Abstract: The disclosure herein describes enhancing data durability of a base component using a delta component. A delta component is generated based on the base component becoming unavailable. The delta component is configured to include unwritten storage space with an address space matching the base component and a tracking bitmap associated with data blocks of the address space of the delta component. Write operations targeted for the base component are routed to the delta component. Based on the routed write operations, bits associated with data blocks affected by the write operations are changed in the tracking bitmap. Based on the base component becoming available, data blocks affected by routed write operations are identified based on the tracking bitmap and the identified data blocks are synchronized from the delta component to the base component. The delta component is then removed.

Abstract: An example virtualized computing system includes a cluster of hosts having a virtualization layer executing thereon and configured to manage virtual machines (VMs); first and second local storage devices in a first host, the first local storage device being part of a virtual storage area network (vSAN) and the second local storage device being exclusive of the vSAN; and an orchestration control plane, integrated with the virtualization layer and including a master server managing state of the orchestration control plane, the state including objects representing the hosts and the VMs, the orchestration control plane deploying a persistent application executing on a first VM, the persistent application storing persistent data on the second local storage device; and a virtualization management server configured to manage the cluster and to cooperate with the orchestration control plane to modify the state to notify the master server of a virtual infrastructure (VI) event.

Abstract: The disclosure provides an approach for fault tolerance handling. Embodiments include determining, by a management component, that a host stores data relating to a service. Embodiments include receiving, by the management component, fault tolerance information from the service, the fault tolerance information comprising first information about host failures tolerated by the service and second information about existing host failures related to the service. Embodiments include determining, by the management component, based on the fault tolerance information from the service, whether the service will tolerate the host becoming unavailable. Embodiments include performing, by the management component, one or more actions based on the determining of whether the service will tolerate the host becoming unavailable.

Abstract: Techniques are described for storing a virtual disk in an object store comprising a plurality of physical storage devices housed in a plurality of host computers. A profile is received for creation of the virtual disk wherein the profile specifies storage properties desired for an intended use of the virtual disk. A virtual disk blueprint is generated based on the profile such that that the virtual disk blueprint describes a storage organization for the virtual disk that addresses redundancy or performance requirements corresponding to the profile. A set of the physical storage devices that can store components of the virtual disk in a manner that satisfies the storage organization is then determined.

Abstract: Techniques for predicting the outcome of a storage management operation on a hyper-converged infrastructure (HCI) deployment are provided. In one set of embodiments, a computer system can retrieve a current storage resource state of the HCI deployment. The computer system can then execute a simulation of the storage management operation in view of the current storage resource state, where the executing includes performing one or more simulated data movements between one or more host systems in the HCI deployment. Upon completing the simulation, the computer system can generate a report including, among other things, a predicted result status of the storage management operation based on the simulation.

Abstract: An example virtualized computing system includes a cluster of hosts having a virtualization layer executing thereon and configured to manage virtual machines (VMs); a local storage device in a first host of the cluster, the local storage device configured as direct-attach storage; and an orchestration control plane, integrated with the virtualization layer, the orchestration control plane including a master server managing state of the orchestration control plane, the state including objects representing the hosts and the VMs, the orchestration control plane deploying a persistent application executing on a first VM of the VMs, the persistent application storing persistent data on the direct-attach storage.

Abstract: The disclosure provides an approach for fault tolerance handling. Embodiments include determining, by a management component, that a host stores data relating to a service. Embodiments include receiving, by the management component, fault tolerance information from the service, the fault tolerance information comprising first information about host failures tolerated by the service and second information about existing host failures related to the service. Embodiments include determining, by the management component, based on the fault tolerance information from the service, whether the service will tolerate the host becoming unavailable. Embodiments include performing, by the management component, one or more actions based on the determining of whether the service will tolerate the host becoming unavailable.

Abstract: An example virtualized computing system includes a cluster of hosts having a virtualization layer executing thereon and configured to manage virtual machines (VMs); a local storage device in a first host of the cluster, the local storage device configured as direct-attach storage; and an orchestration control plane, integrated with the virtualization layer, the orchestration control plane including a master server managing state of the orchestration control plane, the state including objects representing the hosts and the VMs, the orchestration control plane deploying a persistent application executing on a first VM of the VMs, the persistent application storing persistent data on the direct-attach storage.

Abstract: Embodiments presented herein techniques for balancing a multidimensional set of resources of different types within a distributed resources system. Each host computer providing the resources publishes a status on current resource usage by guest clients. Upon identifying a local imbalance, the host computer determines a source workload to migrate to or from the resources container to minimize the variance in resource usage. Additionally, when placing a new resource workload, the host computer selects a resources container that minimizes the variance to further balance resource usage.

Abstract: The disclosure herein describes mounting a shared data store, remote from a client cluster, as a remote data store on the client cluster. An abstraction interface of the remote data store on the client cluster is configured to receive data operations that are in a local data store-based format. A control path interface is established between the server cluster and the client cluster, and network location data associated with the shared data store is received by the client cluster via the established control path interface. Based on the network location data, a data path interface is established between the client cluster and the shared data store of the server cluster, whereby data operations directed to the abstraction interface of the remote data store on the client cluster are routed to the shared data store of the server cluster via the established data path interface.

