Patents by Inventor Makoto Ohyama

Makoto Ohyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline anti-trichophyton agents and preparation process thereof
    Patent number: 10562858
    Abstract: A crystal form of 2-(3,5-dimethyl-1H-pyrazol-1-yl)-5-methylphenol which is stable and has high purity for preservation, industrial manufacturing, and circulation, and process for providing the same by using a boron compound.
    Type: Grant
    Filed: August 12, 2015
    Date of Patent: February 18, 2020
    Assignee: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Toshiro Sasaki, Takahiro Imai, Kenichiro Mori, Makoto Ohyama, Takashi Watanabe
  • CRYSTALLINE ANTI-TRICHOPHYTON AGENTS AND PREPARATION PROCESS THEREOF
    Publication number: 20170233346
    Abstract: A crystal form of 2-(3,5-dimethyl-1H-pyrazol-1-yl)-5-methylphenol which is stable and has high purity for preservation, industrial manufacturing, and circulation, and process for providing the same by using a boron compound.
    Type: Application
    Filed: August 12, 2015
    Publication date: August 17, 2017
    Applicant: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Toshiro SASAKI, Takahiro IMAI, Kenichiro MORI, Makoto OHYAMA, Takashi WATANABE
  • Topical antifungal agent
    Patent number: 8889727
    Abstract: An anti-fungal agent for tinea comprising as active ingredient a compound having the skeleton of 2-(1H-pyrazol-1-yl)phenol represented by the following formula (I) or (II) or a salt thereof is provided
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: November 18, 2014
    Assignee: Meiji Seika Pharma Co., Ltd.
    Inventors: Makoto Ohyama, Yuji Tabata, Maiko Iida, Kaori Kaneda, Sho Takahata
  • TOPICAL ANTIFUNGAL AGENT
    Publication number: 20130317074
    Abstract: An anti-fungal agent for tinea comprising as active ingredient a compound having the skeleton of 2-(1H-pyrazol-1-yl)phenol represented by the following formula (I) or (II) or a salt thereof is provided
    Type: Application
    Filed: January 30, 2012
    Publication date: November 28, 2013
    Inventors: Makoto Ohyama, Yuji Tabata, Maiko Iida, Kaori Kaneda, Sho Takahata
  • Derivatives of cyclodepsipeptide PF1022 substance
    Patent number: 6329338
    Abstract: Novel derivatives of PF1022 substance, which are cyclodepsipeptides represented by the general formula (I) shown below or their salts are useful as anthelmintic agent for prevention or treatment of parasitic infections.
    Type: Grant
    Filed: May 20, 1998
    Date of Patent: December 11, 2001
    Assignees: Meiji Seika Kaisha, Ltd., Bayer Aktiengesellschaft
    Inventors: Osamu Sakanaka, Yumiko Okada, Makoto Ohyama, Maki Matsumoto, Masaaki Takahashi, Yasushi Murai, Katsuharu Iinuma, Achim Harder, Norbert Mencke, Gerhard Bonse, Peter Jeschke
  • Cyclic depsipeptide PF 1022G
    Patent number: 6146853
    Abstract: Known cyclic depsipeptides which are PF 1022F substance and PF 1022H substance, as well as a novel cyclic depsipeptide, PF 1022G substance, are now prepared simultaneously by cultivating a fungal strain capable of producing PF 1022F substance, PF 1022G substance and PF 1022H substance represented by the known PF 1022 strain (deposited under FERM BP-2671) which is a kind of fungus belonging to asporous imperfect fungi (the order Agonomycetales) and is presumable to belong to the genus Xylaria or the genus Rosellinia in the family Xylariaceae.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: November 14, 2000
    Assignee: Meiji Seika Kaisha Ltd.
    Inventors: Makoto Ohyama, Masaaki Takahashi, Yoshiya Shigematsu, Osamu Sakanaka, Yashushi Murai, Katsuharau Iinuma
  • Preparation of cyclic depsipeptide compounds and a novel cyclic depsipeptide
    Patent number: 6043058
    Abstract: Known cyclic depsipeptides which are PE 1022F substance and PF 1022H substance, as well as a novel cyclic depsipeptide, PF 1022G substance, are now prepared simultaneously by cultivating a fungal strain capable of producing PF 1022F substance, PF 1022G substance and PF 1022H substance represented by the known PE 1022 strain (deposited under FERM BP-2671) which is a kind of fungus belonging to asporous imperfect fungi (the order Agonomycetales) and is presumable to belong to the genus Xylaria or the genus Rosellinia in the family Xylariaceae.
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: March 28, 2000
    Assignee: Maiji Seika Kaisha Ltd.
    Inventors: Makoto Ohyama, Masaaki Takahashi, Yoshiya Shigematsu, Osamu Sakanaka, Yashushi Murai, Katsuharau Iinuma
  • Derivatives of cyclodepsipeptide PF 1022
    Patent number: 5747448
    Abstract: Novel PF 1022 derivatives--cyclodepsipeptides represented by the below-described formula (I)--and acid addition salts thereof, which have been synthesized according to the present invention, have anthelmintic activities against various parasitic worms which are parasitic on human bodies, domestic animals and pet animals. They are therefore useful as anthelmintics for the prevention or treatment of parasitic infections. ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, Q, X, Y and Z have been defined herein.
    Type: Grant
    Filed: September 8, 1995
    Date of Patent: May 5, 1998
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Makoto Ohyama, Maki Ohishi, Yumiko Okada, Masao Koyama, Shinjiro Sumi, Yasushi Murai, Masayuki Takagi, Tadaaki Okada, Osamu Sakanaka, Toshio Yoneta, Katsuharu Iinuma, Seiji Shibahara