Patents by Inventor Mariano Mumpower
Mariano Mumpower has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11975172Abstract: An engagement mechanism associated with a reciprocally movable piston of a fluid injector is configured for releasably engaging an engagement portion at a proximal end of a rolling diaphragm syringe having a flexible sidewall configured for rolling upon itself when acted upon by the piston. The engagement mechanism has a plurality of engagement elements reversibly and radially movable relative to the engagement portion of the syringe between a first position, where the plurality of engagement elements are disengaged from the engagement portion of the syringe, and a second position, where the plurality of engagement elements are engaged with the engagement portion of the syringe. The engagement mechanism further has a drive mechanism for moving the plurality of engagement elements between the first position and the second position.Type: GrantFiled: December 17, 2021Date of Patent: May 7, 2024Assignee: BAYER HEALTHCARE LLCInventors: Kevin Cowan, Michael Spohn, Adam Steege, Jessie Delgado, Keith Lipford, Chet Larrow, Mariano Mumpower, Danica Gordon
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Patent number: 11957864Abstract: An exemplary pharmaceutical compounding system and device for mixing materials from at least two distinct material sources can include a transfer set and junction structure that has a junction body, a first inlet port located at a first portion of the junction body, a second inlet port located at a second portion of the junction body, and an outlet port located at a third portion of the junction body. The junction structure can be configured to mix fluid received from both the first inlet port and second inlet port and to deliver the fluid to the outlet port. The junction structure can also include attachment structure located on the junction body and configured to attach the junction structure to the housing of the compounding device at a location downstream of a pump system.Type: GrantFiled: November 4, 2019Date of Patent: April 16, 2024Assignee: B. Braun Medical Inc.Inventors: Mike Janders, Mariano Mumpower, Benjamin R. Lane
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Patent number: 11944588Abstract: In one aspect, the subject invention is directed to a method of preparing a combinatorial drug delivery device based on a predetermined selection of drug components. The method includes: preparing a plurality of containers, each accommodating one of the selected drug components; coupling the containers to a common outlet so that the drug components may be extracted from the containers and dispensed through the common outlet; and, applying negative pressure to extract the drug components from the containers and urge the drug components towards the common outlet.Type: GrantFiled: May 10, 2019Date of Patent: April 2, 2024Assignee: Bristol-Myers Squibb CompanyInventors: Martin John McLoughlin, Stephen Lawrence Zieminski, Chester Larrow, Mariano Mumpower
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Compounding device system, software and method for controlling the process of compounding admixtures
Patent number: 11911736Abstract: An exemplary compounding method of controlling a compounding device to prepare an admixture of at least two distinct material sources can include examining material source solutions for incompatibility of the ingredients and operating a first and a second pump to prevent one of the incompatible source solutions from entering a common flow path. The processing method can detect degradation of a fluid line by evaluating one or more of calibration error rate data, cumulative volumetric flow data, or cumulative pump operation data. The processing method can also selectively transfer a first group of source solutions using the first pump, receiving pump data from one or more sensors that sense actions of the pumps, applying fluid correction factors and calculating discrete pump movements, the pump movements being indicative of an amount of source solution displacement by a pump, and operating the pumps to selectively dispense the source solution amounts according to a preparation order.Type: GrantFiled: December 7, 2019Date of Patent: February 27, 2024Assignee: B. BRAUN MEDICAL INC.Inventors: Michael Y. Brown, Jacob Albro Cowperthwaite, David Earl Hershey, II, Benjamin Richard Lane, Aaron S. Pearl, Mariano Mumpower, Jeffrey Manfred Gunnarsson, James Austin Kendall, Christopher Allen Gray, Stephanne Suzann Flint, Mark David Steenbarger, Alice Maria Weintraut -
Publication number: 20240009081Abstract: In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.Type: ApplicationFiled: September 23, 2023Publication date: January 11, 2024Inventors: Martin John McLoughlin, Chester Larrow, Mariano Mumpower
