Patents by Inventor Manuel Aivado

Manuel Aivado has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
    Publication number: 20230106577
    Abstract: Methods for treating a solid tumor, determined to lack a p53 deactivation mutation, in a subject are provided. Also provided are peptidomimetic macrocycles for use in treatment of a solid tumor, determined to lack a p53 deactivation mutation, in a subject.
    Type: Application
    Filed: June 21, 2022
    Publication date: April 6, 2023
    Inventors: Hubert CHEN, David Allen ANNIS, Yong CHANG, Manuel AIVADO, Karen OLSON, Chris VIAU
  • Peptidomimetic macrocycles and uses thereof
    Patent number: 11091522
    Abstract: The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: August 17, 2021
    Assignee: Aileron Therapeutics, Inc.
    Inventors: Manuel Aivado, Vincent Guerlavais, Karen Olson, David Allen Annis
  • PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
    Publication number: 20200369728
    Abstract: Provided herein are peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease. Also provided here in are methods of using such macrocycles in combination with at least one additional pharmaceutically active agent for treatment of disorders, for example for treatment of cancer.
    Type: Application
    Filed: May 22, 2020
    Publication date: November 26, 2020
    Inventors: Manuel AIVADO, Vincent GUERLAVAIS, Karen OLSON
  • PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
    Publication number: 20200085908
    Abstract: Methods for treating solid tumor, determined to lack a p53 deactivation mutation, in a subject are provided. Also provided are peptidomimetic macrocycles for use in treatment of a solid tumor, determined to lack a p53 deactivation mutation, in a subject.
    Type: Application
    Filed: September 6, 2019
    Publication date: March 19, 2020
    Inventors: Hubert CHEN, David Allen ANNIS, Yong CHANG, Manuel AIVADO, Karen OLSON, Chris VIAU
  • PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
    Publication number: 20200040048
    Abstract: The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
    Type: Application
    Filed: July 23, 2019
    Publication date: February 6, 2020
    Inventors: Manuel AIVADO, Vincent GUERLAVAIS, Karen OLSON, David Allen ANNIS
  • Peptidomimetic macrocycles and uses thereof
    Patent number: 10471120
    Abstract: Methods for treating solid tumor, determined to lack a p53 deactivation mutation, in a subject are provided. Also provided are peptidomimetic macrocycles for use in treatment of a solid tumor, determined to lack a p53 deactivation mutation, in a subject.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: November 12, 2019
    Assignee: AILERON THERAPEUTICS, INC.
    Inventors: Hubert Chen, David Allen Annis, Yong Chang, Manuel Aivado, Karen Olson, Chris J. Viau
  • PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
    Publication number: 20190269753
    Abstract: Methods for treating solid tumor, determined to lack a p53 deactivation mutation, in a subject are provided. Also provided are peptidomimetic macrocycles for use in treatment of a solid tumor, determined to lack a p53 deactivation mutation, in a subject.
    Type: Application
    Filed: March 15, 2019
    Publication date: September 5, 2019
    Inventors: Hubert Chen, David Allen Annis, Yong Chang, Manuel Aivado, Karen Olson, Chris Viau
  • PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
    Publication number: 20190256559
    Abstract: Methods for treating liquid cancer, determined to lack a p53 deactivation mutation, in a subject are provided. Also provided are peptidomimetic macrocycles for use in treatment of a liquid cancer, determined to lack a p53 deactivation mutation, in a subject.
    Type: Application
    Filed: December 18, 2018
    Publication date: August 22, 2019
    Inventors: Hubert Chen, David Allen Annis, Yong Chang, Manuel Aivado, Karen Olson, Chris Viau
  • Peptidomimetic macrocycles and uses thereof
    Patent number: 10253067
    Abstract: Methods for treating liquid cancer, determined to lack a p53 deactivation mutation, in a subject are provided. Also provided are peptidomimetic macrocycles for use in treatment of a liquid cancer, determined to lack a p53 deactivation mutation, in a subject.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: April 9, 2019
    Assignee: Aileron Therapeutics, Inc.
    Inventors: Hubert Chen, David Allen Annis, Yong Chang, Manuel Aivado, Karen Olson, Chris Viau
  • PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
    Publication number: 20180371021
    Abstract: The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
    Type: Application
    Filed: May 9, 2018
    Publication date: December 27, 2018
    Inventors: Manuel AIVADO, Vincent GUERLAVAIS, Karen OLSON
  • COMPANION DIAGNOSTIC TOOL FOR PEPTIDOMIMETIC MACROCYCLES
    Publication number: 20170349638
    Abstract: The present invention provides diagnostic tools, systems, and methods for detecting wild type p53 and p53-associated mutations for the treatment of disease with peptidomimetic macrocycles.
    Type: Application
    Filed: March 20, 2017
    Publication date: December 7, 2017
    Inventor: Manuel Aivado
  • PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
    Publication number: 20170114098
    Abstract: Provided herein are peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease. Also provided here in are methods of using such macrocycles in combination with at least one additional pharmaceutically active agent for treatment of disorders, for example for treatment of cancer.
    Type: Application
    Filed: September 2, 2016
    Publication date: April 27, 2017
    Inventors: Manuel AIVADO, Vincent GUERLAVAIS, Karen OLSON
  • PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
    Publication number: 20160333049
    Abstract: Methods for treating liquid cancer, determined to lack a p53 deactivation mutation, in a subject are provided. Also provided are peptidomimetic macrocycles for use in treatment of a liquid cancer, determined to lack a p53 deactivation mutation, in a subject.
    Type: Application
    Filed: March 18, 2016
    Publication date: November 17, 2016
    Inventors: Hubert CHEN, David Allen ANNIS, Yong CHANG, Manuel AIVADO, kAREN OLSON, Chris VIAU
  • PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
    Publication number: 20160193283
    Abstract: Methods for treating solid tumor, determined to lack a p53 deactivation mutation, in a subject are provided. Also provided are peptidomimetic macrocycles for use in treatment of a solid tumor, determined to lack a p53 deactivation mutation, in a subject.
    Type: Application
    Filed: September 24, 2015
    Publication date: July 7, 2016
    Inventors: Hubert Chen, David Allen Annis, Yong Chang, Manuel Aivado, Karen Olson, Chris J. Viau