Patents by Inventor Marc Karel Jozef François

Marc Karel Jozef François has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220273653
    Abstract: This invention concerns pharmaceutical compositions for administration via intramuscular or subcutaneous injection, comprising micro- or nanoparticles of the NNRTI compound TMC278, suspended in an aqueous pharmaceutically acceptable carrier, and the use of such pharmaceutical compositions in the treatment and prophylaxis of HIV infection.
    Type: Application
    Filed: May 16, 2022
    Publication date: September 1, 2022
    Inventors: Lieven Elvire Colette Baert, Willy Albert Maria Carlo Dries, Laurent Bruno Schueller, Marc Karel Jozef Francois, Peter Jozef Maria Van Remoortere
  • Patent number: 11389447
    Abstract: This invention concerns pharmaceutical compositions for administration via intramuscular or subcutaneous injection, comprising micro- or nanoparticles of the NNRTI compound TMC278, suspended in an aqueous pharmaceutically acceptable carrier, and the use of such pharmaceutical compositions in the treatment and prophylaxis of HIV infection.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: July 19, 2022
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Lieven Elvire Colette Baert, Willy Albert Maria Carlo Dries, Laurent Bruno Schueller, Marc Karel Jozef Francois, Peter Jozef Maria Van Remoortere
  • Patent number: 9320707
    Abstract: The present invention is concerned with a pharmaceutical composition suitable as a depot formulation for administration via intramuscular or subcutaneous injection, comprising: (1) as an active ingredient a therapeutically effective amount of a 9-hydroxyrisperidone fatty acid ester or a salt, or a stereoisomer or a stereoisomeric mixture thereof in submicron form and (2) a pharmaceutically acceptable carrier; wherein the pharmaceutically acceptable carrier is water and the active ingredient is suspended therein: and with a process of preparing such a composition. The invention further concerns such a pharmaceutical composition for use as a medicament in the treatment of psychosis, schizophrenia, schizoaffective disorders, non-schizophrenic psychoses, behavioral disturbances associated with neurodegenerative disorders, e.g. in dementia, behavioral disturbances in mental retardation and autism, Tourette's syndrome, bipolar mania, depression, anxiety.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: April 26, 2016
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Marc Karel Jozef François, Willy Maria Albert Carlo Dries, Esther Dina Guido Basstanie
  • Publication number: 20160089369
    Abstract: This invention concerns pharmaceutical compositions for administration via intramuscular or subcutaneous injection, comprising micro- or nanoparticles of the NNRTI compound TMC278, suspended in an aqueous pharmaceutically acceptable carrier, and the use of such pharmaceutical compositions in the treatment and prophylaxis of HIV infection.
    Type: Application
    Filed: December 9, 2015
    Publication date: March 31, 2016
    Inventors: Lieven Elvire Colette Baert, Willie Albert Maria Carlo Dries, Laurent Bruno Schueller, Marc Karel Jozef Francois, Peter Jozef Maria Van Remoortere
  • Publication number: 20150010637
    Abstract: This invention concerns pharmaceutical compositions for administration via intramuscular or subcutaneous injection, comprising micro- or nanoparticles of the NNRTI compound TMC278, suspended in an aqueous pharmaceutically acceptable carrier, and the use of such pharmaceutical compositions in the treatment and prophylaxis of HIV infection.
    Type: Application
    Filed: September 23, 2014
    Publication date: January 8, 2015
    Inventors: Lieven Elvire Colette Baert, Willie Albert Maria Carlo Dries, Laurent Bruno Schueller, Marc Karel Jozef Francois, Peter Jozef Maria Van Remoortere
  • Publication number: 20120263795
    Abstract: The present invention is concerned with a pharmaceutical composition suitable as a depot formulation for administration via intramuscular or subcutaneous injection, comprising: (1) as an active ingredient a therapeutically effective amount of a 9-hydroxy-risperidone fatty acid ester or a salt, or a stereoisomer or a stereoisomeric mixture thereof in submicron form and (2) a pharmaceutically acceptable carrier; wherein the pharmaceutically acceptable carrier is water and the active ingredient is suspended therein: and with a process of preparing such a composition. The invention further concerns such a pharmaceutical composition for use as a medicament in the treatment of psychosis, schizophrenia, schizoaffective disorders, non-schizophrenic psychoses, behavioural disturbances associated with neurodegenerative disorders, e.g. in dementia, behavioural disturbances in mental retardation and autism, Tourette's syndrome, bipolar mania, depression, anxiety.