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Patent number: 11801199Abstract: In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.Type: GrantFiled: October 26, 2022Date of Patent: October 31, 2023Assignee: BRISTOL-MYERS SQUIBB COMPANYInventors: Martin John McLoughlin, Chester Larrow, Mariano Mumpower
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Patent number: 11717668Abstract: An exemplary compounding system and device for mixing materials can include a housing, a first material source and a second material source. A first fluid line can be operationally connected to the housing and configured to transport a first volume of fluid per unit time from the first material source to a final container. A second fluid line can be operationally connected to the housing and configured to transport a second volume of fluid per unit time from the second material source to the final container.Type: GrantFiled: November 29, 2018Date of Patent: August 8, 2023Assignee: B. Braun Medical Inc.Inventors: Michael Y. Brown, Benjamin R. Lane, Mariano Mumpower
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Publication number: 20230138535Abstract: An exemplary compounding system and method can include a transfer set that includes a manifold for assisting in transferring a plurality of ingredients from supply container(s) to a final container. The manifold can include a first channel in fluid communication with at least one primary ingredient, and a second channel in fluid communication with a plurality of secondary ingredients. The first channel and second channel can be in fluid isolation from each other such that the at least one primary ingredient does not mix with the plurality of secondary ingredients within the manifold. The transfer set can include a plurality of inlet lines in fluid communication with the manifold and two outlet lines configured for connection to two separate pumps and eventually being in fluid communication with the final container.Type: ApplicationFiled: December 30, 2022Publication date: May 4, 2023Inventors: Karl Konrad, JR., Joel Bartholomew, Mike Janders, Linda M. Ammermann, Benjamin R. Lane, Mariano Mumpower, Aaron S. Pearl
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Publication number: 20230044334Abstract: In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.Type: ApplicationFiled: October 26, 2022Publication date: February 9, 2023Inventors: Martin John McLoughlin, Chester Larrow, Mariano Mumpower
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Publication number: 20230017492Abstract: The present disclosure relates to a dose detection system for use in combination with a medication delivery device in which a dose setting member rotates relative to an actuator during dose delivery. The dose detection system includes a module which is removably attached to the medication delivery device. The module includes a dosing component attached to the actuator during dose delivery. The dosing component includes a light source and a light sensor. A sensed element is attached to the dose setting member and includes surface features detectable by the light sensor.Type: ApplicationFiled: September 19, 2022Publication date: January 19, 2023Inventors: Roy Howard BYERLY, Collin Hunter GRIMES, Jeffrey Manfred GUNNARSSON, Chenrong MENG, Andre Rafael MINOLI, Mariano MUMPOWER, Brian Gregory MURPHY, Aaron Samuel PEARL, Abbie Lynn SHOEMAKER, Samuel Robert ZSCHACK
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Patent number: 11547793Abstract: An engagement mechanism associated with a reciprocally movable piston of a fluid injector is configured for releasably engaging an engagement portion at a proximal end of a rolling diaphragm syringe having a flexible sidewall configured for rolling upon itself when acted upon by the piston. The engagement mechanism has a plurality of engagement elements reversibly and pivotally movable about a pivot pin relative to the engagement portion of the syringe between a first position, where the plurality of engagement elements are disengaged from the engagement portion of the syringe, and a second position, where the plurality of engagement elements are pivotally movable about the pivot pin in a radially inward direction to engage with the engagement portion of the syringe. The engagement mechanism further has a drive mechanism for moving the plurality of engagement elements between the first position and the second position.Type: GrantFiled: October 16, 2017Date of Patent: January 10, 2023Assignee: BAYER HEALTHCARE LLCInventors: Kevin Cowan, Michael Spohn, Barry Tucker, James Dedig, Gregory Johnston, Michael McDermott, David Berry, Adam Steege, Keith Lipford, Chet Larrow, Mariano Mumpower, Danica Gordon
