Patents by Inventor Malcolm Moore

Malcolm Moore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200246284
    Abstract: Method of using ureidomustine (BO-1055), a water-soluble NDA cross-linking agent, in the treatment of small lung cell carcinoma (SCLC).
    Type: Application
    Filed: January 30, 2020
    Publication date: August 6, 2020
    Inventors: Malcolm Moore, Jae-Hung Shieh, Tsann-Long Su, Te-Chang Lee
  • Patent number: 10548861
    Abstract: Method of using ureidomustine (BO-1055), a water-soluble NDA cross-linking agent, in the treatment of a cancer, selected from the group consisting of various types of human leukemia [such as acute myeloid leukemia (ALL) and acute B Lymphoblastic leukemia (B-ALL)], lymphomas, small lung cell carcinoma (SCLC), sarcomas, and others.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: February 4, 2020
    Assignees: Academia Sinica, Memorial Sloan Kettering Cancer Center
    Inventors: Malcolm Moore, Jae-Hung Shieh, Tsann-Long Su, Te-Chang Lee
  • Publication number: 20190008808
    Abstract: Method of using ureidomustine (BO-1055), a water-soluble NDA cross-linking agent, in the treatment of a cancer, selected from the group consisting of various types of human leukemia [such as acute myeloid leukemia (ALL) and acute B Lymphoblastic leukemia (B-ALL)], lymphomas, small lung cell carcinoma (SCLC), sarcomas, and others.
    Type: Application
    Filed: August 17, 2016
    Publication date: January 10, 2019
    Inventors: Malcolm Moore, Jae-Hung Shieh, Tsann-Long Su, Te-Chang Lee
  • Patent number: 9546146
    Abstract: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: January 17, 2017
    Assignee: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
    Inventors: Samuel J. Danishefsky, Joan Massague, Manuel Valiente Cortes, Thordur Oskarsson, Malcolm Moore, Nicolas Lecomte, Ouathek Ouerfelli, Guangli Yang
  • Publication number: 20160221984
    Abstract: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
    Type: Application
    Filed: March 9, 2016
    Publication date: August 4, 2016
    Inventors: Samuel J. Danishefsky, Joan Massague, Manuel Valiente Cortes, Thordur Oskarsson, Malcolm Moore, Nicolas Lecomte, Ouathek Ouerfelli, Guangli Yang
  • Patent number: 9029403
    Abstract: Methods for inhibiting the growth of ovarian cancer cells or other serosal cancer cells are disclosed. The method involves exposing the cells to a benzylidinebenzohydrazide of formula: wherein X is carbon or nitrogen.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: May 12, 2015
    Assignee: Memorial Sloan-Kettering Cancer Center
    Inventors: Malcolm Moore, Server A. Ertem
  • Publication number: 20140315959
    Abstract: Methods for inhibiting the growth of ovarian cancer cells or other serosal cancer cells are disclosed. The method involves exposing the cells to a benzylidinebenzohydrazide of formula: wherein X is carbon or nitrogen.
    Type: Application
    Filed: November 9, 2012
    Publication date: October 23, 2014
    Inventors: Malcolm Moore, Server A. Ertem
  • Publication number: 20140275174
    Abstract: Methods for inhibiting the growth of ovarian cancer cells or other serosal cancer cells are disclosed. The method involves exposing the cells to a 2-amino-4H-naphtho[1,2-b]pyran-3-carbonitrile of formula: whereinY is CR1 or N and Z is CR5 or N.
    Type: Application
    Filed: November 9, 2012
    Publication date: September 18, 2014
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Malcolm Moore, Server A. Ertem
  • Publication number: 20050276784
    Abstract: A pharmaceutical composition which comprises the c-kit ligand (KL) purified by applicants or produced by applicants' recombinant methods in combination with other hematopoietic factors and a pharmaceutically acceptable carrier is provided as well as methods of treating patients which comprise administering to the patient the pharmaceutical composition of this invention. This invention provides combination therapies using c-kit ligand (KL) and a purified c-kit ligand (KL) polypeptide, or a soluble fragment thereof and other hematopoietic factors. It also provides methods and compositions for ex-vivo use of KL alone or in combination therapy. A mutated KL antagonist is also described. Such an antagonist may also be a small molecule. Antisense nucleic acids to KL as therapeutics are also described. Lastly, compositions and methods are described that take advantage of the role of KL in germ cells, mast cells and melanocytes.
