Patents by Inventor Margaret M. Worden

Margaret M. Worden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CARRIER MATERIALS FOR PROTEIN DELIVERY
    Publication number: 20150072017
    Abstract: Osteogenic implants, carriers and concentrates are described, along with methods of making and using the same. The implants include a carrier and, optionally, an osteoinductive agent. The carrier includes a mineral component, a binder and, optionally, a collagen additive, while the osteoinductive agent may be a protein such as a bone morphogenetic protein.
    Type: Application
    Filed: September 9, 2013
    Publication date: March 12, 2015
    Applicant: Olympus Biotech Corporation
    Inventors: Hyun Kim, Shinichi Torii, Margaret M. Worden, Tetsuro Ogawa, Nozomi Komatsu
  • Iron regulation of the PpSEC10 transcriptional regulatory region of Pichia pastoris and methods of use
    Patent number: 6605450
    Abstract: Methods and compositions for the expression of nucleotide sequences are provided. Compositions comprise the nucleic acid sequences of the transcriptional regulatory region of the PpSEC10 gene of Pichia pastoris. Methods are provided to chemically regulate the PpSEC10 transcriptional control region by modulating the iron concentration in the culturing medium. The methods find use in regulating expression of nucleotide sequences. Furthermore, the methods of the invention can be used to regulate polypeptide expression, more particularly in regulating heterologous polypeptide expression, particularly using a yeast host cell as the expression system.
    Type: Grant
    Filed: May 24, 2001
    Date of Patent: August 12, 2003
    Assignee: Chiron Corporation
    Inventors: Robert J. Bishop, Kenneth A. Crawford, Margaret M. Worden