Patents by Inventor Makoto Mitarai

Makoto Mitarai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10166313
    Abstract: A bone-repairing agent excellent in workability and applicability to clinical surgical techniques and having a drastically enhanced bone formation rate, obtained by including an elastin hydrolysate in a complex of DNA and at least one selected from the group consisting of protamine, a protamine derivative, and a protamine hydrolysate can be provided. A medical or dental material for bone formation using this bone-repairing agent can be provided.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: January 1, 2019
    Assignee: MARUHA NICHIRO CORPORATION
    Inventors: Tadao Fukushima, Jun Yamazaki, Jun Ohno, Masako Toda, Makoto Mitarai, Keishi Iohara
  • Publication number: 20170354177
    Abstract: A composition with an enhanced antifungal activity, which comprises peptides as a protamine hydrolysate and which is suitable for industrial application at a low cost, can be provided, by using a combination of a protamine hydrolysate and a terpene alcohol as an active ingredient of a composition having an antifungal activity.
    Type: Application
    Filed: September 1, 2015
    Publication date: December 14, 2017
    Applicants: MARUHA NICHIRO CORPORATION, TEIKYO UNIVERSITY
    Inventors: Keishi IOHARA, Makoto MITARAI, Shigeru ABE, Kazumi HAYAMA
  • Patent number: 9486496
    Abstract: A medical or dental material can be prepared by using, as an active ingredient, at least one of a protamine, and derivatives thereof and hydrolysates thereof, or a complex of at least one of a protamine, and derivatives thereof and hydrolysates thereof with an anionic high molecular weight compound. As a result, an antibacterial agent against periodontal disease-causing bacteria can be provided, which is highly safe without concern of a side effect. A medical or dental material can be also provided, which exhibits antimicrobial activity on periodontal disease-causing bacteria and additionally has insolubility in water and good formability.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: November 8, 2016
    Assignees: MARUHA NICHIRO CORPORATION
    Inventors: Tadao Fukushima, Tohru Hayakawa, Yoshio Okahata, Makoto Mitarai, Keishi Iohara, Hiroyuki Enari, Haruchika Sekido
  • Publication number: 20160235888
    Abstract: A bone-repairing agent excellent in workability and applicability to clinical surgical techniques and having a drastically enhanced bone formation rate, obtained by including an elastin hydrolysate in a complex of DNA and at least one selected from the group consisting of protamine, a protamine derivative, and a protamine hydrolysate can be provided. A medical or dental material for bone formation using this bone-repairing agent can be provided.
    Type: Application
    Filed: September 25, 2013
    Publication date: August 18, 2016
    Applicant: MARUHA NICHIRO CORPORATION
    Inventors: Tadao FUKUSHIMA, Jun YAMAZAKI, Jun OHNO, Masako TODA, Makoto MITARAI, Keishi IOHARA
  • Publication number: 20110257094
    Abstract: A medical or dental material can be prepared by using, as an active ingredient, at least one of a protamine, and derivatives thereof and hydrolysates thereof, or a complex of at least one of a protamine, and derivatives thereof and hydrolysates thereof with an anionic high molecular weight compound. As a result, an antibacterial agent against periodontal disease-causing bacteria can be provided, which is highly safe without concern of a side effect. A medical or dental material can be also provided, which exhibits antimicrobial activity on periodontal disease-causing bacteria and additionally has insolubility in water and good formability.
    Type: Application
    Filed: December 21, 2009
    Publication date: October 20, 2011
    Applicants: MARUHA NICHIRO FOODS, INC.
    Inventors: Tadao Fukushima, Tohru Hayakawa, Yoshio Okahata, Makoto Mitarai, Keishi Iohara, Hiroyuki Enari, Haruchika Sekido