Patents by Inventor Maria R. Kula

Maria R. Kula has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microbiologically-prepared diacetyl reductase
    Patent number: 5164314
    Abstract: A process for the enzymatic preparation of acetoin, particularly (+)-acetoin, employs a diacetyl reductase which can be obtained from a yeast or Lactobacillus strain.
    Type: Grant
    Filed: June 18, 1991
    Date of Patent: November 17, 1992
    Assignee: Forschungszentrum Juelich GmbH
    Inventors: Werner Hummel, Maria R. Kula, Frank Boermann
  • Enzymatic process for the preparation of optically active cyanohydrins
    Patent number: 5008192
    Abstract: An enzymatic reaction of aliphatic, aromatic or heteroaromatic aldehydes or ketones with hydrocyanic acid to form the corresponding (R)-cyanohydrins or (S)-cyanohydrins is carried out in an aqueous medium in the presence of (R)-oxynitrilase (4.1.2.10) or oxynitrilase (4.1.2.11) under acid conditions and at temperatures such that the competing chemical reaction and racemization are negligible compared with the enzymatic synthesis. The process is preferably carried out at a pH of .ltoreq.4.5 and at reaction temperatures between -5.degree. C. and +50.degree. C. The reaction is preferably carried out continuously, advantageously in an enzyme membrane reactor. Of particular interest is the conversion of aromatic aldehydes into the corresponding optically active cyanohydrins.
    Type: Grant
    Filed: January 30, 1989
    Date of Patent: April 16, 1991
    Assignees: Kernforschungsanlage Juelich GmbH, Degussa Aktiengesellschaft
    Inventors: Uwe Neidermeyer, Udo Kragl, Maria R. Kula, Christian Wandrey, Kyriakos Makrylaleas, Karlheinz Drauz