Patents by Inventor Marc Evanchik

Marc Evanchik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20230405016
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatopepatitis (NASH).
    Type: Application
    Filed: January 4, 2023
    Publication date: December 21, 2023
    Inventors: Douglas I. Buckley, Gregory Duke, Allan S. Wagman, Marc Evanchik, Robert S. Mcdowell
  • PYRIMIDINEDIONE COMPOUNDS
    Publication number: 20230165860
    Abstract: Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds and pharmaceutically acceptable salts thereof, are described, as well as methods for treating HCM and other forms of heart disease.
    Type: Application
    Filed: January 27, 2023
    Publication date: June 1, 2023
    Inventors: Johan OSLOB, Robert Anderson, Danielle Aubele, Marc Evanchik, Jonathan Charles Fox, Brian Kane, Puping Lu, Robert McDowell, Hector Rodriguez, Yonghong Song, Arvinder Sran
  • Heterocyclic modulators of lipid synthesis
    Patent number: 11622968
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
    Type: Grant
    Filed: April 2, 2020
    Date of Patent: April 11, 2023
    Assignee: Sagimet Biosciences Inc.
    Inventors: Douglas Buckley, Gregory Duke, Allan S. Wagman, Marc Evanchik, Robert S. McDowell
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20220340556
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by dysregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
    Type: Application
    Filed: May 4, 2021
    Publication date: October 27, 2022
    Inventors: Douglas BUCKLEY, Gregory DUKE, Allan S. WAGMAN, Marc EVANCHIK, Robert S. MCDOWELL
  • TREATMENT OF HCM WITH PYRIMIDINEDIONE COMPOUNDS
    Publication number: 20220313695
    Abstract: Provided are methods for treating hypertrophic cardiomyopathy and diastolic dysfunction.
    Type: Application
    Filed: June 16, 2022
    Publication date: October 6, 2022
    Inventors: Marc J. Semigran, June H. Lee, Joseph Lambing, Eric Green, Marc Evanchik, Timothy Carlson, David Zhang
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20220296605
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
    Type: Application
    Filed: April 2, 2020
    Publication date: September 22, 2022
    Inventors: Douglas BUCKLEY, Gregory DUKE, Allan S. WAGMAN, Marc EVANCHIK, Robert S. MCDOWELL
  • TREATMENT OF HCM WITH PYRIMIDINEDIONE COMPOUNDS
    Publication number: 20220226324
    Abstract: Provided are methods for treating hypertrophic cardiomyopathy and diastolic dysfunction.
    Type: Application
    Filed: March 23, 2022
    Publication date: July 21, 2022
    Inventors: Marc J. Semigran, June H. Lee, Joseph Lambing, Eric Green, Marc Evanchik, Timothy Carlson, David Zhang
  • PYRIMIDINEDIONE COMPOUNDS
    Publication number: 20210346379
    Abstract: Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds and pharmaceutically acceptable salts thereof, are described, as well as methods for treating HCM and other forms of heart disease.
    Type: Application
    Filed: January 13, 2021
    Publication date: November 11, 2021
    Inventors: Johan Oslob, Robert Anderson, Danielle Aubele, Marc Evanchik, Jonathan Charles Fox, Brian Kane, Puping Lu, Robert McDowell, Hector Rodriguez, Yonghong Song, Arvinder Sran
  • Heterocyclic modulators of lipid synthesis
    Patent number: 11034690
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: June 15, 2021
    Assignee: Saginiet Biosciences Inc.
    Inventors: Douglas I. Buckley, Gregory Duke, Allan S. Wagman, Marc Evanchik, Robert S. McDowell
  • PYRIMIDINEDIONE COMPOUNDS
    Publication number: 20200297726
    Abstract: Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds and pharmaceutically acceptable salts thereof, are described, as well as methods for treating HCM and other forms of heart disease.
    Type: Application
    Filed: June 5, 2020
    Publication date: September 24, 2020
    Inventors: Johan Oslob, Robert Anderson, Danielle Aubele, Marc Evanchik, Jonathan Charles Fox, Brian Kane, Puping Lu, Robert McDowell, Hector Rodriguez, Yonghong Song, Arvinder Sran
  • TREATMENT OF HCM WITH PYRIMIDINEDIONE COMPOUNDS
    Publication number: 20200054636
    Abstract: Provided are methods for treating hypertrophic cardiomyopathy and diastolic dysfunction.
    Type: Application
    Filed: March 26, 2019
    Publication date: February 20, 2020
    Inventors: Marc J. Semigran, June H. Lee, Joseph Lambing, Eric Green, Marc Evanchik
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20190308969
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
    Type: Application
    Filed: November 13, 2017
    Publication date: October 10, 2019
    Inventors: Douglas I. BUCKLEY, Gregory DUKE, Allan S. WAGMAN, Marc EVANCHIK, Robert S. MCDOWELL
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20190269694
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).
    Type: Application
    Filed: October 11, 2018
    Publication date: September 5, 2019
    Inventors: Douglas I. BUCKLEY, Gregory DUKE, Allan S. WAGMAN, Marc EVANCHIK, Robert S. MCDOWELL
  • Heterocyclic modulators of lipid synthesis and combinations thereof
    Patent number: 10226449
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: March 12, 2019
    Assignee: 3-V Biosciences, Inc.
    Inventors: Timothy Sean Heuer, Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Gregory Duke, Yamini Ohol-Gupta, Marie O'Farrell
  • Heterocyclic modulators of lipid synthesis
    Patent number: 10189822
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: January 29, 2019
    Assignee: 3-V Biosciences, Inc.
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Gregory Duke, Yamini Ohol-Gupta, Timothy Sean Heuer, Marie O'Farrell
  • Heterocyclic modulators of lipid synthesis
    Patent number: 10118913
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: November 6, 2018
    Assignee: 3-V Biosciences, Inc.
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Allan S. Wagman
  • PYRIMIDINEDIONE COMPOUNDS
    Publication number: 20180311242
    Abstract: Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds and pharmaceutically acceptable salts thereof, are described, as well as methods for treating HCM and other forms of heart disease.
    Type: Application
    Filed: February 15, 2018
    Publication date: November 1, 2018
    Inventors: JOHAN OSLOB, Robert Anderson, Danielle Aubele, Marc Evanchik, Jonathan Charles Fox, Brian Kane, Puping Lu, Robert McDowell, Hector Rodriguez, Yonghong Song, Arvinder Sran
  • Heterocyclic modulators of lipid synthesis
    Patent number: 10053450
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.
    Type: Grant
    Filed: July 5, 2016
    Date of Patent: August 21, 2018
    Assignee: 3-V Biosciences, Inc.
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Allan S. Wagman
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20180222892
    Abstract: Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.
    Type: Application
    Filed: March 30, 2018
    Publication date: August 9, 2018
    Inventors: Johan D. OSLOB, Robert S. MCDOWELL, Russell JOHNSON, Hanbiao YANG, Marc EVANCHIK, Cristiana A. ZAHARIA, Haiying CAI, Lily W. HU, Allan S. WAGMAN
  • HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS
    Publication number: 20180079746
    Abstract: Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders.
    Type: Application
    Filed: March 15, 2016
    Publication date: March 22, 2018
    Inventors: Johan D. Oslob, Robert S. McDowell, Russell Johnson, Hanbiao Yang, Marc Evanchik, Cristiana A. Zaharia, Haiying Cai, Lily W. Hu, Gregory Duke, Yamini Ohol-Gupta, Timothy Sean Heuer, Marie O'Farrell