Patents by Inventor Marie-Christine Rio

Marie-Christine Rio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for diagnosis and therapy of cancer and composition useful therein
    Publication number: 20050032101
    Abstract: Polynucleotide and polypeptide SMAGP are specific for tumors. Diagnosis of SMAGP is therefore valuable for diagnosis of tumors. Antibodies against SMAGP are, besides their value in diagnosis, useful as therapeutic agents in the treatment of tumors.
    Type: Application
    Filed: July 21, 2004
    Publication date: February 10, 2005
    Inventors: Marie-Christine Rio, Nesrine Tarbe de Saint Hardouin, Ulrich Weidle
  • Phosphinic pseudo-peptides that may be used as matrix zinc metalloprotease inhibitors
    Patent number: 6630501
    Abstract: The invention relates to pseudo-peptides according to the formula: wherein R1 is a group inhibiting an amine function, or an amino acid residue or peptide with an inhibited terminal amino function, R2 represents the lateral chain of a natural or non-natural amino acid, R3 represents: 1) the lateral chain of a natural amino acid except for Gly and Ala, not substituted or substituted by an aryl group, 2) an aralkyl group, or 3) an alkyl group comprising at least 3 carbon atoms, and R4 represents a lateral chain of natural or non-natural amino acid. They are useful as matrix zinc metalloprotease inhibitors, particularly in the treatment of cancer.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: October 7, 2003
    Assignees: Commissariat a l'energie Atomique, Institut National de la Recherche Medical, Centre National de la Recherche Scientifique
    Inventors: Vincent Dive, Philippe Cuniasse, Marie-Christine Rio, Paul Basset, Athanasios Yotakis, Fabrice Beau, Stamania Vassiliou
  • Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis and encoded polypeptides
    Patent number: 5981218
    Abstract: The present invention relates to four novel human genes amplified and overexpressed in breast carcinoma and located on the q11-q21.3 region of chromosome 17. The four novel genes are useful in breast cancer prognosis. The present invention also relates to a fifth novel human gene expressed in breast carcinoma and located on chromosome 6q22-q23. A sixth novel gene is also described that is the murine homolog of the human D52 gene. The genes and gene fragments of the present invention are themselves useful as DNA and RNA probes for gene mapping by in situ hybridization with chromosomes and for detecting gene expression in human tissues (including breast and lymph node tissues) by Northern blot analysis.
    Type: Grant
    Filed: July 31, 1996
    Date of Patent: November 9, 1999
    Assignees: Bristol-Myers Squibb Company, Institut National de la Sante et de la Recherche Medicale, Centre National de la Recherche Scientifique, Universite Louis Pasteur
    Inventors: Marie-Christine Rio, Catherine Tomasetto, Paul Basset, Jennifer Byrne