Patents by Inventor Maria Ourmanova

Maria Ourmanova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immortalized human stromal cell lines
    Patent number: 6541249
    Abstract: A method for the culture of hematopoietic cells and/or production of human cytokines using immortalized human stromal cell lines is provided. These immortalized stromal cell lines condition media such that the ability of the hematopoietic stem cells to self-replicate and/or differentiate is maintained by the media or the ability of the committed progenitors to expand and/or differentiate is maintained by the media. Further provided are irradiated and non-irradiated immortalized human stromal cells that synthesize cytokines, such as, IL-7, IL-8, IL-11, FLT3L, SCF, LIF, M-CSF, TGF-beta 1, GM-CSF, MIP-1alpha, G-CSF, and MCP-1.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: April 1, 2003
    Assignee: Human Genome Sciences, Inc.
    Inventors: Ruth E. Wager, Maria Ourmanova
  • Hematopoietic cells and methods based thereon
    Publication number: 20020001826
    Abstract: A method for the culture of hematopoietic cells and/or production of human cytokines using immortalized human stromal cell lines is provided. These immortalized stromal cell lines condition media such that the ability of the hematopoietic stem cells to self-replicate and/or differentiate is maintained by the media or the ability of the committed progenitors to expand and/or differentiate is maintained by the media. Further provided are irradiated and non-irradiated immortalized human stromal cells that synthesize cytokines, such as, IL-7, IL-8, IL-11, FLT3L, SCF, LIF, M-CSF, TGF-beta 1, GM-CSF, MIP-1alpha, G-CSF, and MCP-1.
    Type: Application
    Filed: December 21, 2000
    Publication date: January 3, 2002
    Inventors: Ruth E. Wager, Maria Ourmanova