Patents by Inventor Mami Yamazaki
Mami Yamazaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9051255Abstract: To find a therapeutic and/or prophylactic agent for gastrointestinal disorders and so on, the agent having excellent activity and high safety. A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof. In the formula, A represents an optionally substituted phenylene group; B represents an optionally substituted 4- to 10-membered heterocyclic group, an optionally substituted C6-C10 aryl group, or an optionally substituted C3-C10 cycloalkyl group; R1 represents a hydrogen atom or a C1-C3 alkyl group; R2 represents a hydrogen atom or a C1-C3 alkyl group; R3 represents a C1-C6 alkyl group, a C3-C10 cycloalkyl group, a C1-C3 alkoxy C1-C3 alkyl group, or a C1-C3 hydroxyalkyl group; R4 represents a hydrogen atom, a C1-C6 alkyl group, or a halogen atom; n represents an integer of 1 to 4; and X represents methylene, —O—, —NH—, —N(C1-C3 alkyl)-, —C(?O)—, —S—, —S(O)—, —S(O2)—, or a single bond.Type: GrantFiled: December 27, 2013Date of Patent: June 9, 2015Assignee: Daiichi Sankyo Company, LimitedInventors: Narihiro Toda, Rieko Takano, Takeshi Shida, Takahiro Katagiri, Mitsuhiro Iwamoto, Shinji Ashida, Mami Yamazaki
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Publication number: 20140221391Abstract: To find a therapeutic and/or prophylactic agent for gastrointestinal disorders and so on, the agent having excellent activity and high safety. A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof. In the formula, A represents an optionally substituted phenylene group; B represents an optionally substituted 4- to 10-membered heterocyclic group, an optionally substituted C6-C10 aryl group, or an optionally substituted C3-C10 cycloalkyl group; R1 represents a hydrogen atom or a C1-C3 alkyl group; R2 represents a hydrogen atom or a C1-C3 alkyl group; R3 represents a C1-C6 alkyl group, a C3-C10 cycloalkyl group, a C1-C3 alkoxy C1-C3 alkyl group, or a C1-C3 hydroxyalkyl group; R4 represents a hydrogen atom, a C1-C6 alkyl group, or a halogen atom; n represents an integer of 1 to 4; and X represents methylene, —O—, —NH—, —N(C1-C3 alkyl)-, —C(?O)—, —S—, —S(O)—, —S(O2)—, or a single bond.Type: ApplicationFiled: December 27, 2013Publication date: August 7, 2014Applicant: DAIICHI SANKYO COMPANY, LIMITEDInventors: Narihiro Toda, Rieko Takano, Takeshi Shida, Takahiro Katagiri, Mitsuhiro Iwamoto, Shinji Ashida, Mami Yamazaki
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Publication number: 20140221392Abstract: To find a therapeutic and/or prophylactic agent for gastrointestinal disorders and so on, the agent having excellent activity and high safety. A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof. In the formula, A represents an optionally substituted phenylene group; B represents an optionally substituted 4- to 10-membered heterocyclic group, an optionally substituted C6-C10 aryl group, or an optionally substituted C3-C10 cycloalkyl group; R1 represents a hydrogen atom or a C1-C3 alkyl group; R2 represents a hydrogen atom or a C1-C3 alkyl group; R3 represents a C1-C6 alkyl group, a C3-C10 cycloalkyl group, a C1-C3 alkoxy C1-C3 alkyl group, or a C1-C3 hydroxyalkyl group; R4 represents a hydrogen atom, a C1-C6 alkyl group, or a halogen atom; n represents an integer of 1 to 4; and X represents methylene, —O—, —NH—, —N(C1-C3 alkyl)-, —C(?O)—, —S—, —S(O)—, —S(O2)—, or a single bond.Type: ApplicationFiled: December 27, 2013Publication date: August 7, 2014Applicant: DAIICHI SANKYO COMPANY, LIMITEDInventors: Narihiro Toda, Rieko Takano, Takeshi Shida, Takahiro Katagiri, Mitsuhiro Iwamoto, Shinji Ashida, Mami Yamazaki
