Patents by Inventor Maolong Lu

Maolong Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150252366
    Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.
    Type: Application
    Filed: May 15, 2015
    Publication date: September 10, 2015
    Inventors: Andrey A. Boukharov, Zijin Du, Liang Guo, Michelle C. Hresko, David K. Kovalic, Zhaolong Li, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck J. Williams, Wei Wu
  • Publication number: 20150096083
    Abstract: The present invention provides non-coding regulatory element polynucleotide molecules isolated from the lipid transfer protein (LTP) gene of Oryza sativa and useful for expressing transgenes in plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the Oryza sativa regulatory polynucleotide sequences, and methods for preparing and using the same.
    Type: Application
    Filed: July 28, 2014
    Publication date: April 2, 2015
    Inventors: Wei Wu, Qi Wang, James Morrell, Linda Lutfiyya, Maolong Lu, Zhaolong Li, Ping Li, Michelle Lacy, David Kovalic, Yongwei Cao, Andrey Boukharov, Stanislaw Flasinski, Peter T. Hajdukiewicz
  • Patent number: 8946510
    Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
    Type: Grant
    Filed: April 8, 2005
    Date of Patent: February 3, 2015
    Assignee: Monsanto Technology LLC
    Inventors: James A. Baum, Larry A. Gilbertson, David K. Kovalic, Thomas J. LaRosa, Maolong Lu, Tichafa R. I. Munyikwa, James K. Roberts, Wei Wu, Bei Zhang
  • Publication number: 20140325702
    Abstract: The present invention is directed to controlling plant pest infestation, and particularly plant nematode infestation, by inhibiting one or more biological functions in the plant pest. The invention discloses methods and compositions for use in controlling plant pest infestation by providing one or more different recombinant double stranded RNA molecules in the diet of the pest in order to achieve a reduction in pest infestation through suppression of pest gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, to methods for detecting cells comprising the disclosed sequences, and to methods for detecting the disclosed sequences in biological samples.
    Type: Application
    Filed: December 29, 2011
    Publication date: October 30, 2014
    Inventors: Andrey A. Boukharov, Zijin Du, Liang Guo, David K. Kovalic, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck Jeremy Williams, Wei Wu
  • Patent number: 8859746
    Abstract: The present invention provides non-coding regulatory element polynucleotide molecules isolated from the lipid transfer protein (LTP) gene of Oryza sativa and useful for expressing transgenes in plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the Oryza sativa regulatory polynucleotide sequences, and methods for preparing and using the same.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: October 14, 2014
    Assignee: Monsanto Technology LLC
    Inventors: Wei Wu, Qi Wang, James Morrell, Linda Lutfiyya, Maolong Lu, Zhaolong Li, Ping Li, Michelle Lacy, David Kovalic, Yongwei Cao, Andrey Boukharov, Stanislaw Flasinski, Peter T. Hajdukiewicz
  • Patent number: 8772466
    Abstract: The present invention provides non-coding regulatory element polynucleotide molecules isolated from the transcription factor Nuclear Factor B (NFB2) gene of Zea mays and useful for expressing transgenes in plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the Zea mays NFB2 regulatory polynucleotide sequences, and methods for preparing and using the same.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: July 8, 2014
    Assignee: Monsanto Technology LLC
    Inventors: Donald E. Nelson, Brendan S. Hinchey, Michelle Lacy, James A. Morrell, Andrey A. Boukharov, Zhaolong Li, Wei Wu, Linda Lutfiyya, Maolong Lu, David K. Kovalic, Qi Wang, Ping Li, Yongwei Cao
  • Patent number: 8673631
    Abstract: The present invention relates to a method of using a dicot intron or elements thereof to enhance transgene expression in plants. The present invention also provides constructs, transgenic plants and seeds containing the polynucleotide useful for expressing transgene in plants.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: March 18, 2014
    Assignee: Monsanto Technology LLC
    Inventors: Stanislaw Flasinski, Christopher Hubmeier, Maolong Lu, Marianne Malven, Wei Wu
  • Publication number: 20140004088
    Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.
    Type: Application
    Filed: August 27, 2013
    Publication date: January 2, 2014
    Applicant: Monsanto Technology LLC
    Inventors: Andrey A. Boukharov, Zijin Du, Liang Guo, Michelle C. Hresko, David K. Kovalic, Zhaolong Li, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck J. Williams, Wei Wu
  • Publication number: 20130232646
    Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
    Type: Application
    Filed: March 1, 2013
    Publication date: September 5, 2013
    Applicant: Monsanto Technology LLC
    Inventors: James A. Baum, Larry A. Gilbertson, David K. Kovalic, Thomas J. LaRosa, Maolong Lu, Tichafa R.I. Munyikwa, James K. Roberts, Wei Wu, Bei Zhang
  • Patent number: 8519225
    Abstract: The invention relates to identifying and evaluating target coding sequences for control of plant parasitic nematodes by inhibiting one or more biological functions, and their use. The invention provides methods and compositions for identification of such sequences and for the control of a plant-parasitic nematode population. By feeding one or more recombinant double stranded RNA molecules provided by the invention to the nematode, a reduction in disease may be obtained through suppression of nematode gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: February 9, 2007
    Date of Patent: August 27, 2013
    Assignee: Monsanto Technology LLC
    Inventors: Andrey A. Boukharov, Zijin Du, Liang Guo, Michelle C. Hresko, David K. Kovalic, Zhaolong Li, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck J. Williams, Wei Wu
  • Publication number: 20120164205
    Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
    Type: Application
    Filed: September 6, 2011
    Publication date: June 28, 2012
    Inventors: James A. Baum, Larry A. Gilbertson, David K. Kovalic, Thomas J. LaRosa, Maolong Lu, Tichafa R. I. Munyikwa, James K. Roberts, Wei Wu, Bei Zhang
  • Publication number: 20120131694
    Abstract: The present invention relates to a method of using a dicot intron or elements thereof to enhance transgene expression in plants. The present invention also provides constructs, transgenic plants and seeds containing the polynucleotide useful for expressing transgene in plants.