    Type: Application
    Filed: November 12, 2004
    Publication date: December 15, 2005
    Inventors: Peter Besmer, Jochen Buck, Malcolm Moore, Karl Nocka
  • Publication number: 20050143429
    Abstract: The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).
    Type: Application
    Filed: August 18, 2004
    Publication date: June 30, 2005
    Inventors: Samuel Danishefsky, Alexey Rivkin, Fumihiko Yoshimura, Ting-Chao Chou, Ana Gabarda, Huajin Dong, Kaida Wu, Malcolm Moore, David Dorn
  • Publication number: 20050142659
    Abstract: The invention is directed to a purified population of mammalian endothelial, muscle, or neural stem cells. The invention further provides methods for isolating such populations of cells; methods for using such populations of cells for treating mammals; methods for making vectors for gene therapy; and methods for carrying out gene therapy with such vectors.
    Type: Application
    Filed: December 16, 2004
    Publication date: June 30, 2005
    Inventors: Shahin Rafii, Larry Witte, Malcolm Moore
  • Publication number: 20050063946
    Abstract: Highly purified Pluripotent hematopoietic colony-stimulating factor (pluripotent CSF), a glycoprotein (MW 19,600) constitutively produced by human tumor cells has been highly purified from low serum-containing conditioned medium to apparant homogeneity. Pluripotent CSF supports the growth of human mixed colonies (CFU-GEMM), granulocyte-macrophage colonies (CFU-GM), early erythroid colonies (BFU-E) and induces differentiation of human leukemic cells. The specific activity of the purified pluripotent CSF in the CFU-GM assay is 1.5×108 U/mg protein.
    Type: Application
    Filed: October 5, 2004
    Publication date: March 24, 2005
    Inventors: Karl Welte, Erich Platzer, Janice Gabrilove, Roland Mertelsmann, Malcolm Moore
  • Patent number: 5560519
    Abstract: Each dispenser, which may be used for candy, is identical except for a identically sized top rectangular panel. The back, bottom, front, and a baffle are formed of one piece of thermoplastic material. A right angle bent is adhered to the top of the baffle. The top panels for a top row of dispensers are adhered to the dispensers and each has a hole communicating with a cylindrical reservoir. Those for a bottom row are hinged to the back. All sides are identical. Depending chutes are rectangular and have a sliding door. The sliding doors and the bent each have identical cylinders adhered to them. The walls of each chute have holes aligned with its cylinder. The hinged tops have a hole through which a cylinder protrudes. A locking cable has a large finial at one end and a small finial at the other. Two washers are provided that fit over the large finial, but not the smaller. A washer is threaded against the large finial and the cable passed through aligned cylinders.
    Type: Grant
    Filed: January 10, 1994
    Date of Patent: October 1, 1996
    Assignee: Clearview Industries, Inc.
    Inventors: Malcolm A. Moore, Robert H. Schmidt
  • Patent number: 5005335
    Abstract: An article stack unifying device having article stacking elements is provided to stack a plurality of articles on a surface on or of a rotatable surface. While the articles are being stacked on the selected surface a quantity of wrapping film is wrapped around the stack of articles at intervals during the stacking process and at the completion of the stack.
    Type: Grant
    Filed: December 5, 1989
    Date of Patent: April 9, 1991
    Assignee: FMC Corporation
    Inventors: Ray A. Yourgalite, Malcolm Moore, Neal C. Chamberlain, Kenneth F. Becicka, Samuel J. Hilgeman, Kevin D. Moore
  • Patent number: 4995224
    Abstract: An article stack unifying device having article stacking elements is provided to stack a plurality of articles on a surface on or of a rotatable surface. While the articles are being stacked on the selected surface a quantity of wrapping film is wrapped around the stack of articles at intervals during the stacking process and at the completion of the stack.
    Type: Grant
    Filed: December 5, 1989
    Date of Patent: February 26, 1991
    Assignee: FMC Corporation
    Inventors: Ray A. Yourgalite, Malcolm Moore, Neal C. Chamberlain, Kenneth F. Becicka, Samuel J. Hilgeman, Kevin D. Moore
  • Patent number: 4213699
    Abstract: A laser beam is transmitted through a medium containing the component to be measured. The wavelength of the beam is such that it is absorbed by the component but not by the remainder of the medium. The divergence of the beam is measured to indicate a change in the index of refraction of the medium due to the absorption by the component.
    Type: Grant
    Filed: February 27, 1976
    Date of Patent: July 22, 1980
    Assignee: s.a. Texaco Belgium n.v.
    Inventor: Malcolm Moore