Abstract: Disclosed is a method of assembling a chromatography column including the steps of providing a cylindrical core element, winding an innermost layer of uniformly spaced fibers helically about the core element, winding a plurality of concentric annular layers of uniformly spaced fibers about the innermost layer so that the fibers of each layer are helically wound about the most inwardly adjacent layer in reverse hand orientation relative to the next inwardly adjacent layer, enveloping the outermost layer of fibers in a column housing, and coating the fibers with stationary phase material.

Abstract: Disclosed is a chromatographic column having an elongated housing, an elongated central core element, a plurality of annular, concentric would fiber layers, so as to form a plurality of uniform fluid passageway, though the housing, and a coating of stationary phase material on the passageways.