Abstract: An object of the present invention is to provide a medicinal drug much improved in anti tumor activity and excellent in safety. According to the present invention, there is provided a medicinal drug containing a compound represented by the following general formula (1) or a salt thereof as an active ingredient: [Formula 1] wherein X1 represents a nitrogen atom or a group —CH?, R1 represents a group -Z-R6, in which Z represents a group —CO—, a group —CH(OH)— or the like, R6 represents a 5- to 15-membered monocyclic, dicyclic or tricyclic saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms or sulfur atoms, R2 represents a hydrogen atom or a halogen atom, Y represents a group —O—, a group —CO—, a group —CH(OH)— or a lower alkylene group, and A represents [Formula 2] wherein R3 represents a hydrogen atom, a lower alkoxy group or the like, p represents 1 or 2, R4 represents an imidazolyl lower alkyl group or the like.

Abstract: A non-heat treated seamless steel pipe comprising, by weight, C: 0.10 to 0.25%, Si: 0.05 to 1.00%, Mn: 0.50 to 2.50%, P: not more than 0.03%, S: not more than 0.05%, Cr: 0.40 to 1.50%, Mo: 0.05 to 1.50%, V: 0.02 to 0.30%, Al: 0.003 to 0.10%, B: 0.0003 to 0.01%, and N: 0.001 to 0.02%, in which the balance comprises Fe and impurities. According to this non-heat treated seamless steel pipe, a ferrite area ratio is not more than 10%, and a carbon equivalent Ceq. (%) defined by the following equation is 0.45 to 0.85%. Ceq.

Abstract: The present invention provides a novel compound, which has an excellent effect of suppressing the generation of collagen and less side effects, with being excellent in terms of safety. The compound of the present invention is represented by the following general formula (1): [wherein X1 represents a nitrogen atom or a group —CH?; R1 represents a group -Z-R6, wherein Z represents a group —CO—, a group —CH(OH)—, or the like, and R6 represents a 5- to 15-membered monocyclic, dicyclic, or tricyclic, saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms, or sulfur atoms; R2 represents a hydrogen atom, a halogen atom or a lower alkylene group; Y represents a group —O—, a group —CO—, a group —CH(OH)—, a lower alkylene group, or the like; and A represents a group or the like, wherein R3 represents a hydrogen atom, a lower alkoxy group, or the like, p represents 1 or 2, and R4 represents an imidazolyl lower alkyl group or the like.

Abstract: There is provided a process for producing tofu wherein a delayed action coagulant is dispersed in heated soybean milk in a static inline mixer provided with a narrowed part and then a thickening raw material is added thereto in an inline mixer provided with a dividing element to thereby continuously and efficiently produced a nigari-tofu product being in a good state and having favorable taste.

Abstract: A network system according to the present invention includes a plurality of local area networks (LANs); a wide area network (WAN); a plurality of network bridge devices (CPEs) that connect the LANs to the WAN; and a network management apparatus (OSP) that is connected to the WAN and centrally controls the entire network. The LANs and the WAN both comply with the IEEE 802.3 standard. When receiving a MAC broadcast frame (such as DHCP request and ARP request) from the LANs, the CPEs convert it into a MAC unicast frame, and unicast it to the OSP. As a result, bandwidth saturation of the network due to the explosion or concentration of traffic is prevented.

Abstract: Anon-heat treated seamless steel pipe comprising, by weight, C: 0.10 to 0.25%, Si: 0.05 to 1.00%, Mn: 0.50 to 2.50%, P: not more than 0.03%, S: not more than 0.05%, Cr: 0.40 to 1.50%, Mo: 0.05 to 1.50%, V: 0.02 to 0.30%, Al: 0.003 to 0.10%, B: 0.0003 to 0.01%, and N: 0.001 to 0.02%, in which the balance comprises Fe and impurities. According to this non-heat treated seamless steel pipe, a ferrite area ratio is not more than 10%, and a carbon equivalent Ceq. (%) defined by the following equation is 0.45 to 0.85%. Ceq.

Abstract: A method of efficiently producing foods being free from deformations such as net meshes that would occur when soft hydrous foods are frozen, and having a minimum of cracking to be produced by ice crystal forming. A method of producing soft hydrous foods, wherein soft hydrous foods, upon freezing, are carried to a smooth-flat-surface support, if necessary, by means of a conveyor fitted with crosspieces having upwardly curved surfaces at intervals relative to the conveying surface thereof; they are frozen on the support; and, after starting freezing, they are rolled or transferred onto a different support for further freezing.

Abstract: The present invention provides an optical recording medium containing a phthalocyanine compound in its recording layer and, particularly, a CD-R in which the color of the disk as viewed from the substrate side disappears apparently as if the colorant-containing recording layer were not present Disclosed is an optical recording medium produced by laminating a recording layer, a reflecting layer and a protective layer on the transparent substrate, the recording layer comprising a phthalocyanine compound and a reddish colorant.

Abstract: There is provided a process for producing tofu wherein a delayed action coagulant is dispersed in heated soybean milk in a static inline mixer provided with a narrowed part and then a thickening raw material is added thereto in an inline mixer provided with a dividing element to thereby continuously and efficiently produced a nigari-tofu product being in a good state and having favorable taste.

Abstract: A pyridine derivative represented by formula (1) wherein all the variables have been defined in the specification. The compounds are used for inhibiting collagen production and are useful for preventing or treating fibrosis.

