Patents by Inventor Margaret Duncan

Margaret Duncan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccine and therapeutic delivery system
    Patent number: 9925257
    Abstract: The present invention relates to a new vaccine delivery system. In particular, the present invention includes compositions and methods of integrally transformed non-pathogenic, commensal bacteria that can express a nucleic acid molecule of a foreign polypeptide, wherein the nucleic acid molecule that encodes the foreign polypeptide is stably integrated into genomic DNA of the bacteria. The foreign polypeptide includes a vaccine antigen that elicits an immunogenic response, an inhibitor of a pathogen, or an immune booster or modulator.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: March 27, 2018
    Assignee: Forsyth Dental Infirmary for Children
    Inventors: Antonio Campos-Neto, Mark Cayabyab, Margaret Duncan
  • Vaccine and therapeutic delivery system
    Patent number: 9884108
    Abstract: The present invention relates to a new vaccine delivery system. In particular, the present invention includes compositions and methods of integrally transformed non-pathogenic, commensal bacteria that can express a nucleic acid molecule of a foreign polypeptide, wherein the nucleic acid molecule that encodes the foreign polypeptide is stably integrated into genomic DNA of the bacteria. The foreign polypeptide includes a vaccine antigen that elicits an immunogenic response, an inhibitor of a pathogen, or an immune booster or modulator.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: February 6, 2018
    Assignee: Forsyth Dental Infirmary for Children
    Inventors: Antonio Campos-Neto, Mark Cayabyab, Margaret Duncan
  • CONJUGATES FOR DELIVERY TO MITOCHONDRIA
    Publication number: 20170247674
    Abstract: The present disclosure relates generally to conjugates and their uses and production. More particularly, it concerns conjugates comprising an A44 or K39 gingipain adhesion peptide, or fragment thereof (e.g., an A44/K39 peptide portion) covalently attached to a heterologous agent that is capable of entering a cell by endocytosis and translocating to mitochondria.
    Type: Application
    Filed: October 14, 2015
    Publication date: August 31, 2017
    Inventors: Heike Boisvert, Margaret Duncan
  • Vaccine and Therapeutic Delivery System
    Publication number: 20160354462
    Abstract: The present invention relates to a new vaccine delivery system. In particular, the present invention includes compositions and methods of integrally transformed non-pathogenic, commensal bacteria that can express a nucleic acid molecule of a foreign polypeptide, wherein the nucleic acid molecule that encodes the foreign polypeptide is stably integrated into genomic DNA of the bacteria. The foreign polypeptide includes a vaccine antigen that elicits an immunogenic response, an inhibitor of a pathogen, or an immune booster or modulator.
    Type: Application
    Filed: June 3, 2016
    Publication date: December 8, 2016
    Inventors: Antonio Campos-Neto, Mark Cayabyab, Margaret Duncan
  • Vaccine and therapeutic delivery system
    Patent number: 9376686
    Abstract: The present invention relates to a new vaccine delivery system. In particular, the present invention includes compositions and methods of integrally transformed non-pathogenic, commensal bacteria that can express a nucleic acid molecule of a foreign polypeptide, wherein the nucleic acid molecule that encodes the foreign polypeptide is stably integrated into genomic DNA of the bacteria. The foreign polypeptide includes a vaccine antigen that elicits an immunogenic response, an inhibitor of a pathogen, or an immune booster or modulator.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: June 28, 2016
    Assignee: Forsyth Dental Infirmary for Children
    Inventors: Antonio Campos-Neto, Mark Cayabyab, Margaret Duncan
  • VACCINE AND THERAPEUTIC DELIVERY SYSTEM
    Publication number: 20160045591
    Abstract: The present invention relates to a new vaccine delivery system. In particular, the present invention includes compositions and methods of integrally transformed non-pathogenic, commensal bacteria that can express a nucleic acid molecule of a foreign polypeptide, wherein the nucleic acid molecule that encodes the foreign polypeptide is stably integrated into genomic DNA of the bacteria. The foreign polypeptide includes a vaccine antigen that elicits an immunogenic response, an inhibitor of a pathogen, or an immune booster or modulator.
    Type: Application
    Filed: January 23, 2015
    Publication date: February 18, 2016
    Inventors: Antonio Campos-Neto, Mark Cayabyab, Margaret Duncan
  • Vaccine and Therapeutic Delivery System
    Publication number: 20130095131
    Abstract: The present invention relates to a new vaccine delivery system. In particular, the present invention includes compositions and methods of integrally transformed non-pathogenic, commensal bacteria that can express a nucleic acid molecule of a foreign polypeptide, wherein the nucleic acid molecule that encodes the foreign polypeptide is stably integrated into genomic DNA of the bacteria. The foreign polypeptide includes a vaccine antigen that elicits an immunogenic response, an inhibitor of a pathogen, or an immune booster or modulator.
    Type: Application
    Filed: September 21, 2012
    Publication date: April 18, 2013
    Applicant: Forsyth Dental Infirmary for Children
    Inventors: Antonio Campos-Neto, Mark Cayabyab, Margaret Duncan
  • Marking template
    Patent number: 7770303
    Abstract: A marking template comprising a planar body portion having a central aperture, and a plurality of sets of apertures in the body portion, each set of apertures located a predetermined distance from the central aperture which enable rectangular patterns to be marked on a workpiece.
    Type: Grant
    Filed: December 8, 2005
    Date of Patent: August 10, 2010
    Inventors: Kym Joanne Graham, Ann Margaret Duncan
  • Marking Template
    Publication number: 20090113737
    Abstract: A marking template comprising a planar body portion having a central aperture, and a plurality of sets of apertures in the body portion, each set of apertures located a predetermined distance from the central aperture which enable rectangular patterns to be marked on a workpiece.
    Type: Application
    Filed: December 8, 2005
    Publication date: May 7, 2009
    Inventors: Kym Joanne Graham, Ann Margaret Duncan
  • Template to assist the process of circular sewing embroidery and the like
    Patent number: 7255051
    Abstract: A template (1) in the form of a thin disc is provided with segmental (3) and circular (4) markings, a central aperture (2), and apertures (5) which coincide with intersecting points on the markings enables centre point based positions to be plotted using the template (1) to assist in the process of circular sewing and embroidery.
    Type: Grant
    Filed: February 20, 2002
    Date of Patent: August 14, 2007
    Inventors: Kym Joanne Graham, Ann Margaret Duncan
  • Template to assist the process of circular sewing embroidery and the like
    Publication number: 20040211347
    Abstract: A template (1) in the form of a thin disc is provided with segmental (3) and circular (4) markings, a central aperture (2), and apertures (5) which coincide with intersecting points on the markings enables centre point based positions to be plotted using the template (1) to assist in the process of circular sewing and embroidery.
    Type: Application
    Filed: January 16, 2004
    Publication date: October 28, 2004
    Inventors: Kym Joanne Graham, Ann Margaret Duncan