Patents by Inventor Makoto Yanai
Makoto Yanai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240178669Abstract: A vehicle allocation information output apparatus relates to a vehicle capable of supplying electric power to an electric power supply destination, and outputs vehicle allocation information being information relating to the vehicle to be allocated to the electric power supply destination, the apparatus retrieving a route from a current location of the vehicle to the electric power supply destination, calculating a suppliable electric power amount of the vehicle on arrival at the electric power supply destination for the route being retrieved, and outputting information relating to a vehicle allocation pattern in which a consumption electric power amount is minimized as the vehicle allocation information, the vehicle allocation pattern being a vehicle allocation pattern in which a total amount of the suppliable electric power amount of the vehicle to be allocated is equal to or greater than a required electric power amount being required at the electric power supply destination.Type: ApplicationFiled: November 16, 2023Publication date: May 30, 2024Applicant: NEC CorporationInventors: Makoto Iwasaki, Masaru Yanai, Kosei Kobayashi, Hideki Muramatsu, Motoharu Ohtake, Noritsugu Yamanaka
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Publication number: 20240142086Abstract: A lighting device that can switch between intensity distributions of emitted light with a simple configuration. The lighting device includes a light source, a polarization controller, and a polarizing plate, in which the polarization controller switches light emitted from the light source between light components having two or more different polarization states to be incident into the polarizing plate, and the polarizing plate functions as a diffraction grating that has two or more regions having different polarization states of transmitted light in an in-plane direction and where one or more regions among the regions are periodically disposed.Type: ApplicationFiled: December 5, 2023Publication date: May 2, 2024Applicant: FUJIFILM CorporationInventors: Naoki KOITO, Yujiro YANAI, Makoto KAMO, Shinya WATANABE
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Patent number: 7022732Abstract: This invention relates to a medicament containing as an active ingredient, a novel propanolamine having a 1,4-benzodioxane ring or a pharmaceutically acceptable salt thereof: The present compound is represented by the above formula wherein R1-3 may be the same or different and each represents a hydrogen atom, a halogen atom, a hydroxy group, a (C1–C6)alkyl group, a (C1–C6)alkoxy group, a (C1–C6)alkylsulfonamido group, or a phenyl group; R4-5 each represents a hydrogen atom or a (C1–C6)alkyl group; and A represents any of a benzene ring, a pyridine ring and a pyrimidine ring. This compound is useful as a prophylactic or therapeutic agent for diabetes, obesity, hyperlipemia, depression, a respiratory disease, or a gastrointestinal disease.Type: GrantFiled: September 13, 2001Date of Patent: April 4, 2006Assignees: Nisshin Pharma Inc., Kyorin Pharmaceutical Co., Ltd.Inventors: Masahiro Ueno, Koji Kawamura, Makoto Yanai, Toshihiro Takahashi, Nobuhiro Kinoshita, Koichi Katsuyama, Satoko Fuchizawa, Shigeru Hiramoto
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Patent number: 6858585Abstract: Cyclic depsipeptides represented by the formula wherein: R is a straight or branched alkyl group of 5-20 carbon atoms or a straight or branched alkoxymethyl group of 5-15-carbon atoms; A, B, D, E and F independently each other are alanine, valine, leucine, isoleucine, phenylalanine, etc.; W and Z independently each other are aspartic acid, asparagine, glutamic acid or glutamine; and m and n independently each other is 0 or 1, or pharmacologically acceptable salts thereof. The present compounds are prepared according to a method conventionally used in peptide synthesis. The present compounds are useful as an agent for promoting the production of apolipoprotein E, a therapeutic agent for neurologic damages, a therapeutic agent for dementia, an agent for inhibiting the production of apolipoprotein B, an agent for promoting the production of apolipoprotein A1 or a therapeutic agent for hyperlipemia.Type: GrantFiled: June 25, 1997Date of Patent: February 22, 2005Assignee: Nisshin Seifun Group Inc.Inventors: Makoto Yanai, Masashi Suzuki, Norio Oshida, Koji Kawamura, Shigeru Hiramoto, Orie Yasuda, Nobuhiro Kinoshita, Akiko Shingai, Masako Takasu
