Patents by Inventor Marianne Mangeney

Marianne Mangeney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutated HIV Nef for modulating immunity
    Patent number: 8795685
    Abstract: Described is the use of a mutation of at least one amino acid in the immunosuppressive domain of a HIV or SIV accessory protein, for modulating the immunosuppressive property of the protein.
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: August 5, 2014
    Assignees: Institut Gustave Roussy, Centre National de la Recherche Scientifique, Universite Paris Sud XI
    Inventors: Martial Renard, Marianne Mangeney, Thierry Heidmann
  • Mutated env sequence involved in the modulation of the immunosuppressive effect of viral proteins
    Patent number: 8597657
    Abstract: Mutated viral ENV proteins having mutations in the immunosuppressive domain (ISU) of the transmembrane subunit (TM) have decreased immunosuppressive activity with respect to the wild-type ENV protein. Pharmaceutical compositions that include the protein and nucleic acids coding for the protein are also disclosed.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: December 3, 2013
    Assignees: Institut Gustave Roussy, Centre National de la Recherche Scientifique, Universite Paris Sud XI
    Inventors: Martial Renard, Marianne Mangeney, Thierry Heidmann
  • POLYPEPTIDE SEQUENCE INVOLVED IN THE MODULATION OF THE IMMUNOSUPPRESIVE EFFECT OF VIRAL PROTEINS
    Publication number: 20120189647
    Abstract: Mutated viral ENV proteins having mutations in the immunosuppressive domain (ISU) of the transmembrane subunit (TM) have decreased immunosuppressive activity with respect to the wild-type ENV protein. Pharmaceutical compositions that include the protein and nucleic acids coding for the protein are also disclosed.
    Type: Application
    Filed: February 17, 2012
    Publication date: July 26, 2012
    Applicants: Institut Gustave Roussy, Universite Paris Sud X1, Centre National De La Recherche Scientifique
    Inventors: Martial RENARD, Marianne Mangeney, Thierry Heidmann
  • Polypeptide sequence involved in the modulation of the immunosuppressive effect of viral proteins
    Patent number: 8178657
    Abstract: The present invention relates to a polypeptide having a sequence of 7 to 20 amino acid residues, which is capable of modulating the immunosuppressive properties of a viral protein or a fragment thereof, against the host in which it is expressed (immunosuppression-modulatory sequence) when it substitutes the homologous sequence of the viral protein or fragment, the polypeptide including the minimum following consensus amino acid sequence: X1Y9Y10Y11CY12X2 wherein, X1 and X2 are selected to impact on the immunosuppressive properties, and Y9 to Y12 represent variable amino acid residues.
    Type: Grant
    Filed: March 30, 2005
    Date of Patent: May 15, 2012
    Assignees: Institut Gustave Roussy, Centre National de la Recherche Scientifique, Universite Paris Sud XI
    Inventors: Martial Renard, Marianne Mangeney, Thierry Heidmann
  • Mutated Hiv Nef For Modulating Immunity
    Publication number: 20080220008
    Abstract: Described is the use of a mutation of at least one amino acid in the immunosuppressive domain of a HIV or SIV accessory protein, for modulating the immunosuppressive property of the protein.
    Type: Application
    Filed: August 17, 2005
    Publication date: September 11, 2008
    Applicants: INSTITUT GUSTAVE ROUSSY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Martial Renard, Marianne Mangeney, Thierry Heidmann
  • Polypeptide Sequence Involved in the Modulation of the Immunosuppresive Effect of Viral Proteins
    Publication number: 20080008683
    Abstract: The present invention relates to a polypeptide having a sequence of 7 to 20 amino acid residues, which is capable of modulating the immunosuppressive properties of a viral protein or a fragment thereof, against the host in which it is expressed (immunosuppression-modulatory sequence) when it substitutes the homologous sequence of the viral protein or fragment, the polypeptide including the minimum following consensus amino acid sequence: X1Y9Y10Y11CY12X2 wherein, X1 and X2 are selected to impact on the immunosuppressive properties, and Y9 to Y12 represent variable amino acid residues.
    Type: Application
    Filed: March 30, 2005
    Publication date: January 10, 2008
    Applicants: INSTITUT GUSTAVE ROUSSY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS SUB X1
    Inventors: Martial Renard, Marianne Mangeney, Thierry Heidmann