Patents by Inventor Maren Watkins
Maren Watkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140350218Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: ApplicationFiled: April 15, 2014Publication date: November 27, 2014Applicant: THE UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: MAREN WATKINS, BALDOMERO M. OLIVERA, DAVID R. HILLYARD, J. MICHAEL MCINTOSH
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Patent number: 8735541Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: GrantFiled: June 6, 2013Date of Patent: May 27, 2014Assignee: The University of Utah Research FoundationInventors: Maren Watkins, Baldomero M. Olivera, David R. Hillyard, J. Michael McIntosh
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Publication number: 20130338338Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: ApplicationFiled: June 6, 2013Publication date: December 19, 2013Applicants: COGNETIX, INC., THE UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: Maren WATKINS, Baldomero M. OLIVERA, David R. HILLYARD, J. Michael McIntosh, Robert M. JONES
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Patent number: 8487075Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: GrantFiled: February 7, 2012Date of Patent: July 16, 2013Assignee: The University of Utah Research FoundationInventors: Maren Watkins, Baldomero M. Olivera, David R. Hillyard, J. Michael McIntosh, Robert M. Jones
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Publication number: 20120149869Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: ApplicationFiled: February 7, 2012Publication date: June 14, 2012Applicants: COGNETIX, INC., THE UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: Maren WATKINS, Baldomero M. OLIVERA, David R. HILLYARD, J. Michael MCINTOSH, Robert M. JONES
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Patent number: 8110549Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: GrantFiled: March 8, 2011Date of Patent: February 7, 2012Assignee: University of Utah Research FoundationInventors: Maren Watkins, Baldomero M. Olivera, David R. Hillyard, J. Michael McIntosh, Robert M. Jones
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Publication number: 20110166322Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: ApplicationFiled: March 8, 2011Publication date: July 7, 2011Applicants: THE UNIVERSITY OF UTAH RESEARCH FOUNDATION, COGNETIX, INC.Inventors: Maren WATKINS, Baldomero M. OLIVERA, David R. HILLYARD, J. Michael McINTOSH, Robert M. JONES
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Patent number: 7902153Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: GrantFiled: February 17, 2010Date of Patent: March 8, 2011Assignee: University of Utah Research FoundationInventors: Maren Watkins, Baldomero M. Olivera, David R. Hillyard, J. Michael McIntosh, Robert M. Jones
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Publication number: 20100145011Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: ApplicationFiled: February 17, 2010Publication date: June 10, 2010Applicants: THE UNIVERSITY OF UTAH RESEARCH FOUNDATION, COGNETIX, INC.Inventors: Maren WATKINS, Baldomero M. OLIVERA, David R. HILLYARD, J. Michael MCINTOSH, Robert M. JONES
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Patent number: 7666840Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: GrantFiled: October 9, 2007Date of Patent: February 23, 2010Assignees: The University of Utah Research Foundation, Cognetix, Inc.Inventors: Maren Watkins, Baldomero M. Olivera, David R. Hillyard, J. Michael McIntosh, Robert M. Jones
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Publication number: 20080274976Abstract: The present invention is directed to kappaM (?M) conopeptide RIIIK and its use for blocking the flow of potassium ions through voltage-gated potassium channels. The ?M conopeptides include unglycosylated and O-glycosylated peptides.Type: ApplicationFiled: February 11, 2008Publication date: November 6, 2008Applicants: UNIVERSITY OF UTAH RESEARCH FOUNDATION, MAX-PLANCK-GESELLSCHAFT zur FORDERUNG der WISSENSCHAFTEN e.V.Inventors: Baldomero OLIVERA, Maren WATKINS, Heinrich TERLAU, Michael FERBER
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Publication number: 20080081901Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: ApplicationFiled: October 9, 2007Publication date: April 3, 2008Applicants: THE UNIVERSITY OF UTAH RESEARCH FOUNDATION, COGNETIX, INC.Inventors: Maren WATKINS, Baldomero OLIVERA, David HILLYARD, J. MCINTOSH, Robert JONES
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Patent number: 7279549Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.Type: GrantFiled: July 21, 2004Date of Patent: October 9, 2007Assignees: The University of Utah Research Foundation, Cognetix, Inc.Inventors: Maren Watkins, Baldomero M. Olivera, David R. Hillyard, J. Michael McIntosh, Robert M. Jones