Abstract: An example virtualized computing system includes a cluster of hosts having a virtualization layer executing thereon and configured to manage virtual machines (VMs); first and second local storage devices in a first host, the first local storage device being part of a virtual storage area network (vSAN) and the second local storage device being exclusive of the vSAN; and an orchestration control plane, integrated with the virtualization layer and including a master server managing state of the orchestration control plane, the state including objects representing the hosts and the VMs, the orchestration control plane deploying a persistent application executing on a first VM, the persistent application storing persistent data on the second local storage device; and a virtualization management server configured to manage the cluster and to cooperate with the orchestration control plane to modify the state to notify the master server of a virtual infrastructure (VI) event.

Abstract: Example methods are provided for unbalanced storage resource usage configuration for a distributed storage system in a virtualized computing environment. An example method may include obtaining usage data associated with multiple storage resources forming the distributed storage system. The multiple storage resources are supported by the multiple hosts. Based on the usage data, the method may further include determining a higher usage set and a lower usage set of one or more storage resources from the multiple storage resources and configuring the multiple hosts to use the multiple storage resources in an unbalanced manner by using the higher usage set of one or more storage resources at a higher usage level compared to the lower usage set of one or more storage resources.

Abstract: The disclosure herein describes mounting a shared data store, remote from a client cluster, as a remote data store on the client cluster. An abstraction interface of the remote data store on the client cluster is configured to receive data operations that are in a local data store-based format. A control path interface is established between the server cluster and the client cluster, and network location data associated with the shared data store is received by the client cluster via the established control path interface. Based on the network location data, a data path interface is established between the client cluster and the shared data store of the server cluster, whereby data operations directed to the abstraction interface of the remote data store on the client cluster are routed to the shared data store of the server cluster via the established data path interface.

Abstract: An example virtualized computing system includes a cluster of hosts having a virtualization layer executing thereon and configured to manage virtual machines (VMs); a local storage device in a first host of the cluster, the local storage device configured as direct-attach storage; and an orchestration control plane, integrated with the virtualization layer, the orchestration control plane including a master server managing state of the orchestration control plane, the state including objects representing the hosts and the VMs, the orchestration control plane deploying a persistent application executing on a first VM of the VMs, the persistent application storing persistent data on the direct-attach storage.

Abstract: Techniques are described for storing a virtual disk in an object store comprising a plurality of physical storage devices housed in a plurality of host computers. A profile is received for creation of the virtual disk wherein the profile specifies storage properties desired for an intended use of the virtual disk. A virtual disk blueprint is generated based on the profile such that that the virtual disk blueprint describes a storage organization for the virtual disk that addresses redundancy or performance requirements corresponding to the profile. A set of the physical storage devices that can store components of the virtual disk in a manner that satisfies the storage organization is then determined.

Abstract: Techniques are described for storing a virtual disk in an object store comprising a plurality of physical storage devices housed in a plurality of host computers. A profile is received for creation of the virtual disk wherein the profile specifies storage properties desired for an intended use of the virtual disk. A virtual disk blueprint is generated based on the profile such that that the virtual disk blueprint describes a storage organization for the virtual disk that addresses redundancy or performance requirements corresponding to the profile. A set of the physical storage devices that can store components of the virtual disk in a manner that satisfies the storage organization is then determined.

Abstract: Certain embodiments are directed to methods and compositions related to delivery of therapeutic agents via syncytiotrophoblast-derived extracellular vesicles (EVs).

Abstract: The disclosure herein describes enhancing data durability of a base component using a delta component. A delta component is generated based on the base component becoming unavailable. The delta component is configured to include unwritten storage space with an address space matching the base component and a tracking bitmap associated with data blocks of the address space of the delta component. Write operations targeted for the base component are routed to the delta component. Based on the routed write operations, bits associated with data blocks affected by the write operations are changed in the tracking bitmap. Based on the base component becoming available, data blocks affected by routed write operations are identified based on the tracking bitmap and the identified data blocks are synchronized from the delta component to the base component. The delta component is then removed.

Abstract: Embodiments presented herein techniques for balancing a multidimensional set of resources of different types within a distributed resources system. Each host computer providing the resources publishes a status on current resource usage by guest clients. Upon identifying a local imbalance, the host computer determines a source workload to migrate to or from the resources container to minimize the variance in resource usage. Additionally, when placing a new resource workload, the host computer selects a resources container that minimizes the variance to further balance resource usage.

Abstract: The disclosure herein describes mounting a shared data store, remote from a client cluster, as a remote data store on the client cluster. An abstraction interface of the remote data store on the client cluster is configured to receive data operations that are in a local data store-based format. A control path interface is established between the server cluster and the client cluster, and network location data associated with the shared data store is received by the client cluster via the established control path interface. Based on the network location data, a data path interface is established between the client cluster and the shared data store of the server cluster, whereby data operations directed to the abstraction interface of the remote data store on the client cluster are routed to the shared data store of the server cluster via the established data path interface.