Patents by Inventor Marat Karpeisky

Marat Karpeisky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7598246
    Abstract: The present invention provides novel bisphosphonate conjugates, pharmaceutical compositions comprising bisphosphonate conjugates and methods of using such analogs in the treatment of bone cancer, bone-related diseases and diseases of the soft tissues surrounding bones.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: October 6, 2009
    Assignee: MBC Pharma, Inc.
    Inventors: H.B.F. Dixon, Marat Karpeisky, Alexander Karpeisky, legal representative, Nelly Padioukova, Sergey Mikhailov, Grigorii Tzeitline
  • Patent number: 6896871
    Abstract: The present invention is directed to particular bisphosphonate compounds, and in particular, to bisphosphonate conjugates that are useful in the treatment of soft tissues surrounding bone and bone-related diseases, such as bone cancer and osteoporosis.
    Type: Grant
    Filed: April 10, 2001
    Date of Patent: May 24, 2005
    Assignee: MBC Research, Inc.
    Inventors: Alexander Karpeisky, Nelly Padioukova, Sergey Mikhailov, H.B.F. Dixon, Grigorii Tzeitline, Marat Karpeisky
  • Publication number: 20050026864
    Abstract: The present invention provides novel bisphosphonate conjugates, pharmaceutical compositions comprising bisphosphonate conjugates and methods of using such analogs in the treatment of bone cancer, bone-related diseases and diseases of the soft tissues surrounding bones.
    Type: Application
    Filed: December 18, 2003
    Publication date: February 3, 2005
    Inventors: H.B.F. Dixon, Marat Karpeisky, Alexander Karpeisky, Nelly Padioukova, Sergey Mikhailov, Grigorii Tzeitline
  • Publication number: 20020142994
    Abstract: The present invention is directed to particular bisphosphonate compounds, and in particular, to bisphosphonate conjugates that are useful in the treatment of soft tissues surrounding bone and bone-related diseases, such as bone cancer and osteoporosis.
    Type: Application
    Filed: April 10, 2001
    Publication date: October 3, 2002
    Inventors: Marat Karpeisky, Nelly Padioukova, Sergey Mikhailov, H.B.F. Dixon, Grigorii Tzeitline
  • Patent number: 6214812
    Abstract: Bisphosphonate conjugates capable of releasing antibacterial and/or cytotoxic components upon binding with bone tissue. Such conjugates are useful in the treatment and prevention of bone cancer, bone infections and other bone-related diseases. Bisphosphonate conjugates are also delivery vehicles for use in delivering pharmaceutical compositions to bone tissue. Methods of synthesizing novel bisphosphonates and pharmaceutical compositions incorporating the same, and medical uses for such compositions, are provided. Compositions of the present invention include bone-seeking radio isotope conjugates for use in imaging and therapy.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: April 10, 2001
    Assignee: MBC Research, Inc.
    Inventors: Marat Karpeisky, Nelly Padioukova, Sergey Mikhailov, H. B. F. Dixon, Grigorii Tzeitline
  • Patent number: 6103881
    Abstract: Certain toxic compounds (T) such as, for example, compounds based upon diphtheria toxin, ricin toxin, pseudomonas exotoxin, .alpha.-amanitin, pokeweed antiviral protein (PAP), ribosome inhibiting proteins, especially the ribosome inhibiting proteins of barley, wheat, corn, rye, gelonin and abrin, as well as certain cytotoxic chemicals such as, for example, melphalan and daunomycin can be conjugated to certain analogs of gonadotropin-releasing hormone to form a class of compounds which, when injected into an animal, destroy the gonadotrophs of the animal's anterior pituitary gland. Hence such compounds may be used to sterilize such animals and/or to treat certain sex hormone related diseases.
    Type: Grant
    Filed: April 7, 1998
    Date of Patent: August 15, 2000
    Assignee: Colorado State University Research Foundation
    Inventors: Torrance M. Nett, Leonard Michael Glode, Marat Karpeisky
  • Patent number: 5786457
    Abstract: Certain toxic compounds (T) such as, for example, compounds based upon diphtheria toxin, ricin toxin, pseudomonas exotoxin, .alpha.-amanitin, pokeweed antiviral protein (PAP), ribosome inhibiting proteins, especially the ribosome inhibiting proteins of barley, wheat, corn, rye, gelonin and abrin, as well as certain cytotoxic chemicals such as, for example, melphalan and daunomycin can be conjugated to certain analogs of gonadotropin-releasing hormone to form a class of compounds which, when injected into an animal, destroy the gonadotrophs of the animal's anterior pituitary gland. Hence such compounds may be used to sterilize such animals and/or to treat certain sex hormone related diseases.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 28, 1998
    Assignee: Colorado State University Research Foundation
    Inventors: Torrance M. Nett, Leonard Michael Glode, Marat Karpeisky