Patents by Inventor Manish Giri

Manish Giri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10399079
    Abstract: A microfluidic diagnostic device may comprise a fluid inlet to receive a fluid from a fluidic slot, a main microfluidic channel fluidly coupled to the fluid inlet, and a main microfluidic pump interposed between the fluid inlet and the main microfluidic channel to continuously circulate a fluid through the fluidic slot, fluid inlet, and main microfluidic channel wherein the width of the fluid inlet is different from the width of the main microfluidic channel. A diagnostic device, comprising a fluidic slot, a fluid inlet fluidly coupled to the fluidic slot, a main channel fluidly coupled to the fluid inlet, and an inlet pump interposed between the fluid inlet and channel wherein the cross-sectional area of the fluid inlet is relatively larger at least one point than the cross-sectional area of the channel.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: September 3, 2019
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Nicholas McGuinness, Chantelle Domingue, Manish Giri, Jeremy Sells
  • Patent number: 10365226
    Abstract: Provided in one example is an apparatus, including a substrate supporting a microfluidic channel, a bubble jet inertial pump supported by the substrate adjacent the microfluidic channel to pump fluid through the microfluidic channel and an optical sensor on a first side of the microfluidic channel. A light emitter on a second side of the microfluidic channel is to pass light across the microfluidic channel to the optical sensor.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: July 30, 2019
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Alexander Govyadinov, Charles M. Santori, Anita Rogacs, Diane R. Hammerstad, Manish Giri
  • Publication number: 20190210025
    Abstract: According to an example, a microfluidic apparatus may include a fluid slot and a foyer that is in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer. The microfluidic apparatus may also include an electrical sensor to measure a change in an electrical field caused by a particle of interest in a fluid passing through the channel from the fluid slot to the foyer, an actuator to apply pressure onto fluid contained in the foyer, and a controller to receive the measured change in the electrical field from the electrical sensor, determine, from the received change in the electrical field, an electrical signature of the particle of interest, and control the actuator to control movement of the particle of interest based upon the determined electrical signature of the particle of interest.
    Type: Application
    Filed: July 26, 2016
    Publication date: July 11, 2019
    Inventors: Chantelle DOMINGUE, Tod WOODFORD, Manish GIRI, Matthew David SMITH, George H CORRIGAN III, Masoud ZAVAREHI, Joshua M. YU
  • Publication number: 20190151848
    Abstract: According to an example, a microfluidic apparatus may include a fluid slot, a foyer in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer, a sensor to detect a presence of a particle of interest in a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to receive information from the sensor, determine, from the received information, whether a particle of interest has passed through the channel, and control the actuator to expel fluid in the foyer through the nozzle based upon the determination.
    Type: Application
    Filed: July 26, 2016
    Publication date: May 23, 2019
    Inventors: Jeffrey A NIELSEN, Manish GIRI, Chantelle DOMINGUE, Kenneth WARD, Christie DUDENHOEFER, Matthew David SMITH, Joshua M. YU, Hilary ELY
  • Publication number: 20190151849
    Abstract: According to an example, a microfluidic apparatus may include a channel, a foyer, in which the foyer is in fluid communication with the channel and in which the channel has a smaller width than the foyer, a sensor to sense a property of a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to determine whether the sensed property of the fluid meets a predetermined condition and to perform a predefined action in response to the sensed property of the fluid meeting the predetermined condition.
    Type: Application
    Filed: July 26, 2016
    Publication date: May 23, 2019
    Inventors: Jeffrey A NIELSEN, Manish GIRI, Chantelle DOMINGUE, Kenneth WARD, Christie DUDENHOEFER, Matthew David SMITH, Joshua M. YU, Diane R. HAMMERSTAD, Hilary ELY
  • Publication number: 20190127219
    Abstract: Example sensor apparatus for microfluidic devices and related methods are disclosed. In examples disclosed herein, a method of fabricating a sensor apparatus for a microfluidic device includes etching a portion of an intermediate layer to form a sensor chamber in a substrate assembly, where the substrate assembly has a base layer and the intermediate layer, and where the base layer comprises a first material and the intermediate layer comprises a second material different than the first material. The method includes forming a first electrode and a second electrode in the sensor chamber. The method also includes forming a fluidic transport channel in fluid communication with the sensor chamber, where the fluidic transport channel comprises a third material different than the first material and the second material.