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Patent number: 11541222Abstract: An exemplary compounding system and method can include a transfer set that includes a manifold for assisting in transferring a plurality of ingredients from supply container(s) to a final container. The manifold can include a first channel in fluid communication with at least one primary ingredient, and a second channel in fluid communication with a plurality of secondary ingredients. The first channel and second channel can be in fluid isolation from each other such that the at least one primary ingredient does not mix with the plurality of secondary ingredients within the manifold. The transfer set can include a plurality of inlet lines in fluid communication with the manifold and two outlet lines configured for connection to two separate pumps and eventually being in fluid communication with the final container.Type: GrantFiled: July 20, 2017Date of Patent: January 3, 2023Assignee: B. BRAUN MEDICAL INC.Inventors: Karl Konrad, Jr., Joel Bartholomew, Mike Janders, Linda M. Ammermann, Benjamin R. Lane, Mariano Mumpower, Aaron S. Pearl
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Patent number: 11524117Abstract: The present disclosure relates to a dose detection system for use in combination with a medication delivery device in which a dose setting member rotates relative to an actuator during dose delivery. The dose detection system includes a module which is removably attached to the medication delivery device. The module includes a dosing component attached to the actuator during dose delivery. The dosing component includes a light source and a light sensor. A sensed element is attached to the dose setting member and includes surface features detectable by the light sensor.Type: GrantFiled: August 17, 2018Date of Patent: December 13, 2022Assignee: Eli Lilly and CompanyInventors: Roy Howard Byerly, Collin Hunter Grimes, Jeffrey Manfred Gunnarsson, Chenrong Meng, Andre Rafael Minoli, Mariano Mumpower, Brian Gregory Murphy, Aaron Samuel Pearl, Abbie Lynn Shoemaker, Samuel Robert Zschack
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Publication number: 20220362105Abstract: A valving arrangement is provided herein for regulating fluidics of modules usable in a combinatorial drug delivery device. The valving includes a slidable piston valve, adjustable to selectively seal an outlet path from a drug vial and a sealing port, in parallel to a vent, for selectively sealing an inlet path to the drug vial. Advantageously, the subject invention allows for applied negative pressure to adjust the valving to allow flow between serially-connected modules forming a drug delivery device.Type: ApplicationFiled: November 9, 2020Publication date: November 17, 2022Inventors: Martin John McLoughlin, Stephen Lawrence Zieminski, Mark Steven Howansky, Mariano Mumpower, Melanie Marie Springer, Katherine Alina Goetz, Benjamin Richard Lane
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Patent number: 11497685Abstract: In one aspect, a combinatorial drug delivery device is provided for delivering a predetermined selection of drug components. The device includes a plurality of modules, each including: a body having an interior volume; a spike plate movably disposed in the interior volume, the spike plate having a protruding cannula and first and second ports. The device also includes a base tray which includes: a framework defining a plurality of wells, each of the wells formed to insertingly receive one of the modules; for each of the wells, first and second inlet ports formed to interface with the first and second ports of the module being received in the respective well; passageways to connect certain wells with adjacent wells to permit fluid flow therebetween. For each of the wells, the spike plate of the respective module being maintained in a stationary position with the module being inserted into the well.Type: GrantFiled: May 10, 2019Date of Patent: November 15, 2022Assignee: Bristol-Myers Squibb CompanyInventors: Martin John McLoughlin, Chester Larrow, Mariano Mumpower
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Publication number: 20220288377Abstract: An exemplary compounding system and method can include two pump heads for simultaneously drawing two different fluids from at least two separate input containers such that the at least two different fluids are mixed and distributed to an output container. The system can include a manifold that maintains separation of certain of the different fluids until after passing by a first pump and a second pump and/or additional pumps. A junction can be placed in the fluid line downstream of the first and second pumps and/or additional pumps such that all or some of the fluids are mixed prior to output to the output container. The method of using the system can include incorporating software that selects various fluids at certain times and sequences to ensure optimum efficiency and safety for the system, and can continue compounding actions even when an input supply container runs out or otherwise fails to supply a particular fluid/material.Type: ApplicationFiled: June 1, 2022Publication date: September 15, 2022Inventors: Michael Y. Brown, Mariano Mumpower, Jake A. Cowperthwaite, Jamie Kendall, Jeremy C. Savage, Chet B. Larrow, Alex K. Flamm, Dave E. Hershey, Aaron S. Pearl, Benjamin R. Lane, Karl Konrad, JR., Joel Bartholomew, Mike Janders, Edwin Burnard
