Patents by Inventor Manjinder Singh Phull

Manjinder Singh Phull has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RIFAXIMIN
    Publication number: 20230116935
    Abstract: Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to crystalline rifaximin and vice versa.
    Type: Application
    Filed: May 17, 2022
    Publication date: April 20, 2023
    Applicant: CIPLA Limited
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Manjinder Singh Phull, Maruti Ghagare
  • Salts of antiviral phosphonate analogues and process for preparation thereof
    Patent number: 11390637
    Abstract: The present invention relates to certain acid salts of (((1-(6-amino-9H-purin-9-yl)propan-2-yloxy)methyl)(phenoxy) phosphoryloxy)methyl pivalate of Formula (I), to processes for their preparation; to pharmaceutical compositions comprising such compounds, and methods of treating a disease which responds to inhibition of nucleotide reverse transcriptase activity.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: July 19, 2022
    Assignee: Cipla Limited
    Inventors: Manjinder Singh Phull, Ashwini Amol Sawant, Dharmaraj Ramachandra Rao, Geena Malhotra, Manish Gopaldas Gangrade
  • NOVEL POLYMORPHS OF INTEGRASE INHIBITOR
    Publication number: 20220144851
    Abstract: Novel crystalline forms of Bictegravir sodium, pharmaceutical compositions containing said crystalline forms and the use of said crystalline forms in the treatment of HIV infection are disclosed. The present invention is further directed to the processes for the preparation of the novel crystalline forms.
    Type: Application
    Filed: February 6, 2020
    Publication date: May 12, 2022
    Inventors: Venkata Srinivas PULLELA, Srinivas Laxminarayan PATHI, Ramanaiah CHENNURU, Manjinder Singh PHULL, Anjaneyaraju INDUKARI
  • Process for the preparation of piperine
    Patent number: 11267798
    Abstract: The present application relates to a process for the preparation of piperine of high purity having low concentrations of isomeric impurities.
    Type: Grant
    Filed: October 13, 2018
    Date of Patent: March 8, 2022
    Assignee: CIPLA LIMITED
    Inventors: Manjinder Singh Phull, Dharmaraj Ramachandra Rao, Geena Malhortra, Dilip Ramdas Birari, Sachin Vasant Desai
  • PROCESS FOR THE PREPARATION OF PIPERINE
    Publication number: 20210363126
    Abstract: The present application relates to a process for the preparation of piperine of high purity having low concentrations of isomeric impurities.
    Type: Application
    Filed: October 13, 2018
    Publication date: November 25, 2021
    Inventors: Manjinder Singh PHULL, Dharmaraj Ramachandra RAO, Geena MALHORTRA, Dilip Ramdas BIRARI, Sachin Vasant DESAI
  • New Polymorphs of Dolutegravir Sodium
    Publication number: 20210040116
    Abstract: The present invention relates to new polymorphs of dolutegravir sodium and processes for the preparation of the new polymorphs of dolutegravir sodium. The present invention also provides pharmaceutical compositions comprising these new polymorphs, and medical uses of the polymorphs.
    Type: Application
    Filed: September 7, 2017
    Publication date: February 11, 2021
    Inventors: Dharmaraj Ramachandra RAO, Geena MALHOTRA, Manjinder Singh PHULL, Ashwini Amol SAWANT, Amit NAIK, Manish Gopaldas GANGRADE, Shashirekha KANATHALA
  • POLYMORPHIC FORMS OF (9-[(R)-2-[[(S)-[[(S)-1-(ISOPROPOXYCARBONYL)ETHYL]AMINO]PHENOXY PHOSPHINYL]METHOXY]PROPYL] ADENINE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
    Publication number: 20200407382
    Abstract: The present invention discloses novel crystalline polymorphic forms of (9-[(R)-2-[[(S)-[[(S)-1-(isopropoxy carbonyl) ethyl] amino] phenoxyphosphinyl] methoxy]propyl] adenine hemifumarate and 9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl] amino]phenoxy phosphinyl]methoxy]propyl] adenine monofumarate, methods of preparation, pharmaceutical compositions and methods of therapeutic treatment involving polymorphic forms thereof.
    Type: Application
    Filed: December 28, 2018
    Publication date: December 31, 2020
    Inventors: Dharmaraj Ramachandra RAO, Geena MALHOTRA, Srinivas Laxminarayan PATHI, Manjinder Singh PHULL, Ramanaiah CHENNURU
  • RIFAXIMIN
    Publication number: 20200368212
    Abstract: Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to crystalline rifaximin and vice versa.
    Type: Application
    Filed: February 28, 2020
    Publication date: November 26, 2020
    Applicant: CIPLA Limited
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Manjinder Singh Phull, Muruti Ghagare
  • Rifaximin
    Patent number: 10702505
    Abstract: Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to crystalline rifaximin and vice versa.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: July 7, 2020
    Assignee: CIPLA Limited
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Manjinder Singh Phull, Muruti Ghagare
  • Salts of Antiviral Phosphonate Analogues and Process for Preparation Thereof
    Publication number: 20200131211
    Abstract: The present invention relates to certain acid salts of (((1-(6-amino-9H-purin-9-yl)propan-2-yloxy)methyl)(phenoxy) phosphoryloxy)methyl pivalate of Formula (I), to processes for their preparation; to pharmaceutical compositions comprising such compounds, and methods of treating a disease which responds to inhibition of nucleotide reverse transcriptase activity.
