Patents by Inventor Malcolm Low

Malcolm Low has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modification of feeding behavior
    Patent number: 8217001
    Abstract: Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering a therapeutically effective amount of PYY or an agonist thereof to the subject, thereby decreasing the calorie intake of the subject.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: July 10, 2012
    Inventors: Michael Cowley, Roger Cone, Malcolm Low, Andrew Butler, Stephen Robert Bloom, Caroline Jane Small, Rachel Louise Batterham, Mohammad Ali Ghatei
  • Method for screening for agents that affect food intake
    Patent number: 7919329
    Abstract: Screening methods of use in identifying agents that affect caloric intake, food intake, appetite, and energy expenditure are disclosed herein. These methods are used to identify agents of use in treating obesity, or that can be used to decrease the weight of a subject. These methods can also be used to identify agents of use in treating anorexia or cachexia and can be used to increase appetite and to increase the weight and lean body mass of a subject.
    Type: Grant
    Filed: January 24, 2008
    Date of Patent: April 5, 2011
    Assignee: Oregon Health & Science University
    Inventors: Michael Cowley, Roger Cone, Malcolm Low, Andrew Butler
  • MODIFICATION OF FEEDING BEHAVIOR
    Publication number: 20090209461
    Abstract: Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering a therapeutically effective amount of PYY or an agonist thereof to the subject, thereby decreasing the calorie intake of the subject.
    Type: Application
    Filed: August 29, 2008
    Publication date: August 20, 2009
    Applicants: Imperial College Innovations Ltd., Oregon Health and Science University
    Inventors: Michael Cowley, Roger Cone, Malcolm Low, Andrew Butler, Stephen Robert Bloom, Caroline Jane Small, Rachel Louise Batterham, Mohammad Ali Ghatei
  • Modification of feeding behavior
    Patent number: 7459432
    Abstract: Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering a therapeutically effective amount of PYY or an agonist thereof to the subject, thereby decreasing the calorie intake of the subject.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: December 2, 2008
    Assignees: Imperial College Innovations Ltd., Oregon Health and Science University
    Inventors: Michael Cowley, Roger Cone, Malcolm Low, Andrew Butler, Stephen Robert Bloom, Caroline Jane Small, Rachel Louise Batterham, Mohammad Ali Ghatel
  • ASSESSMENT OF NEURONS IN THE ARCUATE NUCLEUS TO SCREEN FOR AGENTS THAT MODIFY FEEDING BEHAVIOR
    Publication number: 20080213803
    Abstract: Screening methods of use in identifying agents that affect caloric intake, food intake, appetite, and energy expenditure are disclosed herein. These methods are used to identify agents of use in treating obesity, or that can be used to decrease the weight of a subject. These methods can also be used to identify agents of use in treating anorexia or cachexia and can be used to increase appetite and to increase the weight and lean body mass of a subject.
    Type: Application
    Filed: January 24, 2008
    Publication date: September 4, 2008
    Inventors: Michael Cowley, Roger Cone, Malcolm Low, Andrew Butler
  • Upstream control elements of the proopiomelanocortin gene and their use
    Publication number: 20070059797
    Abstract: The nucleic acid sequence of the POMC enhancer is disclosed herein. Sequences from the human, rat, rabbit, hamster, mouse, and cow POMC enhancer are disclosed. Hybrid transgenes, comprising a POMC transcriptional control element operably linked to a nucleic acid sequence encoding a marker are also enclosed. In addition, transgenic mice carrying a hybrid transgene including a POMC control element operably linked to a marker are disclosed herein.
    Type: Application
    Filed: August 10, 2006
    Publication date: March 15, 2007
    Inventors: Malcolm Low, Marcelo Rubinstein, Flavio de Souza
  • Modification of feeding behavior
    Publication number: 20060014678
    Abstract: Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering PYY or an agonist thereof and GLP-1 or an agonist thereof to the subject, simultaneously or sequentially, thereby decreasing the calorie intake of the subject.
    Type: Application
    Filed: January 10, 2003
    Publication date: January 19, 2006
    Inventors: Michael Cowley, Roger Cone, Malcolm Low, Andrew Butler, Stephen Bloom, Caroline Small, Rachel Batterham, Mohammed Ghatei
  • Modification of feeding behavior
    Publication number: 20050176630
    Abstract: Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering a therapeutically effective amount of PYY or an agonist thereof to the subject, thereby decreasing the calorie intake of the subject.
    Type: Application
    Filed: September 24, 2002
    Publication date: August 11, 2005
    Inventors: Michael Cowley, Roger Cone, Malcolm Low, Andrew Butler, Stephen Bloom, Caroline Small, Rachel Batterham, Mohammad Ghatel
  • Assessment of neurons in the arcuate nucleus to screen for agents that modify feeding behavior
    Publication number: 20050015820
    Abstract: Screening methods of use in identifying agents that affect caloric intake, food intake, appetite, and energy expenditure are disclosed herein. These methods are used to identify agents of use in treating obesity, or that can be used to decrease the weight of a subject. These methods can also be used to identify agents of use in treating anorexia or cachexia and can be used to increase appetite and to increase the weight and lean body mass of a subject.
    Type: Application
    Filed: September 24, 2002
    Publication date: January 20, 2005
    Inventors: Michael Cowley, Roger Cone, Malcolm Low, Andrew Butler