    Type: Application
    Filed: June 29, 2012
    Publication date: October 18, 2012
    Inventors: Marc Karel Jozef François, Willy Maria Albert Carlo Dries, Esther Dina Guido Basstanie
  • Publication number: 20080234291
    Abstract: The present invention concerns an oral solution comprising the MTP inhibitor mitratapide or an pharmaceutically acceptable acid addition salt thereof, a process for preparing such solutions, and their use in the treatment of MTP-related disorders such as hyperlipidemia, obesity, or type II diabetes.
    Type: Application
    Filed: January 18, 2005
    Publication date: September 25, 2008
    Inventors: Marc Karel Jozef Francois, Roger Carolus Augusta Embrechts, Willy Maria Albert Carlo Dries
  • Patent number: 6806256
    Abstract: This invention is directed to a taste masked liquid pharmaceutical composition comprising a pharmaceutically active agent and a taste masking composition. In particular, the taste masking composition comprises a taste masking effective amount of an artificial sweetener.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: October 19, 2004
    Assignee: Ortho -McNeil Pharmaceutical, Inc.
    Inventors: Stephen A. Ulrich, Karen R. Zimm, Marc Karel Jozef Francois, Willy Maria Albert Carlo Dries
  • Publication number: 20030157180
    Abstract: The present invention is concerned with a pharmaceutical composition suitable as a depot formulation for administration via intramuscular or subcutaneous injection, comprising:
    Type: Application
    Filed: March 6, 2003
    Publication date: August 21, 2003
    Inventors: Marc Karel Jozef Francois, Willy Maria Albert Carlo Dries, Esther Dina Guido Basstanie
  • Patent number: 6555544
    Abstract: The present invention is concerned with a pharmaceutical composition suitable as a depot formulation for administration via intramuscular or subcutaneous injection, comprising: (1) as an active ingredient a therapeutically effective amount of a 9-hydroxy-risperidone fatty acid ester or a salt, or a stereoisomer or a stereoisomeric mixture thereof in submicron form and (2) a pharmaceutically acceptable carrier; wherein the pharmaceutically acceptable carrier is water and the active ingredient is suspended therein: and with a process of preparing such a composition. The invention further concerns such a pharmaceutical composition for use as a medicament in the treatment of psychosis, schizophrenia, schizoaffective disorders, non-schizophrenic psychoses, behavioural disturbances associated with neurodegenerative disorders, e.g. in dementia, behavioural disturbances in mental retardation and autism, Tourette's syndrome, bipolar mania, depression, anxiety.
    Type: Grant
    Filed: May 2, 2000
    Date of Patent: April 29, 2003
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Marc Karel Jozef François, Willy Maria Albert Carlo Dries, Esther Dina Guido Basstanie
  • Publication number: 20030064998
    Abstract: The present invention is concerned with a pharmaceutical composition suitable as a depot formulation for administration via intramuscular or subcutaneous injection, comprising:
    Type: Application
    Filed: May 2, 2000
    Publication date: April 3, 2003
    Inventors: MARC KAREL JOZEF FRANCOIS, WILLY MARIA ALBERT CARLO DRIES, ESTHER DINA GUIDO BASSTANIE
  • Publication number: 20030032600
    Abstract: This invention is directed to a taste masked liquid pharmaceutical composition comprising a pharmaceutically active agent and a taste masking composition. In particular, the taste masking composition comprises a taste masking effective amount of an artificial sweetener.
    Type: Application
    Filed: February 26, 2002
    Publication date: February 13, 2003
    Inventors: Stephen A. Ulrich, Karen R. Zimm, Marc Karel Jozef Francois, Willy Maria Albert Carlo Dries
  • Patent number: 5854246
    Abstract: The invention concerns stable emulsions comprising ketoconazole having a pH in the range from 6 to 8, characterized in that the emulsions lack sodium sulfite as an antioxidant; process of preparing said emulsions.
    Type: Grant
    Filed: February 24, 1997
    Date of Patent: December 29, 1998
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Marc Karel Jozef Francois, Eric Carolus Leonarda Snoeckx
  • Patent number: RE39181
    Abstract: The present invention is concerned with physicochemically stable aqueous solutions of risperidone for oral and parenteral administration; processes for preparing such formulations.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: July 11, 2006
    Inventors: Marc Karel Jozef François, Willy Maria Albert Carlo Dries