Abstract: The present invention provides an optical recording medium containing a phthalocyanine compound in its recording layer and, particularly, a CD-R in which the color of the disk as viewed from the substrate side disappears apparently as if the colorant-containing recording layer were not present. Disclosed is an optical recording medium produced by laminating a recording layer, a reflecting layer and a protective layer on the transparent substrate, the recording layer comprising a phthalocyanine compound and a reddish colorant.

Abstract: A knock sensor employs a piezoelectric element and includes a ring-shaped weight which has a chamfered surface portion formed at an inner peripheral edge of the weight. The knock sensor basically comprises a housing which includes a disc-shaped flange portion and a cylinder portion covered with an insulating tube. A lower lead plate, the piezoelectric element, an upper lead plate, an insulating sheet, a weight, a disc spring, and a nut are stacked on the flange portion and disposed around the cylinder portion in the order of mention. The nut is tightly screwed to the external thread portion of the cylinder portion to fixedly sandwich the stacked parts with the flange portion of the housing.

Abstract: An optical recording material of the following formula (1) and an optical recording medium excellent in recording sensitivity, light resistance and durability, having a recording layer containing the material,the formula (1), ##STR1## wherein each of X.sub.1 to X.sub.4 is a hydrogen atom, an alkyl group, an aryl group, an alicyclic residue, an aralkyl group, a heterocyclic ring, an alkoxy group, an aryloxy group or an alkylthio group, each of Y.sub.1 to Y.sub.4 is a hydrogen atom, a halogen atom, a nitro group, a phthalimidemethyl group or a sulfoneamide group, each of R.sub.1 and R.sub.2 is a hydrogen atom, a halogen atom, a hydroxyl group, an alkyl group, an aryl group, an aralkyl group, an alkoxy group, an aryloxy group, an alkylthio group, an arylthio group, an alkylamino group, a dialkylamino group, an arylamino group or a diarylamio group, M is Al, Ga, In, Si, Ge or Sn, Z is an azo compound, an anthraquinone compound or a metal complex compound, n.sub.1 to n.sub.4 are 1 to 4, m.sub.1 to m.sub.

Abstract: This invention provides a carbostyril derivative of the formula (1): ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and n are as defined, or its salt. This carbostyril derivative or its salt possess an excellent matrix metalloproteinases inhibitory action.

Abstract: An optical recording medium which has physical and chemical stability, has high sensitivity to laser light and permits accurate recording and highly reliable reproduction. The medium comprises a transparent substrate and a recording layer formed on the substrate, the recording layer being formed of an organic thin layer containing at least one of phthalocyanine compounds of the formula [1].

Abstract: A method for the quantitative determination of polyamines, which comprises allowing a polyamine oxidizing enzyme, an .omega.-aminoalkylaldehyde dehydrogenase, an oxidized nicotinamide coenzyme and, as required, an acylpolyamine anidohydrolase to act upon a sample solution containing polyamines (for example, urine, blood and other kinds of body fluid), and measuring the reduced nicotinamide coenzyme thus formed by, for example, colorimetry, thereby determining the amount of said polyamines.

Abstract: In an integrated circuit comprising a programmable circuit and a non-volatile chip formed on the same chip, a volatile memory, instead of the non-volatile memory, is disposed within the programmable circuit, and a circuit is further provided for transferring program data between the non-volatile memory and the volatile memory. By placing the non-volatile memory outside the programmable circuit, the interior of the programmable circuit is not exposed to the high voltage required for writing to the non-volatile memory, and program data can be rapidly and easily transfered between the memories.

Abstract: A non-volatile memory provides a signal hold circuit which uses a FAMOS instead of an input transistor of a ratiod inverting amplifier and outputs a change in a threshold value of the FAMOS, for the purpose of reducing the number of elements of the signal hold circuit. FAMOSs for programming and latching are provided respectively, and the FAMOSs are interconnected to each other at their floating gate electrodes to isolate the signal hold circuit and a program circuit and hence prevent a DC current path from being formed between those two circuits, for the purpose of miniaturization of a memory cell.

Abstract: There is provided a programmable logic device (PLD) which includes a programmable wiring, the programmable wiring comprising: a plurality of switch stations (SS), first wirings each for directly connecting some terminals among input/output terminals of said SSs to input/output terminals of adjacent programmable logic elements (PLE), and second wirings each for directly connecting some terminals among the input/output terminals of said SSs to input/output terminals of the adjacent SS. Hereby, the numbers of involved switches, through which associated signals pass, can be reduced.

Abstract: A noise suppressing device in a lock device for a vehicle, including a body to be fixed to a door of the vehicle; a latch rotatably supported in the body and adapted to be rotated by engagement with a striker fixed to a vehicle body; a ratchet rotatably supported in the body and adapted to engage a full-latch stepped portion of the latch and thereby prevent reverse rotation of the latch; first and second spring members for biasing the ratchet to engage the same with the latch; and an open lever for releasing engagement of the ratchet with the full-latch stepped portion; wherein the first spring member normally biases the ratchet to engage the same with the latch, and the second spring member does not bias the ratchet under a full-latch condition where the ratchet is engaged with the full-latch stepped portion of the latch, while when the ratchet is rotated in a releasing direction, the second spring member biases the ratchet.