Abstract: A method for inhalation of a dry powder drug includes the steps of providing a dry powder drug composition having a drug particle size of from about 1-7 microns and a mass median aerodynamic diameter of the delivered aerosol of from about 3.5 to 5.5 microns. This composition is loaded into an inhaler which is generally flow rate independent, and with the inhaler having an inspiration flow resistance of about 0.12 to 0.21 (cmH.sub.2 O).sup.1/2 over the range of about 15-60 L/min. The patient inhales the drug composition from the inhaler with an inspiration flow rate of about 15-60 L/min, resulting in a delivery efficiency measured by respirable fraction greater than 20%.

Abstract: In a method for treating lung diseases, a drug formulation is prepared by combining micronized crystalline beclomethasone dipropionate and lactose. The drug formulation is placed into a dry powder inhaler which provides inhalable drug particles having a mass median diameter of about 0.5-5.8 microns. The inhaler is preferably largely flow rate independent. Drug and lactose particles are separated in the inhaler during inhalation, most desirably via a spinning element. Due to deep deposition, the drug particles persist in the lungs for a surprisingly long duration, increasing the therapeutic effect of each dose. The patient inhales the drug particles with an inspiratory flow rate of about 10-60 liters/minute, to produce a deep lung deposition of inhaled particles.

Abstract: In a process for cooling hot rolled metal plates (16) and strips, especially such of aluminium or an aluminium alloy, a hot rolled strip (12) is cut to plates (16) immediately after it emerges from a rolling mill (10). Immediately after the cutting to length, the plates (16) pass through a cooling station (20) where they are jetted directly with water from flat stream nozzles (52). The water stream (W) emerging from the flat stream nozzles (52) form essentially a plane (E) which is directed at the plate surface (32). Immediately after it leaves the flat stream nozzle (52), the water stream (W) is periodically deflected by means of streams (A, B) of air or water in such a manner that the water stream (W) striking the plate surface (32) performs a wiping action.