Abstract: The present disclosure provides anti-LILRB4 antibodies or antigen-binding fragments thereof, anti-LILRB4 chimeric antigen receptor protein, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same, and the uses thereof.

Abstract: Therapeutic Agents, Pharmaceutical Compositions, and Associated Biomarkers The invention relates to the identification of pharmaceutical compositions, therapeutic agents, peptides, nucleic acids, genetic constructs, vectors, cells, and medicaments, and their use in methods of treatment. For example, the treatment of neuropathological conditions, in particular Alzheimer's disease. Furthermore, provided herein are biomarkers, methods for their use, methods of diagnosis, methods of monitoring disease progression, and methods for monitoring medicament efficacy, in particular for Alzheimer's disease.

Abstract: A system and method for facilitating online education. The system provides for forming mentor groups that have desired mentor-mentee ration. The system can periodically check out for student dropouts from different courses and rearranges the mentor groups based on the dropout information.

Abstract: Embodiments relate to a coating, adhesive, sealant, elastomer, or reaction injection molded material forming polyurethane composition that comprises an isocyanate component that includes at least one isocyanate-terminated prepolymer, and an isocyanate reactive component that includes at least one Lewis acid catalyst polymerized polyether polyol having a weight average molecular weight from 200 g/mol to 1,000 g/mol, an average primary hydroxyl group content of at least 30%, and an average acetal content of at least 0.05 wt %.

Abstract: The invention relates to a biocompatible, flexible, bone-adhesive sheet that may suitably be applied in the treatment of bone defects, said bone-adhesive sheet comprising: a cohesive fibrous carrier structure comprising a three-dimensional interconnected interstitial space; distributed within the interstitial space, (i) a plurality of polymer particles comprising a water-soluble calcium-binding polymer, said water-soluble calcium-binding polymer carrying at least one calcium binding group or (ii) a plurality of reactive particles comprising an electrophilically activated water-soluble polymer and a plurality of bisphosphonate particles comprising nitrogenous bisphosphonate.

Abstract: The procedures for obtaining calcium oxide from eggshells with applications in food processes, refers to the plurality of procedures for obtaining Calcium Oxide (XAM), from eggshells, is based on a circular economy, in which waste eggshells are collected from different food establishments and agglomerated in the production center. The application of high temperatures (>900° C.) to the crushed eggshells, provides the transformation of calcium carbonate (CaCO3) into calcium oxide (CaO) with a pH that exceeds 12. The use of XAM as a raw material with the aforementioned characteristics, constitutes the ideal component to alkalinize different preparations in the production of different foods and particularly in the nixtamalization procedures for the production of corn dough prior to the production of tortillas, tamales, and other varieties of food.

Abstract: The invention relates to a one-component powder coating composition comprising a curing system comprising a curable resin and one or more curing additives for curing the curable resin, wherein the powder coating composition comprises: —one powder coating component comprising the curable resin and the one or more curing additives; and—in the range of from 0.

Abstract: A nickel-based alloy is coated with a silicate based nickel aluminide slurry diffusion coating.

Abstract: At least a part of a burner for a catalytic reactor is coated with a silicate based nickel aluminide slurry diffusion coating.

Abstract: A system and method of augmenting image data are described. In one embodiment, the method comprises receiving data of an image captured by a camera, the captured image including a region having a visible feature of an object, storing masking data defining a plurality of masks, each mask defining a respective masked portion of the region of the captured image, sampling pixel values at predefined locations of the captured image data, selecting at least one stored mask based on the sampled pixel values, modifying pixel values in the or each selected masked portion of the region of the captured image based on colourisation parameters, and outputting the captured image with the modified pixel values for display. In other embodiments pixel values of one or more identified regions of a face in a target image are modified based on the augmentation characteristics derived from corresponding identified regions of a face in a source image.

Abstract: A one-component powder coating composition is provided comprising a curable resin and one or more curing additives for curing the curable resin, wherein the powder coating composition comprises: one powder coating component comprising the curable resin and the one or more curing additives; and 1.0 to 20 wt % of a dry-blended inorganic particulate additive consisting of inorganic components i), ii), and iii), wherein component i) is non-coated aluminium oxide or non-coated silica, component ii) is aluminium hydroxide and/or aluminum oxyhydroxide, and component iii) is silica, and wherein the powder coating component has a particle size distribution with a Dv90 of at most 50 ?m and a Dv50 of at most 30 ?m.

