Abstract: Bias supplies and plasma processing systems are disclosed. One bias supply comprises an output node, a return node, and a power section coupled to the output node and the return node. A resonant switch section is coupled to the power section at a first node, a second node, and a third node wherein the resonant switch section is configured to connect and disconnect a current pathway between the first node and the second node to apply an asymmetric periodic voltage waveform at the output node relative to the return node. The asymmetric periodic voltage waveform includes a first portion that begins with a first negative voltage and changes to a positive peak voltage, a second portion that changes from the positive peak voltage level to a third voltage level and a fourth portion that includes a negative voltage ramp from the third voltage level to a fourth voltage level.

Abstract: Computer vision systems and methods for automatic parcel alignment are provided. The system receives a geotagged aerial image, parcel information, and semantic information where each of the parcel and semantic information are overlaid on the geotagged aerial image. The system cleans the parcel information and the semantic information. The system optimizes the parcel information by grouping geo-registered parcels present in the geotagged aerial image into a plurality of islands and generating a plurality of parcel alignment solutions for each island of the plurality of islands. The system refines the plurality of parcel alignment solutions for each island and regularizes each island. The system generates a composite parcel alignment solution based on the refined plurality of parcel alignment solutions for each regularized island to align the geo-registered parcels of each regularized island with the geotagged aerial image.

Abstract: Computer vision systems and methods for noisy contour alignment are provided. The system generates a loss function and trains a convolutional neural network with the loss function and a plurality of images of a dataset to learn to align contours with progressively increasing complex forward and backward transforms over increasing scales. The system can align an attribute of an image of the dataset by the trained neural network.

Abstract: Computer vision systems and methods for text classification are provided. The system detects a plurality of text regions in an image and generates a bounding box for each detected text region. The system utilizes a neural network to recognize text present within each bounding box and classifies the recognized text, based on at least one extracted feature of each bounding box and the recognized text present within each bounding box, according to a plurality of predefined tags. The system can associate a key with a value and return a key-value pair for each predefined tag.

Abstract: Computer vision systems and methods for automatic parcel alignment are provided. The system receives a geotagged aerial image, parcel information, and semantic information where each of the parcel and semantic information are overlaid on the geotagged aerial image. The system cleans the parcel information and the semantic information. The system optimizes the parcel information by grouping geo-registered parcels present in the geotagged aerial image into a plurality of islands and generating a plurality of parcel alignment solutions for each island of the plurality of islands. The system refines the plurality of parcel alignment solutions for each island and regularizes each island. The system generates a composite parcel alignment solution based on the refined plurality of parcel alignment solutions for each regularized island to align the geo-registered parcels of each regularized island with the geotagged aerial image.

Abstract: The present invention relates to an improved process for the preparation of a compound of Formula (1), The invention also provides improved processes for the preparation of intermediates used in the synthesis of Formula (1). The compound of Formula (1) is used in the synthesis of Semaglutide.

Abstract: Bias supplies and plasma processing systems are disclosed. One bias supply comprises an output node, a return node, and a power section coupled to the output node and the return node. A resonant switch section is coupled to the power section at a first node, a second node, and a third node wherein the resonant switch section is configured to connect and disconnect a current pathway between the first node and the second node to apply an asymmetric periodic voltage waveform at the output node relative to the return node. The asymmetric periodic voltage waveform includes a first portion that begins with a first negative voltage and changes to a positive peak voltage, a second portion that changes from the positive peak voltage level to a third voltage level and a fourth portion that includes a negative voltage ramp from the third voltage level to a fourth voltage level.

Abstract: Bias supplies and plasma processing systems are disclosed. One bias supply comprises an output node, a return node, and a switch network and at least one power supply coupled to the output node and the return node. The switch network and the at least one power supply configured, in combination, to apply an asymmetric periodic voltage waveform and provide a corresponding current waveform at the output node relative to the return node. A timing parameter estimator receives a digital representation of a full cycle of the voltage and current waveforms, and generates a pulse width control signal based on a crossing time that the current waveform crosses a threshold current value after falling from a positive peak current value to control the switch network.

Abstract: A packaged oral care implement that includes a package and at least one oral care implement. The package may include a blister package having a receiving cavity and a flat panel coupled to the blister package to close an open end of the receiving cavity. The flat panel may include a first window aperture. A transparent film may be placed onto a front surface of the flat panel to cover or otherwise close the first window aperture.

Abstract: Systems and methods for detection and localization of image and document forgery. The method can include the step of receiving a dataset having a plurality of authentic images and a plurality of manipulated images. The method can also include the step of benchmarking a plurality of image forgery algorithms using the dataset. The method can further include the step of generating a plurality of receiver operating characteristic (ROC) curves for each of the plurality of image forgery algorithms. The method also includes the step of calculating a plurality of area under curve metrics for each of the plurality of ROC curves. The method further includes the step of training a neural network for image forgery based on the plurality of area under curve metrics.

