Patents by Inventor Marie E. Egan

Marie E. Egan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
    Patent number: 8058314
    Abstract: This invention provides the methodology and agents for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention of proteins. Thus, the methods and agents of the present invention provide for the release of normally retained proteins from the endoplasmic reticulum. The present invention is particularly useful for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention or degradation of mis-assembled or mis-folded proteins.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: November 15, 2011
    Assignee: Yale University
    Inventors: Michael J. Caplan, Marie E. Egan
  • Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
    Publication number: 20040266883
    Abstract: This invention provides the methodology and agents for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention of proteins. Thus, the methods and agents of the present invention provide for the release of normally retained proteins from the endoplasmic reticulum. The present invention is particularly useful for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention or degradation of mis-assembled or mis-folded proteins. In certain embodiments of the invention the agents include at least one curcuminoid.
    Type: Application
    Filed: March 11, 2004
    Publication date: December 30, 2004
    Applicant: Yale University
    Inventors: Michael J. Caplan, Marie E. Egan
  • Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
    Patent number: 6753343
    Abstract: This invention provides the methodology and agents for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention of proteins. Thus, the methods and agents of the present invention provide for the release of normally retained proteins from the endoplasmic reticulum. The present invention is particularly useful for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention or degradation of mis-assembled or mis-folded proteins.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: June 22, 2004
    Assignee: Seer Pharmaceuticals, LLC
    Inventors: Michael S. Caplan, Marie E. Egan
  • Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
    Publication number: 20030236300
    Abstract: This invention provides the methodology and agents for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention of proteins. Thus, the methods and agents of the present invention provide for the release of normally retained proteins from the endoplasmic reticulum. The present invention is particularly useful for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention or degradation of mis-assembled or mis-folded proteins.
    Type: Application
    Filed: January 14, 2003
    Publication date: December 25, 2003
    Applicant: Yale University
    Inventors: Michael J. Caplan, Marie E. Egan
  • Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
    Publication number: 20030149113
    Abstract: This invention provides the methodology and agents for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention of proteins. Thus, the methods and agents of the present invention provide for the release of normally retained proteins from the endoplasmic reticulum. The present invention is particularly useful for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention or degradation of mis-assembled or mis-folded proteins.
    Type: Application
    Filed: July 22, 2002
    Publication date: August 7, 2003
    Inventors: Michael J. Caplan, Marie E. Egan
  • Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
    Publication number: 20020132770
    Abstract: This invention provides the methodology and agents for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention of proteins. Thus, the methods and agents of the present invention provide for the release of normally retained proteins from the endoplasmic reticulum. The present invention is particularly useful for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention or degradation of mis-assembled or mis-folded proteins.
    Type: Application
    Filed: October 12, 2001
    Publication date: September 19, 2002
    Inventors: Michael T. Caplan, Marie E. Egan
  • Conductance of improperly folded proteins through the secretory pathway
    Patent number: 6344475
    Abstract: This invention provides the methodology and agents for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention of proteins. Thus, the methods and agents of the present invention provide for the release of normally retained proteins from the endoplasmic reticulum. The present invention is particuarly useful for treating any disease or clinical condition which is at least partly the result of endoplasmic reticulum-associated retention or degradation of mis-assembled or mis-folded proteins.
    Type: Grant
    Filed: October 27, 1999
    Date of Patent: February 5, 2002
    Assignee: Yale University
    Inventors: Michael J. Caplan, Marie E. Egan