Abstract: The present invention is directed to a personal composition comprising a) a strobilurin; b) a 2-pyridinol-N-oxide material wherein the ratio of a:b is from about 10:1 to about 1:20; wherein there is a synergistic anti-inflammatory/cellular stress activity.

Abstract: The disclosure provides methods of reprogramming polyclonal T cells to maintain long-term persistence. The disclosure further provides methods of treatment, such as adoptive T cell transfer therapies, that harness Tscms for development of tumor-reactive T cells. In some embodiments, the disclosure provides methods and compositions for positive modulation of the Tscm-producing phenotype, e.g., positive modulation of TCF7 expression. Positive modulation of TCF7 expression allows for maintenance of an increased T number of stem-like T cells capable of both self-renewal and generation of differentiated, cytolytic progeny.

Abstract: A forced air hand dryer includes a communication device that communicatively couples to a computing entity in provide data regarding the use of the hand dryer, and/or to set an operating configuration of the hand dryer.

Abstract: A forced air hand dryer includes a communication device that communicatively couples to a computing entity in provide data regarding the use of the hand dryer, and/or to set an operating configuration of the hand dryer.

Abstract: A method is disclosed of providing real time interactive participation during a game by a plurality of users through a plurality of game clients, respectively, wherein progress of the game is defined by a plurality of plays, the method is implemented by a system in which one or more nodes on a network are configured to communicate with a plurality of game clients and a central system, each node including one or more servers, the one or more servers are programmed to execute the method, the method comprising: requesting, by a game client, to communicate with the central system via a node in a cluster; searching for a node in the cluster with available bandwidth to communicate with the game client; initiating a direct connection between the client and the node with available bandwidth for communication; assigning the node the game client to enable direct communication relating to the game between the game client and the node; receiving, via the game client, a selection from the user of a play in the game, the s

Abstract: A method is disclosed of providing real time interactive participation during a game by a plurality of users through a plurality of game clients, respectively, wherein progress of the game is defined by a plurality of plays, the method is implemented by a system in which one or more nodes on a network are configured to communicate with a plurality of game clients and a central system, each node including one or more servers, the one or more servers are programmed to execute the method, the method comprising: requesting, by a game client, to communicate with the central system via a node in a cluster; searching for a node in the cluster with available bandwidth to communicate with the game client; initiating a direct connection between the client and the node with available bandwidth for communication; assigning the node the game client to enable direct communication relating to the game between the game client and the node; receiving, via the game client, a selection from the user of a play in the game, the s

Abstract: A forced air hand dryer includes a communication device that communicatively couples to a computing entity in provide data regarding the use of the hand dryer, and/or to set an operating configuration of the hand dryer.

Abstract: The present invention provides conjugates between Granulocyte Colony Stimulating Factor and PEG moieties. The conjugates are linked via an intact glycosyl linking group that is interposed between and covalently attached to the peptide and the modifying group. The conjugates are formed from both glycosylated and unglycosylated peptides by the action of a glycosyltransferase. The glycosyltransferase ligates a modified sugar moiety onto either an amino acid or glycosyl residue on the peptide. Also provided are pharmaceutical formulations including the conjugates. Methods for preparing the conjugates are also within the scope of the invention.

Abstract: The present invention provides enhanced methods of producing soluble, active eukaryotic glycosyltransferases in prokaryotic microorganisms that have an oxidizing environment.