Patents by Inventor Malcolm Osborne

Malcolm Osborne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132965
    Abstract: Described herein is a method for detecting cancer DNA in a test sample of DNA from a patient. In some embodiments, the method may comprise: (a) sequencing multiple aliquots of the test sample to produce, for each aliquot, sequence reads corresponding to two or more target regions that each have one or more sequence variations present within the patient's cancer; (b) for each aliquot, for each target region: i. determining the number of sequence reads that have the sequence variation; ii. determining the total number of sequence reads; and iii. comparing i. and ii. to one or more error probability distribution models for the sequence variation, wherein the one or more models are obtained from DNA that does not contain the sequence variation; and (c) integrating the collective results of step (b) to determine if there is cancer DNA in the test sample.
    Type: Application
    Filed: February 2, 2023
    Publication date: April 25, 2024
    Inventors: Malcolm PERRY, Giovanni MARSICO, Robert OSBORNE, Nitzan ROSENFELD, Tim FORSHEW
  • Patent number: 5121842
    Abstract: A vertical post mounted to a base in an orthogonal relationship includes plural columns of clip members, with each clip member arranged to mount a cap thereto for display and organization of a plurality of such cap members. A modification of the invention includes flexible alignment rods wound about a spool within the post adjacent each clip projecting through an opening in the post aligned with an upper terminal end of each clip to provide underlying support for a cap member assocated with each clip. The alignment rods are retractably contained within the post when not in use.
    Type: Grant
    Filed: July 12, 1991
    Date of Patent: June 16, 1992
    Inventor: Malcolm Osborne