Patents by Inventor Marc C. Torjman

Marc C. Torjman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230123995
    Abstract: A method of monitoring physiological conditions including an acoustic measurement device and a remote controller. The remove controller configured to measure physiological conditions; calculate absolute tidal volume, a direction of tidal volume, and a rate of change of tidal volume; correlate absolute tidal volume, a direction of tidal volume, and a rate of change of tidal volume to a risk score; calculate a direction trend and rate of change for each physiological condition; correlate the direction trend and rate of change for each physiological condition; detect predefined patterns in the direction trend and rate of change of the measured physiological condition at the predetermined interval; and generating at least one from the group consisting of an alert, an alarm, and a medical treatment if the risk score defined on the predefined scale exceeds a first predetermined risk score threshold and at least one predefined pattern is detected.
    Type: Application
    Filed: December 15, 2022
    Publication date: April 20, 2023
    Inventors: Jeffrey I. JOSEPH, Noud Van HELMOND, Marc C. TORJMAN, Denise L. DEVINE, Nance K. DICCIANI, Channy LOEUM
  • Patent number: 11529076
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Grant
    Filed: October 11, 2021
    Date of Patent: December 20, 2022
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I Joseph, Noud Van Helmond, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
  • Publication number: 20220022773
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: October 11, 2021
    Publication date: January 27, 2022
    Inventors: Jeffrey I JOSEPH, Noud Van HELMOND, Marc C TORJMAN, Denise L DEVINE, Nance K DICCIANI, Channy LOEUM
  • Patent number: 11213225
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: January 4, 2022
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I Joseph, Noud Van Helmond, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
  • Publication number: 20210251520
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: May 5, 2021
    Publication date: August 19, 2021
    Inventors: Jeffrey I JOSEPH, Noud Van HELMOND, Marc C TORJMAN, Denise L DEVINE, Nance K DICCIANI, Channy LOEUM
  • Patent number: 11071476
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: July 27, 2021
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I Joseph, Noud Van Helmond, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
  • Patent number: 11006863
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Grant
    Filed: February 27, 2020
    Date of Patent: May 18, 2021
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I Joseph, Noud Van Helmond, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
  • Patent number: 11000191
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: May 11, 2021
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I Joseph, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
  • Patent number: 11000212
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: May 11, 2021
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I Joseph, Noud Van Helmond, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
  • Patent number: 10881330
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: January 5, 2021
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I Joseph, Noud Van Helmond, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
  • Publication number: 20200375502
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: August 18, 2020
    Publication date: December 3, 2020
    Inventors: Jeffrey I. JOSEPH, Noud Van HELMOND, Marc C. TORJMAN, Denise L DEVINE, Nance K DICCIANI, Channy LOEUM
  • Patent number: 10842416
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: November 24, 2020
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Jeffrey I Joseph, Noud Van Helmond, Marc C Torjman, Denise L Devine, Nance K Dicciani, Channy Loeum
  • Publication number: 20200360393
    Abstract: The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine , or other stereoisomeric dehydro or hydroxylated ketamine metabolite. (2R,6R)-Hydroxynorketamine The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain synthetic pain disorder (CRPD) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment.
    Type: Application
    Filed: July 31, 2020
    Publication date: November 19, 2020
    Inventors: IRVING W. WAINER, RUIN MOADDEL, MICHEL BERNIER, CARLOS A. ZARATE, MARC C. TORJMAN, MICHAEL E. GOLDBERG, MARY J. TANGA
  • Publication number: 20200352456
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: July 24, 2020
    Publication date: November 12, 2020
    Inventors: Jeffrey I. Joseph, Marc C. Torjman, Denise L. Devine, Nance K. Dicciani, Channy Loeum
  • Publication number: 20200196911
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: February 27, 2020
    Publication date: June 25, 2020
    Inventors: Jeffrey I. JOSEPH, Noud Van HELMOND, Marc C. TORJMAN, Denise L. DEVINE, Nance K. DICCIANI, Channy LOEUM
  • Publication number: 20200054277
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: August 19, 2019
    Publication date: February 20, 2020
    Inventors: Jeffrey I. JOSEPH, Noud Van HELMOND, Marc C. TORJMAN, Denise L. DEVINE, Nance K. DICCIANI, Channy LOEUM
  • Publication number: 20200054250
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: August 22, 2019
    Publication date: February 20, 2020
    Inventors: Jeffrey I. JOSEPH, Noud Van HELMOND, Marc C. TORJMAN, Denise L. DEVINE, Nance K. DICCIANI, Channy LOEUM
  • Publication number: 20200054278
    Abstract: A method of monitoring respiration with an acoustic measurement device, the acoustic measurement device having a sound transducer, the sound transducer configured to measure sound associated with airflow through a mammalian trachea, the method includes correlating the measured sound into a measurement of tidal volume and generating at least one from the group consisting of an alert and an alarm if the measured tidal volume falls outside of a predetermined range.
    Type: Application
    Filed: August 22, 2019
    Publication date: February 20, 2020
    Inventors: Jeffrey I JOSEPH, Noud Van HELMOND, Marc C TORJMAN, Denise L DEVINE, Nance K DICCIANI, Channy LOEUM
  • Publication number: 20180098993
    Abstract: The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro or hydroxylated ketamine metabolite. The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain synthetic pain disorder (CRPD) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment.
    Type: Application
    Filed: December 8, 2017
    Publication date: April 12, 2018
    Inventors: IRVING W. WAINER, RUIN MOADDEL, MICHEL BERNIER, CARLOS A. ZARATE, MARC C. TORJMAN, MICHAEL E. GOLDBERG, MARY J. TANGA
  • Patent number: 9867830
    Abstract: The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro or hydroxylated ketamine metabolite. (2R,6R)-hydroxynorketamine The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain synthetic pain disorder (CRPD) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: January 16, 2018
    Assignees: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH, COOPER HEALTH SYSTEM, SRI INTERNATIONAL
    Inventors: Irving W. Wainer, Ruin Moaddel, Michel Bernier, Carlos A. Zarate, Marc C. Torjman, Michael E. Goldberg, Mary J. Tanga