Abstract: The present invention relates to novel anti-NaPi2b antibodies, antibody-drug-conjugates (ADCs) based thereon as well as to therapeutic methods and uses thereof, particularly in relation to cancer treatment.

Abstract: The wheel chock includes a locking mechanism that can be held in a locked state when properly positioned on a base plate. The locking mechanism includes a positioning unit having at least one tooth provided to engage a side of a corresponding one of the blocking elements in a latched engagement when the positioning unit is in the fully locked position. The locking mechanism also includes an actuating device to move the positioning unit from the unlocked position towards the fully locked position, and a holding device to selectively hold the positioning unit in the fully locked position.

Abstract: An exemplary method of imaging tissue of a subject using a rolling shutter imager to provide a video stream comprises: sequentially resetting a plurality of rows of pixels of the rolling shutter imager from a first row to a last row; transitioning a liquid crystal shutter from a closed state to an open state; after the liquid crystal shutter is transitioned into the open state and after resetting the last row, illuminating the tissue of the subject with an illumination light for an illumination period to accumulate charge at the plurality of rows of pixels, and after the illumination period ends, sequentially reading the accumulated charge at the rows of pixels from the first row to the last row; generating an image frame from the sequentially read accumulated charge at the plurality of rows of pixels; and adding the image frame to the video stream.

Abstract: A method of tracking 3D position and orientation of an entity in a moving platform is described. The method comprises receiving data sensed by an inertial measurement unit mounted on the entity. Visual tracking data is also received, computed from images depicting the moving platform or the entity in the moving platform. The method computes the 3D position and orientation of the entity by estimating a plurality of states using the visual tracking data and the data sensed by the inertial measurement unit, where the states comprise both states of the moving platform and states of the entity.

Abstract: The present invention provides a method for in-situ etching of a wafer prior to sputter deposition, the method comprising the following steps. A sputtering chamber having a sputtering target is provided. The wafer is placed into the sputtering chamber. A gas is introduced into the sputtering chamber such that the gas at least partially ionized as a plasma, wherein the plasma includes positively charged gas ions. A first negative potential is applied to the wafer while a second negative potential is simultaneously applied to the sputtering target and while no shutter is positioned between the wafer and the sputtering target.

Abstract: Nucleic acids encoding norovirus VP1 fusion proteins and VLPs comprising the norovirus VP1 fusion proteins are provided. Methods for norovirus VP1 fusion protein and norovirus VLP production in plants are also described. The VP1 fusion protein comprises, a first sequence encoding an S domain derived from a first norovirus strain, and a second sequence encoding a P domain derived from a second norovirus strain.

Abstract: The present disclosure provides a system, apparatus and method for providing rapid shutdown for photovoltaic power systems and provides a system, apparatus and method for providing arc sensing for photovoltaic power systems. An AC current can be put on the DC bus to control PV panel shutdown. Local mean decomposition can be used to sense arcing on the DC bus.

Abstract: Determining a location of an entity comprises: receiving a query comprising a 2D image depicting an environment of the entity; searching for a match between the query and a 3D map of the environment. The 3D map comprising a 3D point cloud, the match indicating the location of the entity in the environment. Searching for the match comprises: extracting descriptors from the 2D image referred to as image descriptors; extracting descriptors from the 3D point cloud referred to as point cloud descriptors; correlating the image descriptors with the point cloud descriptors to produce correspondences, wherein a correspondence is an image descriptor corresponding to a point cloud descriptor; estimating, using the correspondences, the location of the entity.

Abstract: Systems and methods are disclosed for processing data associated with isolated execution environments. A chunk of data associated with an isolated execution environment can include log data and non-log data. At least a portion of the log data can include log data generated by the isolated execution environment. The system can parse the chunk of data to identify the log data and the non-log data and extract at least a portion of the log data from the chunk of data. The extracted data can be further processed to generate one or more events.

Abstract: A silicone-polyolefin composition is disclosed. The silicone-polyolefin composition comprises (A) a polysiloxane, (B) a functionalized polyolefin, and (C) a curable silicone elastomer component. The polysiloxane (A) comprises an average of at least one functional group X per molecule, and the functionalized polyolefin (B) comprises an average of at least one functional group Y per molecule, where the functional group X and functional group Y are reactable to form a bond therebetween. A silicone-polyolefin blend, a curable composition comprising the silicone-polyolefin blend, a cured product of the curable composition, and methods of preparing the silicone-polyolefin blend, curable composition, and cured product are also disclosed.