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Patent number: 11357966Abstract: An exemplary compounding system and method can include two pump heads for simultaneously drawing two different fluids from at least two separate input containers such that the at least two different fluids are mixed and distributed to an output container. The system can include a manifold that maintains separation of certain of the different fluids until after passing by a first pump and a second pump and/or additional pumps. A junction can be placed in the fluid line downstream of the first and second pumps and/or additional pumps such that all or some of the fluids are mixed prior to output to the output container. The method of using the system can include incorporating software that selects various fluids at certain times and sequences to ensure optimum efficiency and safety for the system, and can continue compounding actions even when an input supply container runs out or otherwise fails to supply a particular fluid/material.Type: GrantFiled: April 23, 2015Date of Patent: June 14, 2022Assignee: B. Braun Medical Inc.Inventors: Benjamin R. Lane, Mariano Mumpower, Jake A. Cowperthwaite, Jamie Kendall, Jeremy C. Savage, Chet B. Larrow, Alex K. Flamm, Dave E. Hershey, Aaron S. Pearl, Michael Y. Brown, Karl Konrad, Jr., Joel Bartholomew, Mike Janders, Edwin Burnard
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Publication number: 20220105265Abstract: An engagement mechanism associated with a reciprocally movable piston of a fluid injector is configured for releasably engaging an engagement portion at a proximal end of a rolling diaphragm syringe having a flexible sidewall configured for rolling upon itself when acted upon by the piston. The engagement mechanism has a plurality of engagement elements reversibly and radially movable relative to the engagement portion of the syringe between a first position, where the plurality of engagement elements are disengaged from the engagement portion of the syringe, and a second position, where the plurality of engagement elements are engaged with the engagement portion of the syringe. The engagement mechanism further has a drive mechanism for moving the plurality of engagement elements between the first position and the second position.Type: ApplicationFiled: December 17, 2021Publication date: April 7, 2022Inventors: Kevin Cowan, Michael Spohn, Adam Steege, Jessie Delgado, Keith Lipford, Chet Larrow, Mariano Mumpower, Danica Gordon
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Publication number: 20220023531Abstract: In one aspect, the subject invention is directed to a method of preparing a combinatorial drug delivery device based on a predetermined selection of drug components. The method includes: preparing a plurality of containers, each accommodating one of the selected drug components; coupling the containers to a common outlet so that the drug components may be extracted from the containers and dispensed through the common outlet; and, applying negative pressure to extract the drug components from the containers and urge the drug components towards the common outlet.Type: ApplicationFiled: May 10, 2019Publication date: January 27, 2022Inventors: Martin John McLoughlin, Stephen Lawrence Zieminski, Chester Larrow, Mariano Mumpower
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Patent number: 11207462Abstract: An engagement mechanism associated with a reciprocally movable piston of a fluid injector is configured for releasably engaging an engagement portion at a proximal end of a rolling diaphragm syringe having a flexible sidewall configured for rolling upon itself when acted upon by the piston. The engagement mechanism has a plurality of engagement elements reversibly and radially movable relative to the engagement portion of the syringe between a first position, where the plurality of engagement elements are disengaged from the engagement portion of the syringe, and a second position, where the plurality of engagement elements are engaged with the engagement portion of the syringe. The engagement mechanism further has a drive mechanism for moving the plurality of engagement elements between the first position and the second position.Type: GrantFiled: October 16, 2017Date of Patent: December 28, 2021Assignee: BAYER HEALTHCARE LLCInventors: Kevin Cowan, Michael Spohn, Adam Steege, Jessie Delgado, Keith Lipford, Chet Larrow, Mariano Mumpower, Danica Gordon