    Type: Application
    Filed: July 22, 2016
    Publication date: May 2, 2019
    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
    Inventors: Sadiq Bengali, Manish Giri
  • Patent number: 10272428
    Abstract: A microfluidic device can include: a channel; a fluid inlet to pass fluid into the channel from a reservoir; a sensor disposed in the channel; and a pump actuator disposed in the channel apart from the sensor to induce fluid flow into the channel.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: April 30, 2019
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Nicholas M. McGuinness, Manish Giri, Melinda M. Valencia, Chantelle Domingue, Andrew L. Van Brocklin, Dustin W. Blair
  • Patent number: 10241066
    Abstract: A microfluidic sensing device comprises a channel and an impedance sensor within the channel. The impedance sensor comprises a local ground and an electrode within the channel. The local ground and the electrode are to form an electric field region that is elongated along the channel.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: March 26, 2019
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Nicholas Matthew Cooper McGuinness, Melinda M. Valencia, Manish Giri, Chantelle Elizabeth Domingue, Jeremy Sells, Matthew David Smith
  • Publication number: 20190039063
    Abstract: An apparatus includes a chamber, a nozzle connected to the chamber, a fluid driver proximate the driver to expel fluid from the chamber through the nozzle, a microfluidic passage, an inlet connecting the microfluidic passage and the chamber, a sensor proximate the inlet to sense fluid within a fluid sensing zone within the inlet, and a particle aggregation limiter to control aggregation of particles within the sensing zone.
    Type: Application
    Filed: January 22, 2016
    Publication date: February 7, 2019
    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
    Inventors: Chantelle E. Domingue, Manish Giri
  • Publication number: 20180356327
    Abstract: Examples herein provide a device. The device includes a sample delivery component, which includes: a reagent chamber to contain at least one reagent; a sample chamber to contain a fluid sample; and a delivery channel extending from the reagent chamber and in fluid communication with the sample chamber and an output port, wherein the delivery channel is conducive to mixing the at least one reagent and the fluid sample to form a mixture before the mixture reaches the output port and be discharged therefrom. The device includes a testing cassette detachable from the delivery component, which includes: an input port in fluid communication with a microfluidic reservoir, the input port to receive the discharged fluid sample from the output port; and a micro-fabricated integrated sensor in a microfluidic channel extending from the microfluidic reservoir.
    Type: Application
    Filed: November 24, 2015
    Publication date: December 13, 2018
    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
    Inventors: Robert MOLINE, Manish GIRI, Chantelle DOMINGUE
  • Publication number: 20180321263
    Abstract: Examples herein provide a device. The device includes a testing cassette including: a microfluidic channel connecting an input port at a first end to at least one sensor area at a second end, the channel is to allow a blood sample to flow from the input port to the at least one sensor area; at least two electrodes; and a micro-fabricated integrated sensor, wherein when an electrical potential difference is applied over the blood sample, the sensor is to measure, over a duration of time, an electrical signal passing through the blood sample as the blood sample flows from the input port to the at least one sensor area and begin to coagulate, thereby obtaining a measurement function as a function of time. The device includes a processor to correlate the measurement function to a characteristic of the blood sample.
    Type: Application
    Filed: March 7, 2016
    Publication date: November 8, 2018
    Inventors: Rachel M. White, Manish Giri, Chantelle Domingue, Joshua M. Yu, Matthew David Smith, Sait M A Shameed
  • Publication number: 20180285153
    Abstract: A system and method for managing a microfluidics device. The system includes a microfluidics device; a controller with a first processor which receives outputs from the microfluidics device and provides inputs to the microfluidics device; and a computing device with a second processor and an application program interface (API). The computing device provides instructions to the controller using the API. The instructions are executed by the first processor to produce real-time outputs to the microfluidics device.
    Type: Application
    Filed: February 4, 2016
    Publication date: October 4, 2018
    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
    Inventors: Joshua M. Yu, Matthew David Smith, Manish Giri, Shameed Salt M A
  • Publication number: 20180264470
    Abstract: A controller is connected to controlled devices on a microfluidic chip with a multiplexer. Signal transmission band width is differently allocated amongst the plurality of controlled devices on the microfluidic chip.