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Publication number: 20040235921Abstract: This invention relates to a medicament containing as an active ingredient, a novel propanolamine having a 1,4-benzodioxane ring or a pharmaceutically acceptable salt thereof: 1Type: ApplicationFiled: April 21, 2004Publication date: November 25, 2004Inventors: Masahiro Ueno, Koji Kawamura, Makoto Yanai, Toshihiro Takahashi, Nobuhiro Kinoshita, Koichi Katsuyama, Satoko Fuchizawa, Shigeru Hiramoto
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Patent number: 6509482Abstract: Disclosed are optically active alcohols having formulae (1) and (2) wherein R is (R)-1-phenylethylamino or (S)-1-phenylethylamino.Type: GrantFiled: October 18, 2001Date of Patent: January 21, 2003Assignee: Nisshin Pharma Inc.Inventors: Koji Kawamura, Masahiro Ueno, Masashi Suzuki, Makoto Yanai, Toshihiro Takahashi, Koichi Itoh
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Publication number: 20020028957Abstract: Optically active alcohols of formulae (1) and (2) which are useful as intermediates for the synthesis of (RRR)-optical isomers of 1,4-benzodioxin-2-carboxylic acid derivatives which are useful as a prophylactic and therapeutic agent for diabetes, hyperglycemia and the like.Type: ApplicationFiled: October 18, 2001Publication date: March 7, 2002Applicant: Nisshin Pharma Inc.Inventors: Koji Kawamura, Masahiro Ueno, Masashi Suzuki, Makoto Yanai, Toshihiro Takahashi, Koichi Itoh
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Patent number: 6329533Abstract: Disclosed are optically active alcohols having formula (1) and (2) wherein R is (R)-1-phenylethylamino or (S)-1-phenylethylaminoType: GrantFiled: January 22, 2001Date of Patent: December 11, 2001Assignee: Nisshin Pharma Inc.Inventors: Koji Kawamura, Masahiro Ueno, Masashi Suzuki, Makoto Yanai, Toshihiro Takahashi, Koichi Itoh
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Patent number: 6316406Abstract: A depsipeptide containing N-substituted glycine residue having the formula (1) or (2): (wherein R1 is a straight or branched alkyl group of 5-20 carbon atoms or a straight or branched alkoxymethyl group of 5-15 carbon atoms; R2 is a group of the formula —A—B—W—(D)m—(E)n, —A—B—W—(D)m—(E)n—F or —A—B—W—(D)m—(E)n—F—Z; R3 is a hydroxyl group, a lower alkoxy group, a benzyloxy group, or a group of the formula —Z, —Z—G or —Z—G—J; A, B, D, E, F, G and J independently are an N-substituted glycine residue or a residue of an amino acid selected from the group consisting of alanine, valine, leucine, serine, etc.; W and Z independently are a residue of an amino acid selected from the group consisting of an aspartic acid, a glutamic acid, etc.Type: GrantFiled: August 24, 1999Date of Patent: November 13, 2001Assignee: Nisshin Seifun Group Inc.Inventors: Makoto Yanai, Masashi Suzuki, Norio Oshida, Koji Kawamura, Shigeru Hiramoto, Orie Yasuda, Nobuhiro Kinoshita, Akiko Shingai, Masako Takasu
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Patent number: 6288038Abstract: The present invention provides a new depsipeptide derivative having a piperazinone ring within the molecule which is represented by formula (1) wherein X1 represents N(R4)—CO, N(R5)—CH2, CH2—CO, CH2—CH2, CH═CH, CH2—CH(OH) or CH(OH)—CH(OH), R1 represents a C5-C20 alkyl group or a C5-C15 alkoxy C1-C4 alkyl group, R2-R5 represent a hydrogen atom or a C1-C6 alkyl group, and A represents a group of formula (2), (3) or (4) The depsipeptide derivative has a function of accelerating the production of apolipoprotein E and is useful as an agent for the treatment of neurologic injury, an agent for the treatment of dementia and an antihyperlipidemic agent.Type: GrantFiled: April 3, 2000Date of Patent: September 11, 2001Assignee: Nisshin Seifun Group Inc.Inventors: Makoto Yanai, Masashi Suzuki, Norio Oshida, Koji Kawamura, Shigeru Hiramoto, Orie Yasuda, Nobuhiro Kinoshita, Akiko Shingai, Masako Takasu