Abstract: In example embodiments, techniques are provided for classifying elements of infrastructure models using a convolutional graph neural network (GNN). Graph-structured data structures are generated from infrastructure models, in which nodes represent elements and edges represent contextual relationships among elements (e.g., based on proximity, functionality, parent-child relationships, etc.). During training, the GNN learns embeddings from the nodes and edges of the graph-structured data structures, the embeddings capturing contextual clues that distinguish between elements that may share similar geometry (e.g., cross section, volume, surface area, etc.), yet serve different purposes.

Abstract: A composition and a method for preparing a polymer composite article. The composition comprises (A) a filler in an amount of from 10 to 90 wt. The composition also comprises (B) a polymer in an amount of from 10 to 90 wt. %. wherein the (B) polymer is selected from polyolefins, polyamides, polyesters, or combinations thereof. Further, the composition comprises (C) an organopolysiloxane in an amount of from greater than 0 to 10 wt. %; the (C) organopolysiloxane having at least one silicon-bonded hydroxyl group and a viscosity of from 1,000 to 60,000 mPa·s at 25° C. The ranges for components (A)-(C) arc based on the total weight of components (A), (B) and (C) in the composition.

Abstract: Earpieces and methods for acute sound detection and reproduction are provided. A method can include measuring an external ambient sound level (xASL), monitoring a change in the xASL for detecting an acute sound, estimating a proximity of the acute sound, and upon detecting the acute sound and its proximity, reproducing the acute sound within an ear canal, where the ear canal is at least partially occluded by an earpiece. Other embodiments are disclosed.

Abstract: A method for synthesizing a protein of interest within a plant or a portion of a plant is provided. The method involves treating the plant to increase secondary leaf biomass production, followed by introducing one or more than one nucleic acid sequence encoding a protein of interest operatively linked with a regulatory region that is active in the plant, into the plant. The plant is then maintained under conditions that permit the nucleic acid sequence encoding the protein of interest to be expressed in the plant or the portion of the plant. Optionally, the plant or portion of the plant may be harvested and the protein of interest extracted.

Abstract: The application relates to a process for the preparation of a compound of formula (II) by cyclisation of a polyene of formula (I), and to an intermediate of formula (III). The obtained compounds are useful intermediates in the preparation of specific isoprenoids, preferably in the production of vitamin A and derivatives of vitamin A.

Abstract: In example embodiments, techniques are provided that use two different ML models (a symbol association ML model and a link association ML model), one to extract associations between text labels and one to extract associations between symbols and links, in a schematic diagram (e.g., P&ID) in an image-only format. The two models may use different ML architectures. For example, the symbol association ML model may use a deep learning neural network architecture that receives for each possible text label and symbol pair both a context and a request, and produces a score indicating confidence the pair is associated. The link association ML model may use a gradient boosting tree architecture that receives for each possible text label and link pair a set of multiple features describing at least the geometric relationship between the possible text label and link pair and produces a score indicating confidence the pair is associated.

Abstract: A composition includes a crosslinked polysiloxane elastomer with 2 or more carbon-oxygen-silicon linkages between a polysaccharide component and polysiloxane component, where the polysaccharide component is other than a cellulose or starch component.

Abstract: A barrier for a roadway (e.g., a highway, bridge, or other road), which can be used to manage vehicular traffic, such as to establish lanes, protect motorists and other people (e.g., pedestrians, constructions workers, etc.) against crashes or other impacts, and/or other purposes, and which may be configured to enhance its use and performance, such as by better protecting the motorists and others when impacted by vehicles (e.g., reducing deflection by deflecting less or substantially not deflecting and/or otherwise improving protection provided by the barrier), facilitating transportation, installation, removal, and/or transfer of the barrier at the roadway, and/or enhancing other aspects of the barrier. For example, the barrier may be designed to protect against (e.g., prevent or reduce) deformation, breakage and/or other deterioration of interfaces (e.g., connections and/or interfacing material) of components of the barrier that may move relative to one another (e.g., when impacted by vehicles).

Abstract: In example embodiments, techniques are provided for labeling elements of an infrastructure model with classes. The techniques may be implemented by a labeling tool that uses an ML model to create element selections and provides a cycle review mode to speed review within such selections. The labeling tool may further provide for two file loading and a number of visualization schemes to speed comparison of label files and prediction files.

Abstract: The present disclosure provides a bidirectional power converter capable of receiving and delivering AC and DC power from and to multiple ports in accordance to its different embodiments. The AC or DC input receives power and at least two power conversion circuits work with a plurality of switches for connecting provides DC or AC current at multiple ports. The power conversion circuits may be rectifier inverters and have module form that connect to the AC and DC ports via a backplane having multiple connectors. The apparatus may also provide DC to DC conversion using a buck/boost circuit.