Abstract: Disclosed herein an anti-pT217 Tau antibody or a pT217 Tau-binding fragment thereof.

Abstract: A system for use in preventing a flow of gas from a gas-containing region (20) to an adjacent region (22) and/or for collecting or dispersing gas at the interface between the regions, comprising a composite barrier (10) installed so as to separate the two regions (20, 22), the barrier (10) comprising a gas-impermeable layer (11) and a gas-permeable membrane (12) interconnected so as to define an interspace (16) between them and arranged with the permeable layer (12) facing the region containing gas (20) to be dispersed or collected. A method is also described comprising the steps of connecting an aperture (36) or aperture of the barrier communicating with the interspace (16) thereof to pumping means (37) which, in operation, act to pump gas into or out from the interspace (16) by creating a pressure differential across the permeable membrane such as to cause gas to flow therethrough across a major proportion of its surface area.

Abstract: The present invention is related to providing a non-infectious molecular clone of a mutant HIV and HIV proteins useful as immunogens and reagents for diagnostic kit.

Abstract: Leu-3.sup.- cells surviving infection with the AIDS retrovirus can be induced with IUdR to express infectious virus. A cellular clone (8E5), isolated by limiting dilution of a mass culture of survivor cells, was found to contain a single, integrated, defective provirus that was consitutively expressed. Although IUdR treatment of 8E5 cells failed to induce infectious virus, cocultivation with Leu-3.sup.+ generated the characteristic syncytia associated with acute AIDS retrovirus infention. The single integrated copy of proviral DNA directs the synthesis of all major viral structural proteins except p64 and p34 as monitored by immunoblotting. Diagnostic reagents and kits in accordance with the present invention are also described.