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Publication number: 20010018529Abstract: Optically active alcohols of formulae (1) and (2) which are useful as intermediates for the synthesis of (RRR)-optical isomers of 1,4-benzodioxin-2-carboxylic acid derivatives which are useful as a prophylactic and therapeutic agent for diabetes, hyperglycemia and the like.Type: ApplicationFiled: January 22, 2001Publication date: August 30, 2001Applicant: Nisshin Flour Milling Co., Ltd.Inventors: Koji Kawamura, Masahiro Ueno, Masashi Suzuki, Makoto Yanai, Toshihiro Takahashi, Koichi Itoh
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Patent number: 6255286Abstract: Depsipeptides represented by the formula (1): (wherein: R1 is a straight or branched alkyl group of 5-20 carbon atoms or a straight or branched alkoxymethyl group of 5-15 carbon atoms; R2 is —A—B, —A—B—W, —A—B—W—D or —A—B—W—D—E, R3 is a hydroxyl group, a lower alkoxy group, a benzyloxy group, —Z, —Z—G or —Z—G—J, the above A, B, D, E, G and J independently each other are a residue of an amino acid selected from alanine, valine, leucine, isoleucine, serine, threonine, lysine, hydroxylysine, arginine, cysteine, methionine, phenylalanine, tyrosine, aspartic acid, asparagine, glutamic acid, glutamine and the like or an N—(C1-C4) alkyl derivative of these amino acid residues; the above W and Z independently each other are a residue of an amino acid selected from aspartic acid, asparagine, glutamic acid, glutamine, alanine, serine or lysine) or pharmacologically acceptableType: GrantFiled: December 24, 1998Date of Patent: July 3, 2001Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Makoto Yanai, Masashi Suzuki, Norio Oshida, Koji Kawamura, Shigeru Hiramoto, Orie Yasuda, Nobuhiro Kinoshita, Akiko Shingai, Masako Takasu
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Patent number: 6252041Abstract: A depsipeptide containing a non-natural amino acid(s) having the formula (1) wherein R1 represents a C5-C20 alkyl group and others; R2 represents —O—CO—CH(R5)—X—CH(R6)—NH— (wherein X represents N(R7)—CO, CH2—CO, CH2—CH2 and others, R5, R6, and R7 represent a hydrogen atom or a C1-C6 alkyl group); R3 represents and wherein the remaining substituent variables are as defined herein. The above depsipeptides have a promoting activity on the production of apolipoprotein E, and are useful as a therapeutic agent for neurologic damages, especially dementia, and hyperlipemia.Type: GrantFiled: January 22, 1999Date of Patent: June 26, 2001Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Makoto Yanai, Masashi Suzuki, Norio Oshida, Koji Kawamura, Shigeru Hiramoto, Orie Yasuda, Nobuhiro Kinoshita, Akiko Shingai, Masako Takasu
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Patent number: 6222050Abstract: Disclosed are optically active alcohols having formula (1) and (2) wherein R is (R)-1-phenylethylamino or (S)-1-phenylethylamino. The active alcohols can be prepared by acylating a racemate of formula (3) in the presence of a hydrolase, followed by alcoholysis or hydrolysis. R in formula (3) is the same as that defined for formula (1) and (2).Type: GrantFiled: March 23, 2000Date of Patent: April 24, 2001Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Koji Kawamura, Masahiro Ueno, Masashi Suzuki, Makoto Yanai, Toshihiro Takahashi, Koichi Itoh
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Patent number: 6211145Abstract: The present invention provides a bicyclic depsipeptide having the formula (1) wherein: R is a straight or branched alkyl group of 5-20 carbon atoms or a straight or branched alkoxymethyl group of 5-15 carbon atoms; A, D, E and J independently are a residue of an amino acid selected from the group of alanine, valine, leucine, etc.; B and F are the same or different and a residue of an amino acid selected from the group consisting of cysteine, aspartic acid, glutamic acid, lysine, hydroxylysine and serine; G is a disulfide bond, an amido bond or an ester bond; W is a residue of an amino acid selected from the group consisting of aspartic acid and glutamic acid; Z is a residue of an amino acid selected from the group consisting of aspartic acid, asparagine, glutamic acid and glutamine; l, m, n, p and q independently are 0 or 1; or a pharmacologically acceptable salt thereof.Type: GrantFiled: December 16, 1998Date of Patent: April 3, 2001Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Makoto Yanai, Masashi Suzuki, Norio Oshida, Koji Kawamura, Shigeru Hiramoto, Orie Yasuda, Nobuhiro Kinoshita, Akiko Shingai, Masako Takasu
