Patents by Inventor Marco Santamaria

Marco Santamaria has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230041686
    Abstract: A method for producing ACE Inhibitor peptides from a protein source or plasma is disclosed. The method utilizes proteolysis by intestinal, blood-circulating, or membrane-bound proteases. The initial synthesis step could require obtaining a protein source either from a human or animal. A protease is added to either a given plasma protein or plasma and incubated. Following incubation, the protease activity must be quenched using a protease inhibitor to inactivate the protease. After incubation with protease inhibitor, the solution will contain a mixture of bioactive ACE inhibitory peptides and inert peptides. This mixture may be purified to select for the ACE inhibitory peptides through centrifugation. The mixture may also be sterilized to remove any microbial contaminants. The ACE inhibitory peptides can be mixed with protein powders, incorporated into baked good and put into other food products to provide food products with the added benefit of lowering blood pressure.
    Type: Application
    Filed: April 5, 2022
    Publication date: February 9, 2023
    Applicant: St. Marie Intellectual Property Holdings LLC
    Inventor: Marco Santamaria
  • Patent number: 11324810
    Abstract: A method for producing ACE Inhibitor peptides from a protein source or plasma is disclosed. The method utilizes proteolysis by intestinal, blood-circulating, or membrane-bound proteases. The initial synthesis step could require obtaining a protein source either from a human or animal. A protease is added to either a given plasma protein or plasma and incubated. Following incubation, the protease activity must be quenched using a protease inhibitor to inactivate the protease. After incubation with protease inhibitor, the solution will contain a mixture of bioactive ACE inhibitory peptides and inert peptides. This mixture may be purified to select for the ACE inhibitory peptides through centrifugation. The mixture may also be sterilized to remove any microbial contaminants. The ACE inhibitory peptides can be mixed with protein powders, incorporated into baked good and put into other food products to provide food products with the added benefit of lowering blood pressure.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: May 10, 2022
    Assignee: St. Marie Intellectual Property Holdings, LLC
    Inventor: Marco Santamaria
  • Publication number: 20190262436
    Abstract: A method for producing ACE Inhibitor peptides from a protein source or plasma is disclosed. The method utilizes proteolysis by intestinal, blood-circulating, or membrane-bound proteases. The initial synthesis step could require obtaining a protein source either from a human or animal. A protease is added to either a given plasma protein or plasma and incubated. Following incubation, the protease activity must be quenched using a protease inhibitor to inactivate the protease. After incubation with protease inhibitor, the solution will contain a mixture of bioactive ACE inhibitory peptides and inert peptides. This mixture may be purified to select for the ACE inhibitory peptides through centrifugation. The mixture may also be sterilized to remove any microbial contaminants. The ACE inhibitory peptides can be mixed with protein powders, incorporated into baked good and put into other food products to provide food products with the added benefit of lowering blood pressure.
    Type: Application
    Filed: December 17, 2018
    Publication date: August 29, 2019
    Inventor: Marco Santamaria
  • Patent number: 7240030
    Abstract: In the present invention, a system and method is described for allocating portfolio assets in an emerging market, where the portfolio initially includes substantially all fixed income securities or substantially all equities. Specifically, a yield spread is periodically determining between a first fixed income instrument and a second fixed income instrument. A mean spread is determined based on the determined yield spread over a selected period of time. A band above and below the mean spread is defined over the selected period of time, where the band has an upper limit above the mean spread and a lower limit below the mean spread. Fixed income securities, in the investment portfolio, are switched for equities when a current determined yield spread exceeds the upper limit of the band. Similarly, equities, in the portfolio, are switched for fixed income securities when the current determined yield spread falls below the lower limit of the band.
    Type: Grant
    Filed: September 5, 2001
    Date of Patent: July 3, 2007
    Assignee: American International Group, Inc.
    Inventors: Deborah A. Velez, Marco Santamaria, Gawaine Lewis
  • Publication number: 20030004849
    Abstract: In the present invention, a system and method is described for allocating portfolio assets in an emerging market, where the portfolio initially includes substantially all fixed income securities or substantially all equities. Specifically, a yield spread is periodically determining between a first fixed income instrument and a second fixed income instrument. A mean spread is determined based on the determined yield spread over a selected period of time. A band above and below the mean spread is defined over the selected period of time, where the band has an upper limit above the mean spread and a lower limit below the mean spread. Fixed income securities, in the investment portfolio, are switched for equities when a current determined yield spread exceeds the upper limit of the band. Similarly, equities, in the portfolio, are switched for fixed income securities when the current determined yield spread falls below the lower limit of the band.
    Type: Application
    Filed: September 5, 2001
    Publication date: January 2, 2003
    Inventors: Deborah Velez, MARCO SANTAMARIA, GAWAINE LEWIS