Patents by Inventor Maling GOU

Maling GOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Liver-mimetic device and method for simulation of hepatic function using such device
    Patent number: 10954489
    Abstract: A liver-mimetic device and method include a 3D polymer scaffold having a matrix of liver-like lobules with hepatic-functioning particles encapsulated within the lobules. In some embodiments, each liver-like lobule is hexagonal in structure and the matrix is in a honeycomb arrangement. In some embodiments, the hepatic-functioning particles are hepatic progenitor cells. In other embodiments, the hepatic-functioning particles are polymer nanoparticles adapted to capture pore-forming toxins.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: March 23, 2021
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS)
    Inventors: Xin Qu, Maling Gou, Wei Zhu, Shaochen Chen
  • LIVER-MIMETIC DEVICE AND METHOD FOR SIMULATION OF HEPATIC FUNCTION USING SUCH DEVICE
    Publication number: 20160298087
    Abstract: A liver-mimetic device and method include a 3D polymer scaffold having a matrix of liver-like lobules with hepatic-functioning particles encapsulated within the lobules. In some embodiments, each liver-like lobule is hexagonal in structure and the matrix is in a honeycomb arrangement. In some embodiments, the hepatic-functioning particles are hepatic progenitor cells. In other embodiments, the hepatic-functioning particles are polymer nanoparticles adapted to capture pore-forming toxins.
    Type: Application
    Filed: June 4, 2014
    Publication date: October 13, 2016
    Inventors: Xin QU, Maling GOU, Wei ZHU, Shaochen CHEN