    Type: Application
    Filed: January 30, 2015
    Publication date: September 20, 2018
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Sirena Lu, Manish Giri, Matthew David Smith, Melinda M. Valencia
  • Publication number: 20180236765
    Abstract: A device including a substrate and a channel formed in a layer disposed on the substrate. The layer includes a cavitation layer and a passivation layer to mitigate the effects of hydrodynamic cavitation on a surface of the channel. The passivation and cavitation material and thickness are optimized thermally to nucleate and eject a bubble at low voltages. A resistive heating element is disposed within the channel that is activated to create a micro-fluidic pump to advance a fluid through the channel. A sensor is disposed within the channel to measure a characteristic of the fluid passing through the channel.
    Type: Application
    Filed: January 25, 2016
    Publication date: August 23, 2018
    Inventors: Manish Giri, Sadiq Bengali
  • Publication number: 20180229236
    Abstract: A microfluidic diagnostic chip may, in an example, include a number of microfluidic channels defined in a substrate each microfluidic channel fluidly coupled to at least one fluidic slot; the at least one fluidic slot to receive a number of fluids, and a number of gold sensors each gold sensor having a thickness of between 1500 and 5000 angstroms (?).
    Type: Application
    Filed: January 29, 2016
    Publication date: August 16, 2018
    Inventors: Sadiq Bengali, Manish Giri
  • Publication number: 20180221870
    Abstract: An apparatus includes a microfluidic passage, a chamber, an inlet connecting the microfluidic passage to the chamber, a sensor proximate the inlet to sense fluid within the inlet, a first nozzle, a first fluid driver to move fluid through the first nozzle to draw fluid across the inlet, a second nozzle, a second fluid driver to move fluid through the second nozzle to draw fluid across the inlet and a controller. The controller sequentially actuates the first fluid driver and the second fluid driver.
    Type: Application
    Filed: January 22, 2016
    Publication date: August 9, 2018
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Chantelle E. DOMINGUE, Manish GIRI, Matthew David SMITH, Joshua M. YU, Jeremy SELLS, George H. CORRIGAN
  • Publication number: 20180224425
    Abstract: Examples herein provide a method. The method includes applying an electrical potential difference over a blood sample in a testing cassette of a microfluidic device, the cassette including a microfluidic channel through which the blood sample flows. The method includes measuring, over a duration of time, an electrical signal passing through the blood sample as the blood sample flows from a first end and coagulates at a second end of the microfluidic channel to obtain a measurement function as a function of time. The method also includes correlating the measurement function to a characteristic of the blood sample.
    Type: Application
    Filed: March 7, 2016
    Publication date: August 9, 2018
    Inventors: Shameed SAIT M A, Rachel M. WHITE, Chantelle DOMINGUE, Manish GIRI
  • Publication number: 20180214867
    Abstract: Provided herein are a system and method for using a microfluidics device. The system includes: a plurality of pumps and a plurality of sensors; a first communication line to select a pump from the plurality of pumps and select a sensor from the plurality of sensors; a second communication line selectively connected to the selected pump; and a third communication line selectively connected to the selected sensor.
    Type: Application
    Filed: January 29, 2016
    Publication date: August 2, 2018
    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
    Inventors: Matthew David Smith, Manish Giri, Chantelle Domingue
  • Publication number: 20180043687
    Abstract: Provided in one example is an apparatus, including a substrate supporting a microfluidic channel, a bubble jet inertial pump supported by the substrate adjacent the microfluidic channel to pump fluid through the microfluidic channel and an optical sensor on a first side of the microfluidic channel. A light emitter on a second side of the microfluidic channel is to pass light across the microfluidic channel to the optical sensor.
    Type: Application
    Filed: April 30, 2015
    Publication date: February 15, 2018
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Alexander Govyadinov, Charles M. Santori, Anita Rogacs, Diane R. Hammerstad, Manish Giri
  • Publication number: 20180043356
    Abstract: A device includes a microfluidic channel structure on a substrate and a first resistive structure on the substrate to control the temperature of at least the substrate. The first resistive structure is separate from, and independent of the, microfluidic channel structure. In some instances, the device includes a second resistive structure.
    Type: Application
    Filed: January 30, 2015
    Publication date: February 15, 2018
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Chantelle Domingue, Manish Giri, Sadiq Bengali