Patents by Inventor Marc A. Giulianotti

Marc A. Giulianotti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neurite outgrowth promoters and uses thereof
    Patent number: 11981660
    Abstract: Provided herein are compounds useful in treating a central nervous system disorder associated with neuronal and/or axonal damage, methods for their preparation, and related pharmaceutical compositions. For example provided herein are compounds of Formula (I): and pharmaceutically acceptable salts and compositions including the same.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: May 14, 2024
    Assignees: UNIVERSITY OF MIAMI, Torrey Pines Institute for Molecular Studies
    Inventors: Vance Lemmon, Hassan Al-Ali, John Bixby, Marc Giulianotti
  • Melanocortin ligands and methods of use thereof
    Patent number: 10899793
    Abstract: Certain embodiments of the invention provide a compound of formula (I): R1—C(?O)—W—X—Y—Z—N(R2)2??(I) or a salt thereof, wherein R1, R2, W, X, Y and Z are as defined herein, as well as methods of use thereof.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: January 26, 2021
    Assignees: Regents of the University of Minnesota, Torrey Pines Institute for Molecular Studies
    Inventors: Carrie Haskell-Luevano, Skye Ross Doering, Jon R. Appel, Marc A. Giulianotti, Richard A. Houghten, Clemencia Pinilla, Radleigh G. Santos
  • NEURITE OUTGROWTH PROMOTERS AND USES THEREOF
    Publication number: 20210017162
    Abstract: Provided herein are compounds useful in treating a central nervous system disorder associated with neuronal and/or axonal damage, methods for their preparation, and related pharmaceutical compositions. For example provided herein are compounds of Formula (I): and pharmaceutically acceptable salts and compositions including the same.
    Type: Application
    Filed: March 21, 2019
    Publication date: January 21, 2021
    Inventors: Vance Lemmon, Hassan Al-Ali, John Bixby, Marc Giulianotti
  • High-affinity small molecule formylpeptide receptor ligands from screening of combinatorial mixture-based libraries
    Patent number: 10048272
    Abstract: The present invention provides novel methods and assays for high-throughput screening of combinatorial libraries to identify FPR1 and/or FPR2 ligands (e.g., agonists and/or antagonists), preferably FPR1 agonists and/or FPR2 antagonists, by positional scanning deconvolution. The invention also provides novel FPR1 and FPR2 ligands (e.g, agonists and antagonists), related pharmaceutical compositions and methods of treating FPR1 and FPR2-related disorders.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: August 14, 2018
    Assignees: STC.UNM, Torrey Pines Institute for Molecular Studies
    Inventors: Bruce S. Edwards, Larry A. Sklar, Clemencia Pinilla, Richard A. Houghten, Jon R. Appel, Marc A. Giulianotti, Jose Medina-Franco
  • MELANOCORTIN LIGANDS AND METHODS OF USE THEREOF
    Publication number: 20170342107
    Abstract: Certain embodiments of the invention provide a compound of formula (I): R1—C(?O)—W—X—Y—Z—N(R2)2 ??(I) or a salt thereof, wherein R1, R2, W, X, Y and Z are as defined herein, as well as methods of use thereof.
    Type: Application
    Filed: May 25, 2017
    Publication date: November 30, 2017
    Inventors: Carrie Haskell-Luevano, Skye Ross Doering, Jon R. Appel, Marc A. Giulianotti, Richard A. Houghten, Clemencia Pinilla, Radleigh G. Santos
  • HIGH-AFFINITY SMALL MOLECULE FORMYLPEPTIDE RECEPTOR LIGANDS FROM SCREENING OF COMBINATORIAL MIXTURE-BASED LIBRARIES
    Publication number: 20160320402
    Abstract: The present invention provides novel methods and assays for high-throughput screening of combinatorial libraries to identify FPR1 and/or FPR2 ligands (e.g., agonists and/or antagonists), preferably FPR1 agonists and/or FPR2 antagonists, by positional scanning deconvolution. The invention also provides novel FPR1 and FPR2 ligands (e.g, agonists and antagonists), related pharmaceutical compositions and methods of treating FPR1 and FPR2-related disorders.
    Type: Application
    Filed: February 2, 2016
    Publication date: November 3, 2016
    Inventors: Bruce S. Edwards, Larry A. Sklar, Clemencia Pinilla, Richard A. Houghten, Jon R. Appel, Marc A. Giulianotti, Jose Medina-Franco
  • High-affinity small molecule formylpeptide receptor ligands from screening of combinatorial mixture-based libraries
    Patent number: 9310364
    Abstract: The present invention provides novel methods and assays for high-throughput screening of combinatorial libraries to identify FPR1 and/or FPR2 ligands (e.g., agonists and/or antagonists), preferably FPR1 agonists and/or FPR2 antagonists, by positional scanning deconvolution. The invention also provides novel FPR1 and FPR2 ligands (e.g, agonists and antagonists), related pharmaceutical compositions and methods of treating FPR1 and FPR2-related disorders.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: April 12, 2016
    Assignees: STC.UNM, TORREY PINES INSTITUTE FOR MOLECULAR STUDIES
    Inventors: Bruce S. Edwards, Larry A. Sklar, Clemencia Pinilla, Richard A. Houghten, Jon R. Appel, Marc A. Giulianotti, Jose Medina-Franco