Abstract: A method for forming peptide-coated nanoparticles. The nanoparticles are polylactic co-glycol polymer (PLGA). The coatings are self-assembled layers selected from RGDFFF (SEQ ID NO: 1); NGRFFF (SEQ ID NO: 2), EKHFFF (SEQ ID NO: 3) or TPP-KFF. A cargo molecule, such as a dye or a therapeutic may be bound to the nanoparticle.

Abstract: A method of generating music contents from input music contents that includes development of models of music composition generation on the basis of business rules and composition rules. In parallel, sounds are prepared, which may be saved in the sound repository. Then, models in the form of source code are sent to a melody generator. Firstly, the generator is set with specific parameters using a controller conforming to MIDI standards and supplemented with composition characteristics read from the user preference database. Next, the contents are sent to automatic generation based on artificial intelligence algorithms and the digital score of the composition with the desired characteristics is generated. Sound tracks of individual instruments are rendered and the rendered tracks are mixed into the final music record. Next, the composition and its record are verified by the critic module using algorithms based on neural networks.

Abstract: A cylinder head compression sensor gasket assembly includes a gasket body having a sealing portion configured to be clamped between an engine block and a cylinder head. The sealing portion has a plurality of through openings configured to register with separate cylinder bore in the engine block wherein the sealing portion establishes a gas-tight seal about the through passages. A plurality of pressure sensor assemblies are attached in sealed engagement with the gasket body with at least one of the pressure sensor assemblies being configured to sense pressure within a separate one of the through openings. An electrical connector is supported on the gasket body radially outwardly from the sealing portion. The electrical connector is configured in electrical communication with each of the pressure sensor assemblies. Accordingly, the electrical connector is accessible without having to disassemble the gasket body from being clamped between the cylinder head and the engine block.

Abstract: In an integrated glow plug and pressure sensor having a passage leading to the pressure sensor, a porous filter is inserted in the passage. The porous filter provides a four-fold improvement in pressure measurement by (1) acting as a trap for combustion deposits, (2) burning combustion deposits when the glow plug heater is on, (3) acting as a heat shield for reducing thermal shock error of the pressure sensor, and (4) damping acoustic high frequency ringing associated with the pressure passage.

Abstract: Fuel injectors (10) for internal combustion engines are modified and equipped with fiber optic fuel pressure sensors (12) and fiber optic combustion pressure sensors (14). The combustion pressure sensors (14) are located in separate channels (26) formed in the fuel injectors with the lower portion (22) of the channels leading to the combustion chambers. Above the combustion pressure sensors (14) are fiber optic leads (24). In the preferred embodiments the sensors (46) are equipped with diaphragms (40) of novel shape (48) and employ multiple pairs of fibers (86, 88), temperature sensitive components (72, 74, 126) and novel compensation and status monitoring circuits (FIGS. 6, 9, 10, 14, 15, 18).

Abstract: A cup shaped diaphragm having varying thicknesses reduces stress on the diaphragm and increases reliability of a fiber optic diaphragm sensor. The hermetic seal between the optical fiber and the ferrule body is removed from proximity of the diaphragm and is located near the opposite end of the ferrule. The effects on the ferrule of overpressure on the diaphragm are controlled by angling a portion of the ferrule tip adjacent the diaphragm. A method of sealing and locating the optical fiber to the ferrule of the sensor is described.