Abstract: The present invention relates to an improved process for the preparation of a compound of formula (I), wherein PG1 may be independently selected from tert-butyloxycarbonyl (Boc), phthaloyl, 9-fluorenylmethyloxycarbonyl (Fmoc), triphenylmethyl (Trityl), carboxybenzyl (Cbz), trifluoroacetyl, benzyl (Bn), benzylidene, methanesulfonyl (Mesyl), toluene sulfonyl (Tosyl) or acyl; its isolation as solid and use for the preparation of the compound of formula (IV), in particular the compound of formula (IV) i.e. [(1R)-3-methyl-1[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid with more than 99.95% chiral purity, as measured by HPLC.

Abstract: A system for improved localization of image forgery. The system generates a variational information bottleneck objective function and works with input image patches to implement an encoder-decoder architecture. The encoder-decoder architecture controls an information flow between the input image patches and a representation layer. The system utilizes information bottleneck to learn useful residual noise patterns and ignore semantic content present in each input image patch. The system trains a neural network to learn a representation indicative of a statistical fingerprint of a source camera model from each input image patch while excluding semantic content thereof. The system can determine a splicing manipulation localization by the trained neural network.

Abstract: Computer vision systems and methods for optimizing correlation clustering for image segmentation are provided. The system receives input data and generates a correlation clustering formulation for Benders Decomposition for optimized correlation clustering of the input data. The system optimizes the Benders Decomposition for the generated correlation clustering formulation and performs image segmentation using the optimized Benders Decomposition.

Abstract: Computer vision systems and methods for noisy contour alignment are provided. The system generates a loss function and trains a convolutional neural network with the loss function and a plurality of images of a dataset to learn to align contours with progressively increasing complex forward and backward transforms over increasing scales. The system can align an attribute of an image of the dataset by the trained neural network.

Abstract: Computer vision systems and methods for text classification are provided. The system detects a plurality of text regions in an image and generates a bounding box for each detected text region. The system utilizes a neural network to recognize text present within each bounding box and classifies the recognized text, based on at least one extracted feature of each bounding box and the recognized text present within each bounding box, according to a plurality of predefined tags. The system can associate a key with a value and return a key-value pair for each predefined tag.

Abstract: Computer vision systems and methods for localizing image forgery are provided. The system generates a constrained convolution via a plurality of learned rich filters. The system trains a convolutional neural network with the constrained convolution and a plurality of images of a dataset to learn a low level representation of each image among the plurality of images. The low level representation is indicative of a statistical signature of at least one source camera model of each image. The system can determine a splicing manipulation localization by the trained convolutional neural network.

Abstract: A method of identifying an optimum treatment for a patient suffering from coronary artery disease, comprising: (i) providing patient information selected from: (a) status in the patient of one or more coronary disease associated biomarkers; (b) one or more items of medical history information selected from prior condition history, intervention history and medication history; (c) one or more items of diagnostic history, if the patient has a diagnostic history; and (d) one or more items of demographic data; (ii) aggregating the patient information in: (a) a Bayesian network; (b) a machine learning and neural network; (c) a rule-based system; and (d) a regression-based system; (iii) deriving a predicted probabilistic adverse event outcome for each intervention comprising percutaneous coronary intervention by placement of a bare metal stent, or a drug-coated stent; or by coronary artery bypass grafting; and (iv) determining the intervention having the lowest predicted probabilistic adverse outcome.

Abstract: The invention relates to a process for the preparation of ribociclib of formula V or its salts. The invention provides novel crystalline forms of ribociclib succinate and ribociclib trifluoroacetate. The present invention also relates to pharmaceutical compositions comprising a crystalline form of ribociclib succinate and at least a pharmaceutically acceptable carrier. It further relates to the use of such compositions in the treatment of cancer.

Abstract: Systems and methods for detection and localization of image and document forgery. The method can include the step of receiving a dataset having a plurality of authentic images and a plurality of manipulated images. The method can also include the step of benchmarking a plurality of image forgery algorithms using the dataset. The method can further include the step of generating a plurality of receiver operating characteristic (ROC) curves for each of the plurality of image forgery algorithms. The method also includes the step of calculating a plurality of area under curve metrics for each of the plurality of ROC curves. The method further includes the step of training a neural network for image forgery based on the plurality of area under curve metrics.

Abstract: Computer vision systems and methods for localizing image forgery are provided. The system generates a constrained convolution via a plurality of learned rich filters. The system trains a convolutional neural network with the constrained convolution and a plurality of images of a dataset to learn a low level representation of each image among the plurality of images. The low level representation is indicative of a statistical signature of at least one source camera model of each image. The system can determine a splicing manipulation localization by the trained convolutional neural network.