Abstract: The present invention relates to the treatment of Epidermolysis Bullosa, particularly the recessive dystrophic subtype (RDEB), using the Clustered- Regularly Interspaced Short Palindromic Repeats (CRISPR) system. This technology offers the possibility to design a single guide RNA (sgRNA) which is incorporated into a CRISPR- associated protein (Cas9) to recognize and induce DNA double-strand breaks at a specific target location. DNA double-strand breaks will be repaired by homologous recombination (HR) in the presence of a donor sequence for Epidermolysis Bullosa gene repair. In the context of Epidermolysis Bullosa, this allows to repair the mutation/s causing the disease.

Abstract: The invention relates to a one-component powder coating composition comprising a curing system comprising a curable resin and one or more curing additives for curing the curable resin, wherein the powder coating composition comprises: - one powder coating component comprising the curable resin and the one or more curing additives; - in the range of from 0.1 to 15.0 wt% of a first dry-blended inorganic particulate additive consisting of inorganic components i), ii), and iii), wherein component i) is non-coated aluminium oxide or non-coated silica, component ii) is aluminium hydroxide and/or aluminium oxyhydroxide, and component iii) is silica, and wherein, if component i) is non-coated silica, component iii) does not comprise non-coated silica; and - in the range of from 0.1 to 35 wt% of a second dry-blended inorganic particulate additive, wherein the powder coating composition comprises in the range of from 1.

Abstract: The invention relates to a powder coating composition comprising a curing system comprising a curable resin and one or more curing additives for curing the curable resin, wherein the powder coating composition comprises: —two or more powder coating components with different contents of curable resin and/or at least one of the one or more curing additives; —in the range of from 0.

Abstract: The present invention provides multi-layer articles for use as a rail tie footings comprising, as the tie, an elongate rigid body having a substantially planar surface, and on the substantially planar surface comprising a a microcellular foam elastomeric pad, for example, of a substantially organic solvent free polyurethane, wherein the substantially planar surface has a peripheral landing on which there is no elastomeric pad and the elastomeric pad has a bulk density (ASTM D3676) of from 600 to 2000 Kg/m3 (0.6 to 2.0 g/cm3).

Abstract: Examples described herein relate to transitioning a playback session between portable playback devices such as “smart” headphones, earbuds, and handheld speakers with playback devices of a zone-based media playback system. Exemplary techniques facilitate continuity of playback when transitioning between locations (e.g., from at home to on-the-go or vice versa) or between listening paradigms (e.g., personal or out-loud playback of audio content). An example implementation includes detecting a swap trigger, determining the source playback device(s) and target playback device(s), and performing a playback session swap between the source playback device(s) and target playback device(s).

Abstract: Aspects of the present disclosure involve a system comprising a computer-readable storage medium storing a program and a method for performing operations comprising: receiving a request from a client device of a first user to engage in a shared augmented reality (AR) shopping experience with a second user; generating, for display on respective client devices of the first and second users, the shared AR shopping experience comprising a plurality of AR items that represent real-world products overlaid on a shared real-world environment of the first and second users; determining that the second user is interacting with a first AR item of the plurality of AR items; and in response to detecting that the second user is depicted in an image captured by the client device of the first user, overlaying the first AR item on the second user in the image.

Abstract: The present invention is related to packages to the food industry. Particularly, it is related to natural active packages for preserving bakery products against microorganism damage. More particularly, the invention is related to an antifungal active package comprising a multilayer polymer film with an internal polymer coating comprising mustard oil as natural essential oil having antifungal properties, useful for extending the half-life of celiac bakery products, preferably, a celiac bread.

Abstract: Aspects of the present disclosure involve a system comprising a computer-readable storage medium storing a program and a method for performing operations comprising: receiving, from a client device of a first user, a request from the first user to engage in an AR shopping experience curated by a store; identifying a first real-world product available for purchase from the store; receiving an image of a real-world environment of the first user; generating a first AR item that represents the first real-world product; comparing visual attributes of the first AR item to physical layouts of a plurality of real-world objects depicted in the image of the real-world environment; and overlaying the first AR item on a first real-world object of the plurality of real-world objects in the image responsive to comparing the visual attributes of the first AR item to the physical layouts of the plurality of real-world objects.

Abstract: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.