Patents by Inventor Marie-Christine Levy

Marie-Christine Levy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6197757
    Abstract: Particles comprising an outer wall formed of one or more saccharide components selected from the group consisting of monosaccharides and oligosaccharides crosslinked by interfacial crosslinking in emulsion, preferably at room temperature, with a polyfunctional acylating crosslinking agent to produce ester linkages between the acylatable hydroxyl group(s) of the primary alcohol(s) of the saccharide component and the acyl groups of the polyfunctional acylating agent. These particles can be used for the manufacture of cosmetic, pharmaceutical and food compositions.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: March 6, 2001
    Inventors: Eric Perrier, Sylvie Rey-Goutenoire, Chantal Buffevant, Marie-Christine Levy, Nadine Pariot, Florence Edwards, Marie-Christine Andry
  • Patent number: 6132750
    Abstract: The invention relates to small sized particles.These particles comprise at least on the surface thereof a wall composed of a mixture of at least one protein and at least one polysaccharide which are cross-linked, preferably by interfacial cross-linking with a polyfunctional acylating agent which forms at least amide and ester bonds, and optionally anhydride bonds with amine, hydroxyl or carboxyl functions of the protein and of the polysaccharide, and which comprise hydroxamic groups on the surface thereof for chelating metal ions.These particles can be used in cosmetics or in pharmacy notably for the chelation or release of metal ions.
    Type: Grant
    Filed: July 1, 1998
    Date of Patent: October 17, 2000
    Assignee: Coletica
    Inventors: Eric Perrier, Chantal Buffevant, Isabelle Bonnet, Marie-Christine Levy
  • Patent number: 5912016
    Abstract: The invention relates to particles. These particles comprise, at least on the surface, a wall formed of plant proteins crosslinked particularly by means of interfacial crosslinking between the plant proteins and an acylating polyfunctional crosslinking agent comprising at least two acylating groups, covalent bonds being formed between the acylatable groups of the proteins and the acyl groups of the acylating polyfunctional crosslinking agent. These particles are used for the manufacture of a cosmetic, pharmaceutical, dermatological or food composition.
    Type: Grant
    Filed: September 9, 1997
    Date of Patent: June 15, 1999
    Assignee: Coletica
    Inventors: Eric Perrier, Marie-Christine Levy, Patricia Lacazette, Chantal Buffevant
  • Patent number: 5780060
    Abstract: Microcapsules based on crosslinked plant polyphenols are described. These microcapsules are obtained by the interfacial crosslinking of plant polyphenols, particularly flavonoids. When incorporated in a composition such as a cosmetic, pharmaceutical, dietetic or food composition, these microcapsules make it possible to prevent any impairment of this composition, in particular any color modification, while at the same time preserving the activity, especially the anti-free radical and/or antioxidizing activity, of the plant polyphenols, particularly the flavonoids.
    Type: Grant
    Filed: September 27, 1995
    Date of Patent: July 14, 1998
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Marie-Christine Levy, Marie-Christine Andry
  • Patent number: 5691060
    Abstract: The invention relates to microparticles, particularly microcapsules and their fabrication method. Said microparticles, and particularly said microcapsules, are characterized in that they have a wall made of the product obtained from the reaction between a polysaccharide carrying esterified carboxylic groups and a polyaminated or polyhydroxylated substance, particularly through a transacylation reaction. Said microparticles or said microcapsules are useful for the fabrication of cosmetic, pharmaceutical or food product compositions.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: November 25, 1997
    Assignee: Coletica
    Inventor: Marie-Christine Levy
  • Patent number: 5672301
    Abstract: The method for producing microparticles is characterized in that it comprises the following steps: preparation of an emulsion of a solution of a substance or a mixture of substances in a dispersing liquid wherein said substance or said mixture are substantially insoluble; incorporating to said dispersed phase a chemical agent substantially insoluble in the dispersing liquid so as to cause within the dispersed phase a chemical or physicochemical reaction responsible for the formation of microparticles which are then isolated.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: September 30, 1997
    Assignee: Coletica
    Inventors: Isabelle Orly, Marie-Christine Levy, Eric Perrier
  • Patent number: 5635609
    Abstract: Particles, preparation methods therefor, and compositions containing same. The particles include at least one esterified polysaccharide and at least one polyamine, as well as at least one gellable polysaccharide when neither the esterified polysaccharide nor the polyamine can be gelled under the selected operating conditions. Said particle includes, at least on its surface, a membrane consisting of the product of the transacylation reaction between the esterified polysaccharide and said polyamine within an optionally gellable gel, said reaction causing the formation of covalent amide bonds. Such particles may be used to encapsulated various active principles useful in the fields of cosmetics, pharmaceuticals and agri-foodstuffs, enzymes, cells and micro-organisms.
