Patents by Inventor Marcel MIAMPAMBA

Marcel MIAMPAMBA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11771774
    Abstract: Described herein are methods and compositions for nerve delivery molecules that carry imaging cargo or therapeutic cargo to the neurons or nerves.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: October 3, 2023
    Assignee: Avelas Acquisition Corporation
    Inventors: Jesus Gonzalez, Junjie Liu, Marcel Miampamba
  • Publication number: 20220347306
    Abstract: Described herein are methods and compositions for the targeted delivery of selective delivery molecule therapeutic agents and imaging agents.
    Type: Application
    Filed: April 16, 2019
    Publication date: November 3, 2022
    Inventors: Jesus E. GONZALEZ, Junjie LIU, Marcel MIAMPAMBA, Ning ZOU, Andrew GALE
  • Publication number: 20210268120
    Abstract: Described herein are methods and compositions for nerve delivery molecules that carry imaging cargo or therapeutic cargo to the neurons or nerves.
    Type: Application
    Filed: February 17, 2021
    Publication date: September 2, 2021
    Inventors: Jesus Gonzalez, Junjie Liu, Marcel Miampamba
  • Patent number: 10994017
    Abstract: Described herein are methods and compositions for nerve delivery molecules that carry imaging cargo or therapeutic cargo to the neurons or nerves.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: May 4, 2021
    Assignee: Avelas Biosciences, Inc.
    Inventors: Jesus Gonzalez, Junjie Liu, Marcel Miampamba
  • Publication number: 20210079039
    Abstract: Described herein are methods and compositions for the targeted delivery of therapeutic agents and imaging agents.
    Type: Application
    Filed: April 16, 2019
    Publication date: March 18, 2021
    Inventors: Jesus E. GONZALEZ, Junjie LIU, Marcel MIAMPAMBA, Giuseppe DELLO IACANO, Ning ZOU, Andrew GALE
  • Publication number: 20200376013
    Abstract: Described herein are methods and compositions for intracellular delivery of therapeutic molecules. Disclosed herein are selective delivery conjugate comprising a targeting ligand conjugated to a selective delivery molecule (a) an acidic sequence (portion of A) which is effective to inhibit or prevent the uptake into cells or tissue retention, (b) a molecular transport or retention sequence (portion of B), and (c) a linker between portion of A and portion of B, and (d) at least one cargo moiety. Also, described are selective delivery molecules comprising a second linker comprising an intracellular cleavage site and optionally a self-immolative cleavage site.
    Type: Application
    Filed: August 7, 2020
    Publication date: December 3, 2020
    Inventors: Jesus GONZALEZ, Junjie LIU, Marcel MIAMPAMBA
  • Publication number: 20200061200
    Abstract: Described herein are methods and compositions for nerve delivery molecules that carry imaging cargo or therapeutic cargo to the neurons or nerves.
    Type: Application
    Filed: December 1, 2017
    Publication date: February 27, 2020
    Inventors: Jesus GONZALEZ, Junjie LIU, Marcel MIAMPAMBA
  • Publication number: 20190374560
    Abstract: Described herein are methods and compositions for intracellular delivery of therapeutic molecules. Disclosed herein are selective delivery conjugate comprising a targeting ligand conjugated to a selective delivery molecule (a) an acidic sequence (portion of A) which is effective to inhibit or prevent the uptake into cells or tissue retention, (b) a molecular transport or retention sequence (portion of B), and (c) a linker between portion of A and portion of B, and (d) at least one cargo moiety. Also, described are selective delivery molecules comprising a second linker comprising an intracellular cleavage site and optionally a self-immolative cleavage site.
    Type: Application
    Filed: June 24, 2019
    Publication date: December 12, 2019
    Inventors: Jesus GONZALEZ, Junjie LIU, Marcel MIAMPAMBA
  • Publication number: 20160082119
    Abstract: Described herein are methods and compositions for intracellular delivery of therapeutic molecules. Disclosed herein are selective delivery conjugate comprising a targeting ligand conjugated to a selective delivery molecule (a) an acidic sequence (portion of A) which is effective to inhibit or prevent the uptake into cells or tissue retention, (b) a molecular transport or retention sequence (portion of B), and (c) a linker between portion of A and portion of B, and (d) at least one cargo moiety. Also, described are selective delivery molecules comprising a second linker comprising an intracellular cleavage site and optionally a self-immolative cleavage site.
    Type: Application
    Filed: April 22, 2014
    Publication date: March 24, 2016
    Inventors: Jesus GONZALEZ, Junjie LIU, Marcel MIAMPAMBA