    Type: Application
    Filed: March 16, 2018
    Publication date: April 30, 2020
    Inventors: Manjinder Singh PHULL, Ashwini Amol SAWANT, Dharmaraj Ramachandra RAO, Geena MALHOTRA, Manish Gopaldas GANGRADE
  • Polymorphic forms of methyl((1S)-1-(((2S)-2-(5-(4?-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate and salts thereof
    Patent number: 10300044
    Abstract: Amorphous methyl((1S)-1-(((2S)-2-(5-(4?-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl) carbonyl)-2-methylpropyl) carbamate free base, amorphous methyl((1S)-1-(((2S)-2-(5-(4?-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl) carbonyl)-2-methylpropyl) carbamate dihydrochloride, methods of making them, and pharmaceutical compositions containing them.
    Type: Grant
    Filed: December 24, 2015
    Date of Patent: May 28, 2019
    Assignee: Cipla Limited
    Inventors: Dharmaraj Ramachandra Rao, Geena Malhotra, Manjinder Singh Phull, Shashirekha Kanathala, Manish Gopaldas Gangrade
  • RIFAXIMIN
    Publication number: 20180235944
    Abstract: Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to crystalline rifaximin and vice versa.
    Type: Application
    Filed: January 17, 2018
    Publication date: August 23, 2018
    Applicant: CIPLA Limited
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Manjinder Singh Phull, Muruti Ghagare
  • Rifaximin
    Patent number: 9877953
    Abstract: Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to crystalline rifaximin and vice versa.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: January 30, 2018
    Assignee: CIPLA LIMITED
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Manjinder Singh Phull, Maruti Ghagare
  • Polymorphic Forms of Methyl((1S)-1-(((2S)-2-(5-(4'-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl) carbonyl)-2-methylpropyl)carbamate and Salts Thereof
    Publication number: 20170354644
    Abstract: Amorphous methyl((1S)-1-(((2S)-2-(5-(4?-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl) carbonyl)-2-methylpropyl) carbamate free base, amorphous methyl((1S)-1-(((2S)-2-(5-(4?-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2-yl)-1-pyrrolidinyl) carbonyl)-2-methylpropyl) carbamate dihydrochloride, methods of making them, and pharmaceutical compositions containing them.
    Type: Application
    Filed: December 24, 2015
    Publication date: December 14, 2017
    Inventors: Dharmaraj Ramachandra RAO, Geena MALHOTRA, Manjinder Singh PHULL, Shashirekha KANATHALA, Manish Gopaldas GANGRADE
  • RIFAXIMIN
    Publication number: 20160374999
    Abstract: Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to crystalline rifaximin and vice versa.
    Type: Application
    Filed: July 29, 2016
    Publication date: December 29, 2016
    Applicant: CIPLA Limited
    Inventors: Dharmaraj R. Rao, Rajendra Narayanrao Kankan, Manjinder Singh Phull, Maruti Ghagare
  • Rifaximin
    Patent number: 9403844
    Abstract: Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to crystalline rifaximin and vice versa.
    Type: Grant
    Filed: June 8, 2015
    Date of Patent: August 2, 2016
    Assignee: Cipla Ltd.
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Manjinder Singh Phull, Maruti Ghagare
  • Antiviral phosphonate analogues and process for preparation thereof
    Patent number: 9227990
    Abstract: The present invention provides a compound of the Formula (I) wherein R is 9-isopropyl-9H-purin-6-amine; 2-amino-9-isopropyl-1H-purin-6(9H)-one; 4-amino-1-isopropyl pyrimidin-2(1H)-one; or 1-isopropyl-5-methylpyrimidine-2,4(1H,3H)-dione, R? is —CH2OC(O)R?, and R? is —C(CH3)3 or —CH(CH3)2 including pharmaceutically acceptable salts thereof. The present invention also provides a process for preparing a compound of formula (Ia) and a compound of formula (I) for use in treating a viral infection.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: January 5, 2016
    Assignee: CIPLA LIMITED
    Inventors: Manjinder Singh Phull, Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao
  • Antiviral Phosphonate Analogues and Process for Preparation Thereof
    Publication number: 20150291639
    Abstract: The present invention provides a compound of the Formula (I) wherein R is 9-isopropyl-9H-purin-6-amine; 2-amino-9-isopropyl-1H-purin-6(9H)-one; 4-amino-1-isopropyl pyrimidin-2(1H)-one; or 1-isopropyl-5-methylpyrimidine-2,4(1H,3H)-dione, R? is —CH2OC(O)R?, and R? is —C(CH3)3 or —CH(CH3)2 including pharmaceutically acceptable salts thereof. The present invention also provides a process for preparing a compound of formula (Ia) and a compound of formula (I) for use in treating a viral infection.
    Type: Application
    Filed: October 29, 2013
    Publication date: October 15, 2015
    Applicant: Cipla Limited
    Inventors: Manjinder Singh Phull, Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao
  • Rifaximin
    Publication number: 20150266898
    Abstract: Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to crystalline rifaximin and vice versa.
    Type: Application
    Filed: June 8, 2015
    Publication date: September 24, 2015
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Manjinder Singh Phull
  • Darunavir Polymorph and Process for Preparation Thereof
    Publication number: 20150141383
    Abstract: There is disclosed crystalline darunavir hydrate substantially free of any non-aqueous solvent.
    Type: Application
    Filed: January 30, 2015
    Publication date: May 21, 2015
    Inventors: Manjinder Singh PHULL, Dharmaraj Ramachandra RAO, Rajendra Narayanrao KANKAN