    Type: Grant
    Filed: July 20, 1995
    Date of Patent: June 3, 1997
    Assignee: Coletica
    Inventors: Marie-Christine Levy, Florence Edwards-Levy, Isabelle Orly
  • Patent number: 5622656
    Abstract: The invention relates to microcapsules with a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, and to processes for the manufacture of the said microcapsules.According to the invention, the microcapsules comprise a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, the proportion of polyholosides, for example glycosaminoglycans, relative to the atelocollagen preferably being between 18 and 50% by weight. These microcapsules can be manufactured either by a process involving interfacial crosslinking or by the extrusion of a laminar flow which is broken up by vibrations into individual droplets, which fall into a crosslinking bath.These microcapsules are biocompatible by virtue of the presence of atelocollagen, which has most of the advantageous properties of collagen, namely a very low antigenicity and a perfect biodegradability.
    Type: Grant
    Filed: October 25, 1994
    Date of Patent: April 22, 1997
    Assignee: Societe Anonyme: Bioetica
    Inventors: Alain Huc, Marie-Christine Levy, Chantal Buffevant, Marie-Christine Andry
  • Patent number: 5395620
    Abstract: The invention relates to microcapsules with a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, and to processes for the manufacture of the said microcapsules. According to the invention, the microcapsules comprise a mixed wall of crosslinked atelocollagen and polyholosides, for example glycosaminoglycans, the proportion of polyholosides, for example glycosaminoglycans, relative to the atelocollagen preferably being between 18 and 50% by weight. These microcapsules can be manufactured either by a process involving interfacial crosslinking or by the extrusion of a laminar flow which is broken up by vibrations into individual droplets, which fall into a crosslinking bath. These microcapsules are biocompatible by virtue of the presence of atelocollagen, which has most of the advantageous properties of collagen, namely a very low antigenicity and a perfect biodegradability.
    Type: Grant
    Filed: June 8, 1993
    Date of Patent: March 7, 1995
    Assignee: Coletica
    Inventors: Alain Huc, Marie-Christine Levy, Chantal Buffevant, Marie-Christine Andry
  • Patent number: 4780321
    Abstract: A process for preparing microcapsules containing a pharmaceutically active substance of a water soluble nature is provided, which involves dissolving a mixture containing at least one water soluble polyholoside or water soluble derivative of a polyholoside, at least one protein, and the pharmaceutically active substance in an alkaline aqueous solution having a pH preferably above 10, the solution being emulsified by dispersion within an immiscible organic solvent, by addition of an emulsifier of the water in oil type and by stirring. Thereafter, a reticulation agent dissolved in the same immiscible organic solvent is added to the previously obtained emulsion being stirred, and the stirring is continued until interfacial reticulation is achieved. The microcapsules are then isolated by diluting the reaction mixture with solvent, or a mixture of solvents and then centrifugation or decantation.
    Type: Grant
    Filed: August 7, 1986
    Date of Patent: October 25, 1988
    Assignee: Centre National de la Recherche Scientifique (CNRS)
    Inventors: Marie Christine Levy, Bertrand Gourdier