Abstract: An electrode system is disclosed for measuring a concentration or presence of an analyte under in-vivo conditions, where the electrode system includes at least one electrode with immobilized enzyme molecules and an improved diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules. The diffusion barrier includes a hydrophilic polyurethane or a block copolymer having at least one hydrophilic block and at least one hydrophobic block. The electrode system also can include a spacer membrane that includes a hydrophilic copolymer of acrylic and/or methacrylic monomers.

Abstract: A medical device and method of making the medical device are disclosed. The medical device includes a sensor having an interconnect. The interconnect has a first conductive layer, an insulation layer, and a second conductive layer separated from the first conductive layer by the insulation layer. An electrical contact is provided that is electrically connected to the second conductive layer and is contactable from the side of the interconnect that opposes the second conductive layer. The electrical contact is provided free of micro-vias. The medical device also includes an electronics assembly having an electrical connector, the electronics assembly configured to mate with the interconnect to establish an electrical connection between the electrical connector and the first conductive layer via the electrical contact.

Abstract: An ultrasonic doppler motion sensor device includes a transmitter (10, 12) for emitting a continuous ultrasonic transmission signal in a detection space, an ultrasonic receiver (20, 22) for detecting the ultrasonic transmission signal reflected by the detection object as a receive signal, and a mixer and detector (14, 18) for mixing the ultrasonic transmission signal or a signal derived therefrom with the receive signal and/or for demodulating the receive signal and for generating a motion detection signal therefrom, wherein the mixer and detector are assigned a system (14) for the adjustable generation of a phase shift greater than 0° between a phase of the ultrasonic transmission signal and a periodic impulse signal at the mixer or detector for scanning and mixing the receive signal.

Abstract: A medical device and method of making the medical device are disclosed. The medical device includes a sensor having an interconnect. The interconnect has a first conductive layer, an insulation layer, and a second conductive layer separated from the first conductive layer by the insulation layer. An electrical contact is provided that is electrically connected to the second conductive layer and is contactable from the side of the interconnect that opposes the second conductive layer. The electrical contact is provided free of micro-vias. The medical device also includes an electronics assembly having an electrical connector, the electronics assembly configured to mate with the interconnect to establish an electrical connection between the electrical connector and the first conductive layer via the electrical contact.

Abstract: Electrode systems are disclosed for measuring the concentration of an analyte under in vivo conditions, where the systems includes an electrode with immobilized enzyme molecules and an improved diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules. Methods of making and using the system also are disclosed.

Abstract: An ultrasonic doppler motion sensor device comprising transmitter means (10, 12) for emitting a continuous ultrasonic transmission signal in a detection space, ultrasonic receiver means (20, 22) for detecting the ultrasonic transmission signal reflected by the detection object as a receive signal, and mixer and detector means (14, 18) for mixing the ultrasonic transmission signal or a signal derived therefrom with the receive signal and/or for demodulating the receive signal and for generating a motion detection signal therefrom, wherein the mixer and detector means are assigned means (14) for the adjustable generation of a phase shift greater than 0° between a phase of the ultrasonic transmission signal and a periodic impulse signal at the mixer or detector means for scanning and mixing the receive signal.

Abstract: A method for the quantitative determination of an analyte in a sample is provided comprising: (a) providing an analyte-specific substance which is able to undergo a reaction which generates a detectable signal when it is contacted with an analyte; (b) providing at least two calibration graphs which have been generated by reacting in each case the same analyte-specific substance with different amounts of in each case the same test analyte for in each case a predetermined reaction time; (c) contacting the analyte-specific substance with a sample which contains the analyte to be detected; (d) measuring the signal at a first predetermined reaction time for which a first calibration graph according to (b) is provided; (c) checking whether the signal measured according to (d) enables a quantitative determination of the analyte with a desired accuracy; (f) (i) quantitatively determining the analyte on the basis of the signal measured according to (d) if the desired accuracy is reached, or (ii) measuring the signal a

Abstract: An electrode system is disclosed for measuring a concentration or presence of an analyte under in-vivo conditions, where the electrode system includes at least one electrode with immobilized enzyme molecules and an improved diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules. The diffusion barrier includes a hydrophilic polyurethane or a block copolymer having at least one hydrophilic block and at least one hydrophobic block. The electrode system also can include a spacer membrane that includes a hydrophilic copolymer of acrylic and/or methacrylic monomers.

Abstract: A method for the quantitative determination of an analyte in a sample is provided comprising: (a) providing an analyte-specific substance which is able to undergo a reaction which generates a detectable signal when it is contacted with an analyte; (b) providing at least two calibration graphs which have been generated by reacting in each case the same analyte-specific substance with different amounts of in each case the same test analyte for in each case a predetermined reaction time; (c) contacting the analyte-specific substance with a sample which contains the analyte to be detected; (d) measuring the signal at a first predetermined reaction time for which a first calibration graph according to (b) is provided; (c) checking whether the signal measured according to (d) enables a quantitative determination of the analyte with a desired accuracy; (f) (i) quantitatively determining the analyte on the basis of the signal measured according to (d) if the desired accuracy is reached, or (ii) measuring the signal a

Abstract: Electrode systems are disclosed for measuring the concentration of an analyte under in vivo conditions, where the systems includes an electrode with immobilized enzyme molecules and an improved diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules. Methods of making and using the system also are disclosed.

Abstract: A method for the quantitative determination of an analyte in a sample is provided comprising: (a) providing an analyte-specific substance which is able to undergo a reaction which generates a detectable signal when it is contacted with an analyte; (b) providing at least two calibration graphs which have been generated by reacting in each case the same analyte-specific substance with different amounts of in each case the same test analyte for in each case a predetermined reaction time; (c) contacting the analyte-specific substance with a sample which contains the analyte to be detected; (d) measuring the signal at a first predetermined reaction time for which a first calibration graph according to (b) is provided; (e) checking whether the signal measured according to (d) enables quantitative determination of the analyte with a desired accuracy; (f) (i) quantitatively determining the analyte on the basis of the signal measured according to (d) if the desired accuracy is reached, or (ii) measuring the signal at