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Patent number: 8710060Abstract: To find a therapeutic and/or prophylactic agent for gastrointestinal disorders and so on, the agent having excellent activity and high safety. A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof. In the formula, A represents an optionally substituted phenylene group; B represents an optionally substituted 4- to 10-membered heterocyclic group, an optionally substituted C6-C10 aryl group, or an optionally substituted C3-C10 cycloalkyl group; R1 represents a hydrogen atom or a C1-C3 alkyl group; R2 represents a hydrogen atom or a C1-C3 alkyl group; R3 represents a C1-C6 alkyl group, a C3-C10 cycloalkyl group, a C1-C3 alkoxy C1-C3 alkyl group, or a C1-C3 hydroxyalkyl group; R4 represents a hydrogen atom, a C1-C6 alkyl group, or a halogen atom; n represents an integer of 1 to 4; and X represents methylene, —O—, —NH—, —N(C1-C3 alkyl)-, —C(?O)—, —S—, —S(O)—, —S(O2)—, or a single bond.Type: GrantFiled: March 26, 2013Date of Patent: April 29, 2014Assignee: Daiichi Sankyo Company, LimitedInventors: Narihiro Toda, Rieko Takano, Takeshi Shida, Takahiro Katagiri, Mitsuhiro Iwamoto, Shinji Ashida, Mami Yamazaki
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Publication number: 20130289048Abstract: To find a therapeutic and/or prophylactic agent for gastrointestinal disorders and so on, the agent having excellent activity and high safety. A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof. In the formula, A represents an optionally substituted phenylene group; B represents an optionally substituted 4- to 10-membered heterocyclic group, an optionally substituted C6-C10 aryl group, or an optionally substituted C3-C10 cycloalkyl group; R1 represents a hydrogen atom or a C1-C3 alkyl group; R2 represents a hydrogen atom or a C1-C3 alkyl group; R3 represents a C1-C6 alkyl group, a C3-C10 cycloalkyl group, a C1-C3 alkoxy C1-C3 alkyl group, or a C1-C3 hydroxyalkyl group; R4 represents a hydrogen atom, a C1-C6 alkyl group, or a halogen atom; n represents an integer of 1 to 4; and X represents methylene, —O—, —NH—, —N(C1-C3 alkyl)-, —C(?O)—, —S—, —S(O)—, —S(O2)—, or a single bond.Type: ApplicationFiled: March 26, 2013Publication date: October 31, 2013Inventors: Narihiro Toda, Rieko Takano, Takeshi Shida, Takahiro Katagiri, Mitsuhiro Iwamoto, Shinji Ashida, Mami Yamazaki
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Patent number: 7501271Abstract: The present invention provides a gene that codes for a protein, wherein the protein is an anthocyanin 5-O-glucosyltransferase, which is an enzyme that transfers a glycoside to the 5 position of a flavonoid. The disclosed anthocyanin 5-O-glucosyltransferases were isolated from Perilla fruescens, Verbena hybrida, Torenia hybrida, and Petunia hybrida. Also disclosed are genes that code for a protein having a modified amino acid sequence relative to the above amino acid sequence and having activity that transfers a glycoside to the 5 position of a flavonoid, and a process for producing the above protein using said gene. This gene can be used to artificially alter the color of plants.Type: GrantFiled: February 10, 2005Date of Patent: March 10, 2009Assignee: International Flower Development Proprietary LimitedInventors: Masako Mizutani, Yoshikazu Tanaka, Takaaki Kusumi, Kazuki Saito, Mami Yamazaki, Gong Zhizhong
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Publication number: 20050257291Abstract: The present invention provides a gene that codes for a protein having an amino acid sequence described in any of SEQ ID NOs: 7 through 10 or 12 and having activity that transfers a glycoside to the 5 position of a flavonoid, a gene that codes for a protein having a modified amino acid sequence relative to the above amino acid sequence and having activity that transfers a glycoside to the 5 position of a flavonoid, and a process for producing the above protein using said gene. This gene can be used to artificially alter the color of plants.Type: ApplicationFiled: February 10, 2005Publication date: November 17, 2005Applicant: Suntory LimitedInventors: Masako Mizutani, Yoshikazu Tanaka, Takaaki Kusumi, Kazuki Saito, Mami Yamazaki, Gong Zhizhong
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Patent number: 6855862Abstract: The present invention provides DNA sequences isolated from Perilla, Torenia, Verbena and Petunia, encoding a protein having activity that transfers a glycoside to the 5 position of a flavonoid (5GT), a host cell and plants transformed with said DNA sequences and a process for producing a protein using said DNA sequences.Type: GrantFiled: July 16, 1998Date of Patent: February 15, 2005Assignee: Suntory LimitedInventors: Masako Mizutani, Yoshikazu Tanaka, Takaaki Kusumi, Kazuki Saito, Mami Yamazaki, Gong Zhizhong