Abstract: The present invention discloses stable, solid oral pharmaceutical composition comprising Lanthanum carbonate having more than 6 molecules of water per molecule of lanthanum carbonate and pharmaceutically acceptable carriers or diluents, wherein said carrier or diluent excludes monosaccharide/s or disaccharide/s, such that the composition has comparable in-vitro dissolution profile similar to that of FOSRENOL®. Also disclosed is a wet granulation process for making the same.

Abstract: The present invention discloses stable, solid oral pharmaceutical composition comprising Lanthanum carbonate having more than 6 molecules of water per molecule of lanthanum carbonate and pharmaceutically acceptable carriers or diluents, wherein said carrier or diluent excludes monosaccharide/s or disaccharide/s, such that the composition has comparable in-vitro dissolution profile similar to that of FOSRENOL®. Also disclosed is a wet granulation process for making the same.

Abstract: Disclosed herein are methods for detecting a water leak in a locomotive engine cooling system comprising numerous components, each being a potential source of leakage of water. The method typically comprises performing at least one inspection providing an indication of a water leak from an engine cooling system of the locomotive. The step of performing at least one inspection may comprise at least one of several steps including performing a visual inspection to determine if water is leaking from a portion of the cooling system external to the engine; performing a visual inspection of exhaust of the engine to detect an indication of water vapor in the exhaust; performing a visual inspection to detect an indication of water leaking into an intake air manifold 30 of the engine; performing an engine oil analysis to detect water in the engine lubricant; reviewing a fault log history for the locomotive; and checking a level of a cooling system sight glass.

Abstract: A system and method for monitoring the effectiveness of a heat exchange unit, which comprises at least one or more sensors for taking a plurality of temperature readings of a heated fluid, a coolant and fluids passing through the heat exchange unit. The temperature readings are transmitted and/or entered into a processor capable of comparing the temperature readings and calculating a measure of effectiveness of the heat exchange unit. The processor is in communication with a database that maintains at least one predetermined parameter limit associated with the effectiveness of the heat exchange unit. The processor analyzes the data and is also capable of generating a signal indicative of the health or condition of the heat exchange unit.

Abstract: A system and method for monitoring the effectiveness of a heat exchange unit, which comprises at least one or more sensors for taking a plurality of temperature readings of a heated fluid, a coolant and fluids passing through the heat exchange unit. The temperature readings are transmitted and/or entered into a processor capable of comparing the temperature readings and calculating a measure of effectiveness of the heat exchange unit. The processor is in communication with a database that maintains at least one predetermined parameter limit associated with the effectiveness of the heat exchange unit. The processor analyzes the data and is also capable of generating a signal indicative of the health or condition of the heat exchange unit.