotoh, Yukinobu Yamazaki, Naoyuki Kikuchi, Shinkichi Horigome, Motoyasu Terao, Horoyuki Suzuki, Makoto Kitoh, Yuichi Kokaku, Mitsuru Shimizu
  • Patent number: 4908250
    Abstract: In an optical recording medium, an under layer is formed between an even pattern of a substrate and a recording layer, and said under layer is made of a high polymeric material which can be melted, sublimated, or decomposed at a lower temperature than the melting point, the sublimating point, or the decomposing temperature of said recording layer. Accordingly, said under layer can relax the thermal shock transferred from said substrate into said recording layer, and the deformation of said substrate can be prevented, even through a laser beam for playback is repeatedly radiated onto said recording layer, and said optical recording medium has a larger recording sensitivity than the recording sensitivity of an optical recording disc of a prior art.
    Type: Grant
    Filed: September 19, 1988
    Date of Patent: March 13, 1990
    Assignees: Hitachi Maxell, Ltd., Hitachi, Ltd.
    Inventors: Akira Gotoh, Yukinobu Yamazaki, Naoyuki Kikuchi, Shinkichi Horigome, Motoyasu Terao, Hiroyuki Suzuki, Makoto Kitoh, Yuichi Kokaku, Mitsuru Shimizu
  • Patent number: 4713288
    Abstract: Disclosed is a magnetic recording medium in which a magnetic layer of a ferromagnetic material, a layer of an organic material and a layer of carbon are formed on a substrate in this order.The magnetic recording medium has the benefit of remarkably extended life time because peeling and removing of the carbon protective layer can be prevented so that carbon can exerts its own lubricating action during the sliding contact of the magnetic recording medium with a magnetic head.
    Type: Grant
    Filed: June 4, 1986
    Date of Patent: December 15, 1987
    Assignee: Hitachi, Ltd.
    Inventors: Yuuichi Kokaku, Makoto Kitoh, Yoshinori Honda
  • Patent number: 4460535
    Abstract: Good adhesion to cases or bobbins of flyback transformers is realized in the flyback transformers produced by insulation treatment with an unsaturated polyester resin adhesive.
    Type: Grant
    Filed: December 4, 1981
    Date of Patent: July 17, 1984
    Assignees: Hitachi, Ltd., Hitachi Chemical Company, Ltd.
    Inventors: Makoto Kitoh, Tetsuo Tajima, Noboru Terunuma, Noboru Mitsugi, Akira Kageyama