    Type: Application
    Filed: October 24, 2011
    Publication date: May 24, 2012
    Inventors: Stanislaw Flasinski, Christopher Hubmeier, Maolong Lu, Marianne Malven, Wei Wu
  • Publication number: 20120090051
    Abstract: Plant nitrogen use efficiency in corn has been improved by transformation with a flavohemoglobin gene. Plants comprising a flavohemoglobin gene have decreased nitric oxide (NO) levels, increased biomass accumulation under a sufficient nitrogen growth condition, and increased chlorophyll content under a limiting nitrogen growth condition. Additionally, these transformed plants evidence higher levels of yield.
    Type: Application
    Filed: October 4, 2010
    Publication date: April 12, 2012
    Inventors: Amarjit Basra, Mike Edgerton, Garrett J. Lee, Maolong Lu, Linda L. Lutfiyya, Wei Wu, Xiaoyun Wu
  • Patent number: 8088976
    Abstract: The present invention is directed to controlling plant pest infestation, and particularly plant nematode infestation, by inhibiting one or more biological functions in the plant pest. The invention discloses methods and compositions for use in controlling plant pest infestation by providing one or more different recombinant double stranded RNA molecules in the diet of the pest in order to achieve a reduction in pest infestation through suppression of pest gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, to methods for detecting cells comprising the disclosed sequences, and to methods for detecting the disclosed sequences in biological samples.
    Type: Grant
    Filed: February 23, 2006
    Date of Patent: January 3, 2012
    Assignee: Monsanto Technology LLC
    Inventors: Andrey A. Boukharov, Zijin Du, Liang Guo, David K. Kovalic, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck Jeremy Williams, Wei Wu
  • Patent number: 8067671
    Abstract: The present invention is directed to controlling plant pest infestation, and particularly plant nematode infestation, by inhibiting one or more biological functions in the plant pest. The invention discloses methods and compositions for use in controlling plant pest infestation by providing one or more different recombinant double stranded RNA molecules in the diet of the pest in order to achieve a reduction in pest infestation through suppression of pest gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, to methods for detecting cells comprising the disclosed sequences, and to methods for detecting the disclosed sequences in biological samples.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: November 29, 2011
    Assignee: Monsanto Technology LLC
    Inventors: Andrey A. Boukharov, Zijin Du, Liang Guo, David K. Kovalic, Maolong Lu, James P. McCarter, Nancy M. Miller, Mark Vaudin, Deryck Jeremy Williams, Wei Wu
  • Publication number: 20110078833
    Abstract: The present invention provides non-coding regulatory element polynucleotide molecules isolated from the lipid transfer protein (LTP) gene of Oryza sativa and useful for expressing transgenes in plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the Oryza sativa regulatory polynucleotide sequences, and methods for preparing and using the same.
    Type: Application
    Filed: September 17, 2010
    Publication date: March 31, 2011
    Inventors: Wei WU, Qi WANG, James MORRELL, Linda LUTFIYYA, Maolong LU, Zhaolong LI, Ping LI, Michelle LACY, David KOVALIC, Yongwei CAO, Andrey BOUKHAROV, Stanislaw FLASINSKI, Peter T. HAJDUKIEWICZ
  • Patent number: 7816510
    Abstract: The present invention provides non-coding regulatory element polynucleotide molecules isolated from Zea mays useful for expressing transgenes in plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the Zea mays regulatory polynucleotide sequences, and methods for preparing and using the same.
    Type: Grant
    Filed: December 31, 2008
    Date of Patent: October 19, 2010
    Assignee: Monsanto Technology LLC
    Inventors: Wei Wu, Qi Wang, James Morrell, Linda Lutfiyya, Maolong Lu, Zhaolong Li, Ping Li, Michelle Lacy, David Kovalic, Yongwei Cao, Andrey Boukharov, Stanislaw Flasinski, Peter T. Hajdukiewicz
  • Patent number: 7812219
    Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
    Type: Grant
    Filed: November 30, 2007
    Date of Patent: October 12, 2010
    Assignee: Monsanto Technology LLC
    Inventors: James A. Baum, Larry A. Gilbertson, David K. Kovalic, Thomas J. LaRosa, Maolong Lu, Tichafa R. I. Munyikwa, James K. Roberts, Wei Wu, Bei Zhang
  • Publication number: 20090307803
    Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
    Type: Application
    Filed: April 8, 2005
    Publication date: December 10, 2009
    Inventors: James A. Baum, Larry A. Gilbertson, David K. Kovalic, Thomas J. LaRosa, Maolong Lu, Tichafa R.I. Munyikwa, James K. Roberts, Wei Wu, Bei Zhang
  • Patent number: 7629455
    Abstract: The present invention provides non-coding regulatory element polynucleotide molecules isolated from the transcription factor Nuclear Factor B (NFB2) gene of Zea mays and useful for expressing transgenes in plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the Zea mays NFB2 regulatory polynucleotide sequences, and methods for preparing and using the same.
    Type: Grant
    Filed: June 20, 2007
    Date of Patent: December 8, 2009
    Assignee: Monsanto Technology LLC
    Inventors: Donald E. Nelson, Brendan S. Hinchey, Michelle Lacy, James A. Morrell, Andrey A. Boukharov, Zhaolong Li, Wei Wu, Linda Lutfiyya, Maolong Lu, David K. Kovalic, Qi Wang, Ping Li, Yongwei Cao