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Patent number: 6011069Abstract: There is disclosed a multidrug resistance inhibitor for overcoming a multidrug resistance of cancer, or an agent for enhancing the activity of anti-cancer agents, which comprises as an active ingredient a compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein n is an integer of 5 to 12,R.sub.1 and R.sub.2 are each independently benzyl, of which a phenyl ring may be substituted by 1 to 5 substituents selected from hydroxy, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy and halogen, and/or by methylenedioxy, with the proviso that R.sub.1 and R.sub.Type: GrantFiled: December 17, 1996Date of Patent: January 4, 2000Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Kohei Inomata, Toshihiro Takahashi, Hitoshi Inoue, Makoto Yanai, Hiroyuki Yamazaki, Masashi Suzuki, Tsutomu Takasawa, Kouji Kawamura, Norio Oshida, Hiroyuki Ikemoto, Takao Kishiye
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Patent number: 6001815Abstract: A depsipeptide containing N-substituted glycine residue having the formula (1) or (2): ##STR1## (wherein R.sub.1 is a straight or branched alkyl group of 5-20 carbon atoms or a straight or branched alkoxymethyl group of 5-15 carbon atoms; R.sub.2 is a group of the formula --A--B--W--(D).sub.m --(E).sub.n, --A--B--W--(D).sub.m --(E).sub.n --F or --A--B--W--(D).sub.m --(E).sub.n --F--Z; R.sub.3 is a hydroxyl group, a lower alkoxy group, a benzyloxy group, or a group of the formula --Z, --Z--G or --Z--G--J; A, B, D, E, F, G and J independently are an N-substituted glycine residue or a residue of an amino acid selected from the group consisting of alanine, valine, leucine, serine, etc.; W and Z independently are a residue of an amino acid selected from the group consisting of an aspartic acid, a glutamic acid, etc.; at least one of A, B, D, E, F, G and J is an N-substituted glycine residue) or a pharmacologically acceptable salt thereof.Type: GrantFiled: December 21, 1998Date of Patent: December 14, 1999Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Makoto Yanai, Masashi Suzuki, Norio Oshida, Koji Kawamura, Shigeru Hiramoto, Orie Yasuda, Nobuhiro Kinoshita, Akiko Shingai, Masako Takasu
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Patent number: 5756475Abstract: Isoprene derivatives of formula (I) ##STR1## wherein m is an integer of 0 to 3,n is an integer of 5 to 12,A is cyclo(C.sub.3 -C.sub.6)alkylene, phenylene, fluorenylene, pyrrolidinylene, piperazinylene, 9-aza-3-oxabicyclo?3.3.1!-nonylene,R.sub.1 and R.sub.2 are each independently benzyl, of which a phenyl ring may be substituted by 1 to 5 substituents selected from the group consisting of hydroxy, (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy and halogen,X is a single bond or a divalent radical of --(CH.sub.2).sub.p NH--,p is an integer of 0 to 3, or a pharmaceutically acceptable salt thereof. Those compounds are useful as multidrug resistance inhibitors for overcoming multidrug resistance of cancer and agents for enhancing an activity of anti-cancer agents.Type: GrantFiled: January 30, 1997Date of Patent: May 26, 1998Assignee: Nisshin Flour Milling Co., Ltd.Inventors: Kohei Inomata, Toshihiro Takahashi, Hitoshi Inoue, Makoto Yanai, Hiroyuki Yamazaki, Masashi Suzuki, Tsutomu Takasawa, Kouji Kawamura, Norio Oshida, Hiroyuki Ikemoto, Takao Kishiye
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Patent number: D513026Type: GrantFiled: March 1, 2004Date of Patent: December 20, 2005Assignee: Nikon CorporationInventors: Makoto Yanai, Takashi Kishigami, Eiji Takenaka, Nobuo Hashimoto
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Patent number: D523884Type: GrantFiled: November 17, 2003Date of Patent: June 27, 2006Assignee: Nikon CorporationInventors: Makoto Yanai, Hiroshi Kobayashi