Patents by Inventor Maria Da Graca H. Vicente

Maria Da Graca H. Vicente has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Porphyrin Based neuton capture agents for cancer therapy
    Patent number: 7067653
    Abstract: The invention describes the synthesis of a panel of novel carbon-carbon linked carboranyl-containing 5,10,15,20-tetraphenylporphyrins bearing 25–44% boron by weight. In certain embodiments, a phenyl porphyrin compound has a carboranyl group attached to the phenyl group by a carbon-carbon linkage, wherein the phenyl group corresponds to the following formula where R7 through R11 are hydrogen, a carboranyl group, or are selected from the group consisting of hydroxyl, NMe3+, PMePh2+, PO(OH)2, SO3H, COOH, and NH2. In this embodiment, the carboranyl group is attached to the phenyl group by a carbon-carbon linkage, either one or two of R7 through R11 are other than hydrogen; and the phenyl porphyrin compound contains at least one phenyl group having at least one of said carboranyl groups.
    Type: Grant
    Filed: May 9, 2001
    Date of Patent: June 27, 2006
    Assignee: The Regents of the University of California
    Inventors: Maria Da Graca H. Vicente, Shankar Jayaram Shetty, Laurent Jaquinod, Kevin M. Smith