Patents by Inventor Manuel Garcia Algar

Manuel Garcia Algar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10987669
    Abstract: The invention relates to an apparatus and method of detecting and quantifying the number of circulating tumour cells (CTCs) and/or tumour cells (TCs) from a liquid biopsy by using a hyperoxic environment and incubation with a fluorophore-labelled metabolic indicator (fluorophore-labelled 2-D-glucose derivative) and microfluidic chips.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: April 27, 2021
    Assignees: MEDCOM TECH, S.A., FUNDACION DE INVESTIGACION HM HOSPITALES, MEDCOM ADVANCE, S.A.
    Inventors: Hainan Xie, Manuel Garcia Algar, Moritz Nazarenus, Juan Sagales, Carlos Villanueva Leal, Sara Gomez de Pedro, Eduardo Manuel Garcia Rico
  • Publication number: 20200061260
    Abstract: The present invention relates to a device and method for the preparation of platelet rich plasma, and to the plasma obtained by employing said device and method. The method comprises evaporating and dialysing plasma with the device of the invention to provide a plasma enriched in platelets and non-platelet biomolecules. The plasma thus obtained shows improved regenerative properties with respect to other plasma preparations.
    Type: Application
    Filed: May 11, 2018
    Publication date: February 27, 2020
    Inventors: Ramon Angel Alvarez-Puebla, Sara Gomez de Pedro, Manuel Garcia Algar, Moritz Julian Nazarenus, Xiaotong Feng, Mikel Sanchez Alvarez, Pello Sanchez Arizmendiarrieta, Diego Delgado San Vicente, Ane Garate Letona, Julian Alonso Chamarro, Maria del Mar Puyol Bosch, Antonio Calvo Lopez
  • Publication number: 20200055048
    Abstract: The present invention relates to a microfluidic device for the detection of circulating tumour cells (CTCs) in a fluid sample. The invention also relates to an in vitro method for the detection and/or quantification of circulating tumour cells (CTCs) in a fluid sample. Further, the invention relates to in vitro methods for (a) diagnosing a tumour and/or metastasis in a subject, and (b) determining the prognosis of a subject suffering from a tumour and/or metastasis. Finally, the invention refers to a kit comprising (a) a microfluidic device according to the first aspect of the invention, and (b) labelled probes targeting a first CTCs surface marker and, optionally, at least a second CTCs surface marker.
    Type: Application
    Filed: April 9, 2018
    Publication date: February 20, 2020
    Inventors: Ramon Angel Alvarez-Puebla, Eric Pedrol, Jaume Massons, Francisco Diaz, Manuel Garcia Algar, Moritz Julian Nazarenus, Eduardo Garcia-Rico Fernandez
  • Publication number: 20190022652
    Abstract: The invention relates to an apparatus and method of detecting and quantifying the number of circulating tumour cells (CTCs) and/or tumour cells (TCs) from a liquid biopsy by using a hyperoxic environment and incubation with a fluorophore-labelled metabolic indicator (fluorophore-labelled 2-D-glucose derivative) and microfluidic chips.
    Type: Application
    Filed: March 3, 2017
    Publication date: January 24, 2019
    Inventors: Hainan Xie, Manuel Garcia Algar, Moritz Nazarenus, Juan Sagales, Carlos Villanueva Leal, Sara Gomez de Pedro, Eduardo Manuel Garcia Rico