Patents by Inventor Marianne Bernice Ashford

Marianne Bernice Ashford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC DENDRIMERS
    Publication number: 20240115716
    Abstract: Disclosed are dendrimers of formula (I): and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising the dendrimer of formula (I) and methods of using the same for treating cancer.
    Type: Application
    Filed: June 14, 2023
    Publication date: April 11, 2024
    Inventors: Marianne Bernice ASHFORD, Iain GRANT, Edward John HENNESSY, William MCCOULL, Michael GIANNIS, Brian KELLY, David OWEN, John Paul SECRIST
  • Therapeutic dendrimers
    Patent number: 11717574
    Abstract: Disclosed are dendrimers of formula (I): and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising the dendrimer of formula (I) and methods of using the same for treating cancer.
    Type: Grant
    Filed: November 11, 2020
    Date of Patent: August 8, 2023
    Assignee: ASTRAZENECA AB
    Inventors: Marianne Bernice Ashford, Iain Grant, Edward John Hennessy, William Mccoull, Michael Giannis, Brian Kelly, David Owen, John Paul Secrist
  • THERAPEUTIC DENDRIMERS
    Publication number: 20210060172
    Abstract: Disclosed are dendrimers of formula (I): and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising the dendrimer of formula (I) and methods of using the same for treating cancer.
    Type: Application
    Filed: November 11, 2020
    Publication date: March 4, 2021
    Inventors: Marianne Bernice ASHFORD, Iain GRANT, Edward John HENNESSY, William MCCOULL, Michael GIANNIS, Brian KELLY, David OWEN, John Paul SECRIST
  • Therapeutic dendrimers
    Patent number: 10888624
    Abstract: Disclosed are dendrimers of formula (I): and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising the dendrimer of formula (I) and methods of using the same for treating cancer.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: January 12, 2021
    Assignee: ASTRAZENECA AB
    Inventors: Marianne Bernice Ashford, Iain Grant, Edward John Hennessy, William McCoull, Michael Giannis, Brian Kelly, David Owen, John Paul Secrist
  • THERAPEUTIC DENDRIMERS
    Publication number: 20200069810
    Abstract: Disclosed are dendrimers of formula (I): and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising the dendrimer of formula (I) and methods of using the same for treating cancer.
    Type: Application
    Filed: April 5, 2019
    Publication date: March 5, 2020
    Inventors: Marianne Bernice ASHFORD, Iain GRANT, Edward John HENNESSY, William MCCOULL, Michael GIANNIS, Brian KELLY, David OWEN, John Paul SECRIST
  • Therapeutic polymeric nanoparticles and methods of making and using same
    Patent number: 10577351
    Abstract: Described herein are polymeric nanoparticles that include a therapeutic agent which is 2-(3-((7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide (also known as AZD1152 hqpa) or a pharmaceutically acceptable salt thereof, and methods of making and using such therapeutic nanoparticles.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: March 3, 2020
    Assignee: ASTRAZENECA AB
    Inventors: Marianne Bernice Ashford, James Martin Nolan, III, Eyoung Shin, Young-Ho Song, Greg Troiano, Hong Wang
  • Therapeutic dendrimers
    Patent number: 10314920
    Abstract: Disclosed are dendrimers of formula (I): and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising the dendrimer of formula (I) and methods of using the same for treating cancer.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: June 11, 2019
    Assignee: AstraZeneca AB
    Inventors: Marianne Bernice Ashford, Iain Grant, Edward John Hennessy, William McCoull, Michael Giannis, Brian Kelly, David Owen, John Paul Secrist
  • THERAPEUTIC POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME
    Publication number: 20190092757
    Abstract: Described herein are polymeric nanoparticles that include a therapeutic agent which is 2-(3-((7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide (also known as AZD1152 hqpa) or a pharmaceutically acceptable salt thereof, and methods of making and using such therapeutic nanoparticles.
    Type: Application
    Filed: June 27, 2018
    Publication date: March 28, 2019
    Applicant: ASTRAZENECA AB
    Inventors: Marianne Bernice ASHFORD, James Martin NOLAN, III, Eyoung SHIN, Young-Ho SONG, Greg TROIANO, Hong WANG
  • THERAPEUTIC DENDRIMERS
    Publication number: 20180264127
    Abstract: Disclosed are dendrimers of formula (I): and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising the dendrimer of formula (I) and methods of using the same for treating cancer.
    Type: Application
    Filed: February 20, 2018
    Publication date: September 20, 2018
    Inventors: Marianne Bernice ASHFORD, Iain GRANT, Edward John HENNESSY, William MCCOULL, Michael GIANNIS, Brian KELLY, David OWEN, John Paul SECRIST
  • Therapeutic polymeric nanoparticles and methods of making and using same
    Patent number: 10047072
    Abstract: Described herein are polymeric nanoparticles that include a therapeutic agent which is 2-(3-((7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide (also known as AZD1152 hqpa) or a pharmaceutically acceptable salt thereof, and methods of making and using such therapeutic nanoparticles.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: August 14, 2018
    Assignee: ASTRAZENECA AB
    Inventors: Marianne Bernice Ashford, James Martin Nolan, III, Eyoung Shin, Young-Ho Song, Greg Troiano, Hong Wang
  • THERAPEUTIC POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME
    Publication number: 20150140104
    Abstract: Described herein are polymeric nanoparticles that include a therapeutic agent which is 2-(3-((7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide (also known as AZD1152 hqpa) or a pharmaceutically acceptable salt thereof, and methods of making and using such therapeutic nanoparticles.
    Type: Application
    Filed: September 15, 2014
    Publication date: May 21, 2015
    Applicant: ASTRAZENECA AB
    Inventors: Marianne Bernice ASHFORD, James Martin NOLAN III, Eyoung SHIN, Young-Ho SONG, Greg TROIANO, Hong WANG
  • N-(-3-METHOXY-5-METHYLPYRAZIN-2-YL)-2-(4-'1,3,4-OXADIAZOL-2-YL!PHENYL)PYRIDINE-3 SULPHONAMIDE AS AN ANTICANCER AGENT
    Publication number: 20110003831
    Abstract: The use of N-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide, or a pharmaceutically acceptable salt thereof, in the treatment of cancer and/or pain in a warm blooded animal such as man is described.
    Type: Application
    Filed: September 13, 2010
    Publication date: January 6, 2011
    Applicant: ASTRAZENECA AB
    Inventors: David Williams Tonge, Sian Tomiko Taylor, Francis Thomas Boyle, Andrew Mark Hughes, Donna Johnson, Marianne Bernice Ashford, Nigel Charles Barrass
  • N-(-3-methoxy-5-methylpyrazin-2-yl)-2-(4-?1,3,4-oxadiazol-2-yl-phenyl)pyridine-3 sulphonamide as an anticancer agent
    Patent number: 7820679
    Abstract: The use of N-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide, or a pharmaceutically acceptable salt thereof, in the treatment of cancer and/or pain in a warm blooded animal such as man is described.
    Type: Grant
    Filed: August 20, 2003
    Date of Patent: October 26, 2010
    Assignee: AstraZeneca AB
    Inventors: David William Tonge, Sian Tomiko Taylor, Francis Thomas Boyle, Andrew Mark Hughes, Donna Johnstone, Marianne Bernice Ashford, Nigel Charles Barrass