Abstract: A system includes at least one electrode configured for transcutaneous stimulation of a pudendal nerve or surrounding perianal tissue or both. The at least one electrode is coupled to a substrate that includes a rectal portion and a buttocks support portion. The rectal portion includes a fecal blocking element. A control module is coupled to the at least one electrode, and includes a microprocessor for controlling operational parameters of the system.

Abstract: A modular vault assembly including a plurality of vault modules variable in number and including a primary vault and one or more secondary vaults. The secondary vaults are interconnected in successively adjacent relation and a leading secondary vault is connected adjacent to the primary vault. The primary vault and each of the secondary vaults respectively include a master door and a slave door having a locking mechanism disposable in a locked and unlocked orientation. The locking mechanism of the leading secondary vault is manually positioned in the unlocked orientation from an interior of said primary vault and each of said locking mechanisms of a remainder of the secondary vaults is manually positioned, successively, in the unlocked orientation from an interior of a preceding, next adjacent one of the plurality of secondary vaults. Each master and slave door includes a sensor assembly indicating the locked orientation of a corresponding locking mechanism.

Abstract: A modular vault assembly including a plurality of vault modules variable in number and including a primary vault and one or more secondary vaults. The secondary vaults are interconnected in successively adjacent relation and a leading secondary vault is connected adjacent to the primary vault. The primary vault and each of the secondary vaults respectively include a master door and a slave door having a locking mechanism disposable in a locked and unlocked orientation. The locking mechanism of the leading secondary vault is manually positioned in the unlocked orientation from an interior of said primary vault and each of said locking mechanisms of a remainder of the secondary vaults is manually positioned, successively, in the unlocked orientation from an interior of a preceding, next adjacent one of the plurality of secondary vaults. Each master and slave door includes a sensor assembly indicating the locked orientation of a corresponding locking mechanism.

Abstract: A modular vault assembly including a plurality of vault modules variable in number and including a primary vault and one or more secondary vaults. The secondary vaults are interconnected in successively adjacent relation and a leading secondary vault is connected adjacent to the primary vault. The primary vault and each of the secondary vaults respectively include a master door and a slave door having a locking mechanism disposable in a locked and unlocked orientation. The locking mechanism of the leading secondary vault is manually positioned in the unlocked orientation from an interior of said primary vault and each of said locking mechanisms of a remainder of the secondary vaults is manually positioned, successively, in the unlocked orientation from an interior of a preceding, next adjacent one of the plurality of secondary vaults. Each master and slave door includes a sensor assembly indicating the locked orientation of a corresponding locking mechanism.

Abstract: A method for detecting the absence or presence of cells of interest in a liquid sample is provided. The method comprises providing a sample suspected of containing cells of interest that contain an intracellular enzyme with a measurable activity. The sample further comprises an extracellular medium that also includes an extracellular enzyme with the measurable activity. The method further comprises the steps of treating the liquid sample with a reagent that inactivates the measurable activity in the extracellular medium but does not inactivate the measurable activity in the cells of interest, lysing the cells of interest to release the intracellular enzyme, and measuring the measurable activity. Thus, the measurable activity of the intracellular enzyme can be measured without interference from the extracellular enzyme. The invention is particularly useful for treatment of bacterially-infected blood using a detection assay based on adenylate kinase activity.

Abstract: A method for detecting the absence or presence of cells of interest in a liquid sample, wherein: (a) the sample: (i) comprises an extracellular medium containing an enzyme with a measurable activity; and (ii) is suspected of containing cells of interest that contain an enzyme with said measurable activity; and (b) the method comprises the steps of: (i) treating the liquid sample with a reagent that inactivates said measurable activity in the extracellular medium, but does not inactivate the measurable activity in said cells of interest; (ii) lysing the cells of interest to release the intracellular enzyme; and (iii) measuring said measurable activity. Thus the intracellular enzyme can be measured without interference from the extracellular enzyme. The invention is particularly useful for treatment of bacterially-infected blood using a detection assay based on adenylate kinase activity.