Patents by Inventor Marc Tjwa

Marc Tjwa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8003096
    Abstract: Described are methods of modulating stem/progenitor cell recruitment involving molecules that agonize the formation of plasmin stimulating the recruitment of stem/progenitor cells, including hematopoietic and endothelial precursor cells. Conversely, antagonists of plasmin can inhibit recruitment of the stem cells. In addition, the identification of the uPA receptor (uPAR) as a retention signal for stem cells in their niche suggests a novel method for increased engraftment and isolation of multipotent stem cells.
    Type: Grant
    Filed: March 28, 2006
    Date of Patent: August 23, 2011
    Assignees: Vlaams Interuniversitair Instituut voor Biotechnologie VZW, Life Sciences Research Partners VZW
    Inventors: Peter Carmeliet, Marc Tjwa
  • Publication number: 20100178297
    Abstract: Described are methods of modulating stem/progenitor cell recruitment involving molecules that agonize the formation of plasmin stimulating the recruitment of stem/progenitor cells, including hematopoietic and endothelial precursor cells. Conversely, antagonists of plasmin can inhibit recruitment of the stem cells. In addition, the identification of the uPA receptor (uPAR) as a retention signal for stem cells in their niche suggests a novel method for increased engraftment and isolation of multipotent stem cells.
    Type: Application
    Filed: July 1, 2009
    Publication date: July 15, 2010
    Inventors: Peter Carmeliet, Marc Tjwa
  • Publication number: 20060210532
    Abstract: Described are methods of modulating stem/progenitor cell recruitment involving molecules that agonize the formation of plasmin stimulating the recruitment of stem/progenitor cells, including hematopoietic and endothelial precursor cells. Conversely, antagonists of plasmin can inhibit recruitment of the stem cells. In addition, the identification of the uPA receptor (uPAR) as a retention signal for stem cells in their niche suggests a novel method for increased engraftment and isolation of multipotent stem cells.
    Type: Application
    Filed: March 28, 2006
    Publication date: September 21, 2006
    Applicants: Vlaams Interuniversitair Instituut Voor Biotechnologie VZW, D. Collen Research Foundation vzw
    Inventors: Peter Carmeliet, Marc Tjwa