Abstract: Accessories of a medical device, such as a defibrillator, are described. The accessories reduce delays in treating or monitoring a patient by increasing the efficiency of using, and the ease of use of, the medical device. An adjustable kickstand is movable between a collapsed and extended position to recline the medical device. In the reclined position, a display of the medical device can be more easily viewed by the user. Storage bags can be coupled to the medical device to efficiently store accessories for use with the medical device. The stored accessories can be coupled to the medical device while the accessories are stored within the storage bags. A port guard can protect and shield a connection between a cable and a port of the medical device to prevent the cable (e.g., an ECG cable) from being disconnected from the port of the medical device.

Abstract: A method for generating optimal arch forms for a patient's dental arch is presented. The method comprises: receiving first positional digital data for one or more teeth from a reconstructed 3D digital volume of the patient dental arch; (b) generating second positional digital data for the one or more teeth according to a desired dental arch form for the patient; (c) calculating a first displacement data for one or more teeth according to the first positional and second positional digital data; (d) detecting teeth collision values based on the first displacement data; (e) calculating a second displacement data for one or more teeth based on the detected teeth collision values; and (f) reporting a combination of the first displacement data and second displacement data for repositioning one tooth or more teeth of the dental arch.

Abstract: An apparatus for acquiring intraoral images of a subject has an OCT imaging apparatus having an OCT light source, a scanner that conveys OCT light toward the subject and returned from the subject, and an interferometer having a reference arm and a sample arm. A reflectance imaging apparatus has a visible light source directed toward the subject and an image sensor that forms a reflectance image from returned light. Processing and control logic are configured to process and combine the returned reflectance image to the OCT measured data. A display shows the combined reflectance image and OCT measured data.

Abstract: Systems and processes for iteratively training a network training module are described herein. In various embodiments, the process includes: (1) retrieving bulk data comprising a plurality of a data types, (2) transforming the bulk data according to preconfigured classification values to generate network information data sets; (3) training a raw training module by iteratively processing each of the network information data sets through a raw training module to generate respective output classification values; (4) updating one or more classification values based on a comparison of the respective output classification values; (5) processing an input network information data set with a trained training module to generate a specific network constituent; and (6) modifying a display based on the plurality of classification values.

Abstract: The current invention reports a method for purifying an antibody by reducing the content of a host cell protein. The method employs a wash step with a low conductivity aqueous solution in an affinity chromatography.

Abstract: The present disclosure provides purification platforms comprising a depth filter step and/or a hydrophobic interaction chromatography (HIC) step and/or a MM-HIC/IEX chromatography step, and are useful for providing a method of reducing a hydrolytic enzyme activity rate of a composition obtained from said purification platforms. Also disclosed herein are methods of using the purification platforms described herein and compositions obtained therefrom, such as pharmaceutical compositions.

Abstract: The present invention provides methods for producing disulfide oxidoreductase A (DsbA) and disulfide oxidoreductase C (DsbC) polypeptides at very high levels of purity. Also provided are ultrapure DsbA and DsbC and methods of using same, e.g., for use in immunoassays to show removal of DsbA and DsbC from biologics produced in bacteria.

Abstract: Provided herein are methods of purifying anti-c-met antibodies, compositions, and pharmaceutical formulations comprising purified anti-c-met antibodies, and methods of using the same.

Abstract: The present invention provides methods for producing disulfide oxidoreductase A (DsbA) and disulfide oxidoreductase C (DsbC) polypeptides at very high levels of purity. Also provided are ultrapure DsbA and DsbC and methods of using same, e.g., for use in immunoassays to show removal of DsbA and DsbC from biologics produced in bacteria.

Abstract: The present invention provides methods for producing disulfide oxidoreductase A (DsbA) and disulfide oxidoreductase C (DsbC) polypeptides at very high levels of purity. Also provided are ultrapure DsbA and DsbC and methods of using same, e.g., for use in immunoassays to show removal of DsbA and DsbC from biologics produced in bacteria.

Abstract: The current invention reports a method for purifying an antibody by reducing the content of a host cell protein. The method employs a wash step with a low conductivity aqueous solution in an affinity chromatography.

Abstract: The present invention provides methods for producing disulfide oxidoreductase A (DsbA) and disulfide oxidoreductase C (DsbC) polypeptides at very high levels of purity. Also provided are ultrapure DsbA and DsbC and methods of using same, e.g., for use in immunoassays to show removal of DsbA and DsbC from biologics produced in bacteria.

Abstract: Provided herein are methods of purifying anti-c-met antibodies, compositions and pharmaceutical formulations comprising purified anti-c-met antibodies, and methods of using the same.