Abstract: A protective cover for remote control devices used for remotely operating televisions, VCR's, and music systems. The protective cover includes a thin, flexible main cover which is formed in a folded, elongate U-shaped configuration, interconnected at opposite pairs of longitudinal edges by a pair of flexible, expandable side panels. The main cover includes a transparent front through which the push buttons are visible and operable, a transparent top disposable adjacent the emitter cover through which the emitter of the remote control device can luminesce, a bottom panel, and a back panel. The remote control device is insertable into and removable from the protective cover using an extension of the top which forms a flap which is overlappable about a portion of the back of the protective cover to retain the remote control device, and secured using mating patches of a hook and loop fastener.