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Publication number: 20060247173Abstract: The invention relates to relatively short peptides (termed ?-conotoxins herein), about 10-25 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds. The ?-conotoxins, as described herein, are useful for as neuromuscular blocking agents, such as muscle relaxants.Type: ApplicationFiled: July 7, 2006Publication date: November 2, 2006Applicants: The University of Utah Research Foundation, Cognetix, Inc.Inventors: Baldomero Olivera, Richard Layer, Maren Watkins, David Hillyard, J. McIntosh, Robert Schoenfeld, Jacob Nielsen, Robert Jones
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Publication number: 20060241046Abstract: The invention relates to linear y-carboxyglutamate rich conotoxins, derivatives or pharmaceutically acceptable salts thereof, and uses thereof, including the treatment of neurologic and psychiatric disorders, such as anticonvulsant agents, as neuroprotective agents or for the management of pain. The invention further relates to nucleic acid sequences encoding the conopeptides and encoding propeptides, as well as the propeptides.Type: ApplicationFiled: June 29, 2006Publication date: October 26, 2006Applicants: University of Utah Research Foundation, Cognetix, Inc.Inventors: Baldomero Olivera, J. McIntosh, James Garrett, Craig Walker, Maren Watkins, Robert Jones
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Publication number: 20060223984Abstract: This invention relates to relatively short peptides about 25-40 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogs to the naturally available peptides, and which include three cyclizing disulfide linkages and one or more ?carboxyglutamate residues.Type: ApplicationFiled: August 26, 2003Publication date: October 5, 2006Applicants: Cognetix Inc., University of Utah Research FoundationInventors: Michael Fainzilber, Karel Kits, Alma Burlingame, Baldomero Olivera, Craig Walker, Maren Watkins, Reshma Shetty, Lourdes Cruz, Julita Imperial, Clark Colledge
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Patent number: 7115708Abstract: The present invention is directed to ?-superfamily conotoxin peptides, derivatives or pharmaceutically acceptable salts thereof. The present invention is further directed to the use of this peptide, derivatives thereof and pharmaceutically acceptable salts thereof for the treatment of disorders associated with voltage-gated ion channels, ligand gated channels and other receptors. The invention is further directed to nucleic acid sequences encoding the ?-superfamily conotoxin peptides and encoding ?-superfamily conotoxin propeptides, as well as the ?-superfamily conotoxin propeptides.Type: GrantFiled: August 8, 2005Date of Patent: October 3, 2006Assignees: University of Utah Research Foundation, Cognetix, Inc.Inventors: Robert M. Jones, Baldomero M. Olivera, Maren Watkins, James E. Garrett
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Publication number: 20060172948Abstract: The invention relates to ?-carboxyglutamate containing conopeptides, derivatives or pharmaceutically acceptable salts thereof, and uses thereof, including the treatment of neurologic and psychiatric disorders, such as anticonvulsant agents, as neuroprotective agents or for the management of pain. The invention further relates to nucleic acid sequences encoding the conopeptides and encoding propeptides, as well as the propeptides.Type: ApplicationFiled: March 22, 2006Publication date: August 3, 2006Applicants: University of Utah Research Foundation, Cognetix, Inc.Inventors: Baldomero Olivera, J. McIntosh, James Garrett, Craig Walker, Maren Watkins, Robert Jones
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Publication number: 20060014673Abstract: The present invention is directed to kappaA (?A) conopeptides and the use of these peptides for blocking the flow of potassium ions through voltage-gated potassium channels. The ?A conopeptides include unglycosylated and O-glycosylated peptides.Type: ApplicationFiled: July 6, 2005Publication date: January 19, 2006Applicants: Cognetix, Inc., University of Utah Research FoundationInventors: Richard Layer, Karen Pemberton, Robert Jones, James Garrett, Baldomero Olivera, J. McIntosh, David Hillyard, Michelle Grilley, Maren Watkins, Ameurfina Santos, Glenn Zafaralla, A. Craig
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Publication number: 20050271589Abstract: The present invention is directed to ?-superfamily conotoxin peptides, derivatives or pharmaceutically acceptable salts thereof. The present invention is further directed to the use of this peptide, derivatives thereof and pharmaceutically acceptable salts thereof for the treatment of disorders associated with voltage-gated ion channels, ligand gated channels and other receptors. The invention is further directed to nucleic acid sequences encoding the ?-superfamily conotoxin peptides and encoding ?-superfamily conotoxin propeptides, as well as the ?-superfamily conotoxin propeptides.Type: ApplicationFiled: August 8, 2005Publication date: December 8, 2005Applicants: University of Utah Research Foundation, Cognetix, Inc.Inventors: Robert Jones, Baldomero Olivera, Maren Watkins, James Garrett